SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_002410
Gene Symbol: MGAT5
Description: Homo sapiens mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase (MGAT5), mRNA.
Gene Location: chr2(+):135011829-135206468
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr2:g.134449715C>T COSN6554307 ICGC_MB69 [central_nervous_system][brain][primitive_neuroectodermal_tumour-medulloblastoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3135b accctccCTCCAGCCccgc
 0 GGCUGGAG m8a Disrupted -0.110000 -0.093000 0.010000
hsa-miR-3179 accctCCCTTCagccccgc
 0 AGAAGGGG m6b Created -0.044000 -0.054000 No effect
hsa-miR-3652 accctcccTCCAGCCccgc
 0 CGGCUGGA m7b Disrupted -0.109000 -0.059000 0.130000
hsa-miR-4419a accCTCCCTCcagccccgc
 0 UGAGGGAG m7b (m7b->m6b) -0.312000 -0.289000 0.010000
hsa-miR-4430 accctcccTCCAGCCccgc
 0 AGGCUGGA m7b Disrupted -0.074000 -0.062000 0.300000
hsa-miR-4492 accctccctCCAGCCCCgc
 0 GGGGCUGG m8a (m8a->m7b) -0.169000 -0.106000 No effect
hsa-miR-4498 accctccctCCAGCCCcgc
 0 UGGGCUGG m7b (m7b->m6c) -0.228000 -0.118000 No effect
hsa-miR-4510 accCTCCCTCcagccccgc
 0 UGAGGGAG m7b (m7b->m6b) -0.311000 -0.279000 No effect
hsa-miR-4656 accctccctTCAGCCCcgc
 0 UGGGCUGA m7b (m6c->m7b) 0.000000 0.000000 No effect
hsa-miR-4739 acCCTCCCTTcagccccgc
 0 AAGGGAGG m8a (m7a->m8a) 0.008000 -0.020000 No effect
hsa-miR-5001-5p accctccctCCAGCCCcgc
 0 AGGGCUGG m7b (m7b->m6c) -0.209000 -0.109000 No effect
hsa-miR-762 accctccctCCAGCCCCgc
 0 GGGGCUGG m8a (m8a->m7b) -0.244000 -0.125000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.134449938G>A COSN5781657 HX20T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1913 gggagtgGGGGCAGctcag
 0 UCUGCCCC m7b Disrupted -0.212000 -0.166000 6.650000
hsa-miR-22-3p gggagtgggGGCAGCTcag
 0 AAGCUGCC m7b (m7b->m6c) -0.141000 -0.155000 0.010000
hsa-miR-3156-3p gggAGTGGGAGcagctcag
 0 CUCCCACU m8a Created -0.208000 -0.164000 -2.710000
hsa-miR-324-3p gggagtgGGGGCAGctcag
 0 ACUGCCCC m7b Disrupted -0.213000 -0.176000 0.840000
hsa-miR-4286 gggAGTGGGGgcagctcag
 0 ACCCCACU m7b (m7b->m6b) 0.049000 no TS 1.430000
hsa-miR-4313 gggagtGGGGGCagctcag
 0 AGCCCCCU m6b Disrupted -0.513000 -0.404000 4.760000
hsa-miR-532-3p gggaGTGGGAGcagctcag
 0 CCUCCCAC m7b Created -0.183000 -0.212000 -0.960000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.134450211C>G COSN7339155 8061178 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1270 ccctgacATCTCCAtgctg
 0 CUGGAGAU m7b Disrupted 0.127000 0.068000 0.040000
hsa-miR-1273f ccctgaCATCTCCatgctg
 0 GGAGAUGG m7a Disrupted NA NA 0.350000
hsa-miR-3676-5p ccctgacATCTCCatgctg
 0 AGGAGAUC m6b Disrupted 0.057000 0.044000 4.400000
hsa-miR-620 ccctgacATCTCCATgctg
 0 AUGGAGAU m8a Disrupted 0.152000 0.084000 0.020000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.134450351C>T COSN7339156 8016470 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4632 aacagaGGGCGGCccagtg
 0 UGCCGCCC m7b Disrupted -0.130000 no TS 0.270000
hsa-miR-4726-5p aacagagggTGGCCCagtg
 0 AGGGCCAG m6b Created -0.012000 -0.013000 No effect


Mutation Mutation ID Sample Name Cancer Type
chr2:g.134452966A>G COSN1789220 RK099_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr2:g.134453260T>A COSN6210154 RK190_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3162-3p cctgctGGTAGGGAtctta
 0 UCCCUACC m8a Created no TS -0.160000 No effect
hsa-miR-4733-5p cctgctggTTGGGATctta
 0 AAUCCCAA m7b Disrupted 0.057000 no TS 2.120000
hsa-miR-634 ccTGCTGGTTgggatctta
 0 AACCAGCA m8a (m8a->m7a) -0.099000 -0.124000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.134453826A>C COSN15282645 SM-4B295 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1258 atcaCCTAACTatcggttt
 0 AGUUAGGA m7a Created NA NA -0.760000
hsa-miR-3145-3p atcacctAAATATCggttt
 0 AGAUAUUU m7b Disrupted 0.017000 no TS 1.590000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.134454184C>T COSN4796269 tumor_4119027 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][Burkitt_lymphoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1247-5p tggcggGGACGGGgtggtg
 0 ACCCGUCC m7b Disrupted -0.189000 no TS 0.250000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.134454535C>T COSN8758348 SS6003111 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4436a atgtacTGTCCTGgcatag
 0 GCAGGACA m7b Disrupted -0.107000 0.053000 2.210000
hsa-miR-4645-3p atgTACTGTCctggcatag
 0 AGACAGUA m7b (m7b->m6b) -0.245000 -0.094000 0.090000
hsa-miR-4755-3p atgtactgtCCTGGCatag
 0 AGCCAGGC m6b Disrupted -0.635000 -0.466000 0.080000
hsa-miR-4773 atgtaCTGTTCTGgcatag
 0 CAGAACAG m8a Created no TS -0.140000 -0.070000
hsa-miR-5000-3p atgtacTGTCCTGgcatag
 0 UCAGGACA m7b Disrupted -0.117000 0.043000 0.260000
hsa-miR-5006-5p atgtactgtCCTGGCAtag
 0 UUGCCAGG m7b (m7b->m6c) -0.704000 -0.438000 0.240000
hsa-miR-589-3p atgtacTGTTCTGgcatag
 0 UCAGAACA m7b Created -0.175000 -0.277000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.134454587A>G COSN1789222 RK100_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-148a-5p aaactagggAGAACTTTat
 0 AAAGUUCU m8a (m8a->m7b) -0.091000 0.049000 No effect
hsa-miR-3679-3p aaactaGGGGGAActttat
 0 CUUCCCCC m7b Created no TS -0.340000 -0.050000
hsa-miR-4287 aaactAGGGAGAactttat
 0 UCUCCCUU m7a Disrupted -0.395000 -0.209000 No effect
hsa-miR-4469 aaactAGGGAGaactttat
 0 GCUCCCUC m6b Disrupted -0.680000 -0.496000 No effect
hsa-miR-4685-3p aaactAGGGAGAactttat
 0 UCUCCCUU m7a Disrupted -0.374000 -0.185000 No effect
hsa-miR-629-3p aaactaGGGAGAACtttat
 0 GUUCUCCC m8a Disrupted -0.313000 -0.047000 No effect
hsa-miR-148a-5p aaactagggAGAACTTTat
 0 AAAGUUCU m8a (m8a->m7b) -0.091000 0.049000 No effect
hsa-miR-3679-3p aaactaGGGGGAActttat
 0 CUUCCCCC m7b Created no TS -0.340000 -0.050000
hsa-miR-4287 aaactAGGGAGAactttat
 0 UCUCCCUU m7a Disrupted -0.395000 -0.209000 No effect
hsa-miR-4469 aaactAGGGAGaactttat
 0 GCUCCCUC m6b Disrupted -0.680000 -0.496000 No effect
hsa-miR-4685-3p aaactAGGGAGAactttat
 0 UCUCCCUU m7a Disrupted -0.374000 -0.185000 No effect
hsa-miR-629-3p aaactaGGGAGAACtttat
 0 GUUCUCCC m8a Disrupted -0.313000 -0.047000 No effect
hsa-miR-148a-5p aaactagggAGAACTTTat
 0 AAAGUUCU m8a (m8a->m7b) -0.091 0.049 No effect
hsa-miR-3679-3p aaactaGGGGGAActttat
 0 CUUCCCCC m7b Created no TS -0.34 -0.05
hsa-miR-4287 aaactAGGGAGAactttat
 0 UCUCCCUU m7a Disrupted -0.395 -0.209 No effect
hsa-miR-4469 aaactAGGGAGaactttat
 0 GCUCCCUC m6b Disrupted -0.68 -0.496 No effect
hsa-miR-4685-3p aaactAGGGAGAactttat
 0 UCUCCCUU m7a Disrupted -0.374 -0.185 No effect
hsa-miR-629-3p aaactaGGGAGAACtttat
 0 GUUCUCCC m8a Disrupted -0.313 -0.047 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
134448863 rs148616593 - C hsa-miR-1909-3p
hsa-miR-4446-3p
hsa-miR-4656
hsa-miR-4663
hsa-miR-6132
hsa-miR-6722-3p
hsa-miR-6836-5p
12
3
3
3
10
12
10
 gctcagCCCTGCA
gctCAGCCCTgca
gcTCAGCCCtgca
GCTCAGCcctgca
gctcaGCCCTGCA
gctcagCCCTGCA
gctcaGCCCTGCA
 Unknown
Unknown
Unknown
Unknown
Unknown
Unknown
Unknown
N
N
N
N
N
N
N
 -0.139
No Change
No Change
No Change
-0.44
-0.139
-0.471
- hsa-miR-3929
hsa-miR-4419b
hsa-miR-4478
hsa-miR-6511b-5p
hsa-miR-6811-5p
3
3
3
10
10
 gcTCAGCCTgca
gcTCAGCCTgca
gcTCAGCCTgca
gctcaGCCTGCA
gctcaGCCTGCA
 Unknown
Unknown
Unknown
Unknown
Unknown
N
N
N
N
N
 No Change
No Change
No Change
-0.209
-0.219
134448896 rs202011729 C C hsa-miR-1227-5p
hsa-miR-128-1-5p
hsa-miR-128-2-5p
hsa-miR-4492
hsa-miR-4498
hsa-miR-4505
hsa-miR-4731-5p
hsa-miR-5001-5p
hsa-miR-5787
hsa-miR-6762-5p
hsa-miR-6845-5p
hsa-miR-762
4
4
4
9
9
4
4
9
4
3
3
9
 gtGGCCCCAgccc
gtGGCCCCAgccc
gtGGCCCCAgccc
gtggccCCAGCCC
gtggccCCAGCCC
gtggcCCCAGCCc
gtggCCCCAGCcc
gtggccCCAGCCC
gtggcCCCAGCCc
gTGGCCCCAgccc
gTGGCCCCAgccc
gtggccCCAGCCC
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
N
N
N
N
N
N
 -0.219
-0.211
-0.204
-0.123
-0.132
-0.125
-0.134
-0.123
-0.107
-0.415
-0.394
-0.132
G hsa-miR-1199-3p
hsa-miR-604
hsa-miR-6829-5p
4
4
9
 gtGGCCGCAgccc
gtggcCGCAGCCc
gtggccGCAGCCC
 Created
Created
Created
N
N
N
 -0.25
-0.143
-0.111

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