SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_013283
Gene Symbol: MAT2B
Description: Homo sapiens methionine adenosyltransferase II, beta (MAT2B), transcript variant 1, mRNA.
Gene Location: chr5(+):162932584-162946328
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr5:g.163518456T>G COSN9416369 AOCS-088-3-8 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-548a-5p tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.036000 no TS 0.150000
hsa-miR-548ab tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.036000 no TS 0.010000
hsa-miR-548ak tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.036000 no TS 0.080000
hsa-miR-548am-5p tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.033000 no TS 0.060000
hsa-miR-548ap-5p tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.036000 no TS 0.080000
hsa-miR-548aq-5p tatgagTACTTTaattgtg
 2
 GAAAGUAA m6b Disrupted -0.033000 no TS 0.470000
hsa-miR-548ar-5p tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.040000 no TS 0.090000
hsa-miR-548as-5p tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.033000 no TS 0.010000
hsa-miR-548au-5p tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.033000 no TS 0.020000
hsa-miR-548av-5p tatgaGTACTTTaattgtg
 2
 AAAAGUAC m7b Disrupted -0.256000 no TS 2.410000
hsa-miR-548b-5p tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.033000 no TS 0.020000
hsa-miR-548c-5p tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.033000 no TS 0.060000
hsa-miR-548d-5p tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.033000 no TS No effect
hsa-miR-548h-5p tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.036000 no TS 0.010000
hsa-miR-548i tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.036000 no TS 0.200000
hsa-miR-548j tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.036000 no TS 0.260000
hsa-miR-548k tatgaGTACTTTaattgtg
 2
 AAAAGUAC m7b Disrupted -0.256000 no TS 1.280000
hsa-miR-548l tatgagTACTTTaattgtg
 2
 AAAAGUAU m6b Disrupted -0.035000 no TS 0.060000
hsa-miR-548o-5p tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.033000 no TS 0.060000
hsa-miR-548w tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.036000 no TS 0.030000
hsa-miR-548y tatgagTACTTTaattgtg
 2
 AAAAGUAA m6b Disrupted -0.040000 no TS 1.330000
hsa-miR-559 tatgagTACTTTAattgtg
 2
 UAAAGUAA m7a Disrupted -0.043000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr5:g.163519019T>C COSN6872003 RK191_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4307 taatatAAACATataactg
 0 AAUGUUUU m6b Created no TS -0.014000 -0.050000
hsa-miR-5011-5p taatataaATATATAactg
 7
 UAUAUAUA m7a Disrupted 0.038000 no TS -0.500000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.163519100A>G COSN6872004 RK216_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4432 gggccttgtGAGTCTTTtc
 0 AAAGACUC m8a (m7b->m8a) no TS -0.213000 1.590000
hsa-miR-4457 gggCCTTGTGAgtcttttc
 0 UCACAAGG m8a Created no TS -0.278000 -6.560000
hsa-miR-513b gggcCTTGTGAgtcttttc
 0 UUCACAAG m7b Created no TS -0.096000 -0.850000
hsa-miR-624-3p gggCCTTGTGagtcttttc
 11
 CACAAGGU m7a (m6a->m7a) -0.136000 no TS 3.550000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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