| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_145333 |
|---|---|
| Gene Symbol: | MAP3K7 |
| Description: | Homo sapiens mitogen-activated protein kinase kinase kinase 7 (MAP3K7), transcript variant A, mRNA. |
| Gene Location: | chr6(-):91225352-91296907 |
| Browse Associations | |
| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr6:g.90516224A>C | COSN6514777 | HX37T | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-4468 |
tgtatatgcCTGCTCattg |
0 | AGAGCAGA | m6b | Created | no TS | -0.115000 | No effect |
| hsa-miR-448 |
tgtATATGCAtgctcattg |
8 |
UUGCAUAU | m7b | (m7b->m6c) | -0.411000 | -0.346000 |
0.010000 |
| hsa-miR-4690-5p |
tgtatatGCCTGCTCattg |
0 | GAGCAGGC | m8a | Created | no TS | -0.232000 | No effect |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr6:g.90516388C>T | COSN7797000 | PCSI_0164_Pa_P_526 | [pancreas][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-1256 |
ttctgAATGCCaactgcct |
16 |
AGGCAUUG | m6b | Disrupted | -0.121000 | no TS | No effect |
| hsa-miR-181a-5p |
ttcTGAATGTcaactgcct |
0 | AACAUUCA | m7b | (m6c->m7b) | no TS | -0.056000 |
0.920000 |
| hsa-miR-181b-5p |
ttcTGAATGTcaactgcct |
0 | AACAUUCA | m7b | (m6c->m7b) | no TS | -0.056000 |
2.040000 |
| hsa-miR-181c-5p |
ttcTGAATGTcaactgcct |
0 | AACAUUCA | m7b | (m6c->m7b) | no TS | -0.065000 |
1.120000 |
| hsa-miR-181d |
ttcTGAATGTcaactgcct |
0 | AACAUUCA | m7b | (m6c->m7b) | no TS | -0.056000 |
2.100000 |
| hsa-miR-4262 |
ttcTGAATGTCaactgcct |
0 | GACAUUCA | m8a | Created | no TS | -0.065000 |
-0.600000 |
| hsa-miR-4642 |
ttctgaATGCCAactgcct |
11 |
AUGGCAUC | m6b | Disrupted | -0.307000 | -0.206000 | No effect |
| hsa-miR-4715-5p |
ttctgaatGCCAACTgcct |
7 |
AAGUUGGC | m7b | Disrupted | -0.233000 | no TS |
0.180000 |
| hsa-miR-489 |
ttctgaATGTCAactgcct |
0 | GUGACAUC | m6b | Created | no TS | -0.064000 |
-2.930000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr6:g.90516410G>C | COSN8314879 | TCGA-GI-A2C9-01 | [breast][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-548ag |
tgagtgTTACCTTTttggc |
0 | AAAGGUAA | m8a | Created | no TS | -0.079000 |
-9.940000 |
| hsa-miR-548ai |
tgagtgTTACCTTTttggc |
0 | AAAGGUAA | m8a | Created | no TS | -0.088000 |
-15.290000 |
| hsa-miR-548m |
tgagtgtTACCTTTttggc |
3 |
CAAAGGUA | m7b | Created | -0.011000 | -0.114000 |
-0.110000 |
| hsa-miR-570-5p |
tgagtgTTACCTTTttggc |
0 | AAAGGUAA | m8a | Created | no TS | -0.088000 |
-15.290000 |