SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001252008
Gene Symbol: LUZP2
Description: Homo sapiens leucine zipper protein 2 (LUZP2), transcript variant 1, mRNA.
Browse Associations

Somatic mutations that impact miRNA target sites




Mutation Mutation ID Sample Name Cancer Type
chr11:g.25078789G>T COSN8641428 2275_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr11:g.25078844T>C COSN8440171 AOCS-134-3-9 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1294 ataACCTCACtgaattgaa
0 UGUGAGGU m7b (m6b->m7b) no TS -0.301000 -0.420000
hsa-miR-4276 ataaccTCACTGAattgaa
0 CUCAGUGA m7b Created no TS -0.311000 -0.560000
hsa-miR-5190 ataaccTCACTGaattgaa
0 CCAGUGAC m6b Created no TS -0.128000 -0.030000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25079273C>G COSN5904939 RK210_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-136-5p tcatATGGAGaaaatattt
0 ACUCCAUU m6b Created 0.072000 -0.030000 -0.060000
hsa-miR-2355-3p tcatatGGACAAaatattt
0 AUUGUCCU m6b Disrupted -0.115000 no TS No effect
hsa-miR-4646-3p tcatatGGACAAaatattt
0 AUUGUCCC m6b Disrupted -0.119000 no TS No effect
hsa-miR-515-5p tcataTGGAGAAaatattt
0 UUCUCCAA m7a Created -0.084000 -0.190000 No effect
hsa-miR-519e-5p tcataTGGAGAAaatattt
0 UUCUCCAA m7a Created -0.073000 -0.179000 No effect
hsa-miR-629-3p tcatatGGAGAAaatattt
0 GUUCUCCC m6b Created no TS -0.089000 -1.460000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25079644G>A COSN4721003 tumor_4177434 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-223-5p caaaaaAATACACtcatga
0 CGUGUAUU m7b Created no TS -0.070000 -0.160000
hsa-miR-4280 caaaaaaaTACACTCatga
0 GAGUGUAG m7a Created NA NA -0.290000
hsa-miR-4658 caaaaaaatACACTCAtga
0 GUGAGUGU m7b (m6c->m7b) no TS -0.158000 -1.080000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25079914G>A COSN15368122 0084_CRUK_PC_0084_T1_DNA [prostate][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1277-5p aataaaaATATATTaaagg
0 AAAUAUAU m7b Created 0.055000 0.182000 No effect
hsa-miR-374c-5p aataaaaaTGTATTAaagg
0 AUAAUACA m7b Disrupted -0.120000 -0.145000 0.160000
hsa-miR-655 aataaaaaTGTATTAaagg
0 AUAAUACA m7b Disrupted -0.151000 -0.145000 2.220000
hsa-miR-889 aataaaaatATATTAAagg
0 UUAAUAUC m7a (m6b->m7a) 0.269000 0.375000 -0.050000


Mutation Mutation ID Sample Name Cancer Type
chr11:g.25080031G>A COSN6999506 8047881 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr11:g.25080297G>T COSN1526033 RK022_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-139-5p ccaACTGTAGgatgaggta
0 UCUACAGU m7b (m7b->m6b) 0.010000 no TS 0.090000
hsa-miR-154-3p ccaactGTATGATgaggta
0 AAUCAUAC m7b Created -0.067000 -0.037000 -0.010000
hsa-miR-155-3p ccaacTGTAGGAtgaggta
0 CUCCUACA m7b Disrupted 0.003000 no TS 0.110000
hsa-miR-4793-5p ccaactgtAGGATGaggta
0 ACAUCCUG m6b Disrupted 0.008000 -0.039000 2.940000
hsa-miR-485-3p ccaacTGTATGAtgaggta
0 GUCAUACA m7b Created -0.035000 0.060000 No effect
hsa-miR-487a ccaactGTATGATgaggta
0 AAUCAUAC m7b Created -0.067000 -0.009000 No effect
hsa-miR-539-3p ccaacTGTATGATgaggta
0 AUCAUACA m8a Created -0.035000 0.023000 -0.050000
hsa-miR-139-5p ccaACTGTAGgatgaggta
0 UCUACAGU m7b (m7b->m6b) 0.01 no TS 0.09
hsa-miR-154-3p ccaactGTATGATgaggta
0 AAUCAUAC m7b Created -0.067 -0.037 -0.01
hsa-miR-155-3p ccaacTGTAGGAtgaggta
0 CUCCUACA m7b Disrupted 0.003 no TS 0.11
hsa-miR-4793-5p ccaactgtAGGATGaggta
0 ACAUCCUG m6b Disrupted 0.008 -0.039 2.94
hsa-miR-485-3p ccaacTGTATGAtgaggta
0 GUCAUACA m7b Created -0.035 0.06 No effect
hsa-miR-487a ccaactGTATGATgaggta
0 AAUCAUAC m7b Created -0.067 -0.009 No effect
hsa-miR-539-3p ccaacTGTATGATgaggta
0 AUCAUACA m8a Created -0.035 0.023 -0.05

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25080332T>G COSN8534753 tumor_4163639 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][diffuse_large_B_cell_lymphoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-302a-5p ttaagcagGTTTAAGTtag
0 ACUUAAAC m8a Disrupted 0.322000 0.189000 0.590000
hsa-miR-649 ttaagCAGGTTTaagttag
0 AAACCUGU m7a Disrupted NA NA No effect
hsa-miR-652-5p ttaagcAGGGTTaagttag
0 CAACCCUA m6b Created -0.058000 -0.068000 -1.170000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25080371T>C COSN1526034 RK023_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-205-3p ttaggtatCTGAAATgcat
0 GAUUUCAG m7b Disrupted 0.146000 0.043000 No effect
hsa-miR-3942-3p ttaggtATCTGAAAtgcat
0 UUUCAGAU m8a Disrupted -0.105000 -0.217000 No effect
hsa-miR-5100 ttaggtATCTGAAatgcat
0 UUCAGAUC m7a Disrupted -0.030000 -0.086000 No effect
hsa-miR-205-3p ttaggtatCTGAAATgcat
0 GAUUUCAG m7b Disrupted 0.146 0.043 No effect
hsa-miR-3942-3p ttaggtATCTGAAAtgcat
0 UUUCAGAU m8a Disrupted -0.105 -0.217 No effect
hsa-miR-5100 ttaggtATCTGAAatgcat
0 UUCAGAUC m7a Disrupted -0.03 -0.086 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25080479C>T COSN8440172 AOCS-146-1-9 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1225-5p ccggcTACCCAaggaaaaa
0 GUGGGUAC m6b Disrupted -0.009000 no TS 0.050000
hsa-miR-196a-5p ccggCTACCTAaggaaaaa
0 UAGGUAGU m7a Created no TS -0.016000 -1.600000
hsa-miR-196b-5p ccggCTACCTAaggaaaaa
0 UAGGUAGU m7a Created no TS -0.016000 -0.980000
hsa-miR-197-5p ccggCTACCCaaggaaaaa
0 CGGGUAGA m6b Disrupted -0.040000 no TS 0.200000
hsa-miR-212-5p ccggctacCCAAGGaaaaa
0 ACCUUGGC m6b Disrupted -0.025000 no TS 2.890000
hsa-miR-3132 ccggCTACCCAaggaaaaa
0 UGGGUAGA m7a Disrupted -0.040000 no TS 0.530000
hsa-miR-3189-3p ccggctaCCCAAGGaaaaa
0 CCCUUGGG m7b Disrupted -0.137000 no TS 2.890000
hsa-miR-331-5p ccggcTACCTAaggaaaaa
0 CUAGGUAU m6b Created no TS 0.040000 -0.200000
hsa-miR-3927 ccggCTACCTaaggaaaaa
0 CAGGUAGA m6b Created no TS 0.000000 -0.280000
hsa-miR-502-5p ccggctaccCAAGGAaaaa
0 AUCCUUGC m6b Disrupted 0.008000 no TS 3.650000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25080927C>A COSN6999507 8066440 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-126-5p gatatTAATAATGttttta
0 CAUUAUUA m8a Created no TS 0.126000 No effect
hsa-miR-4477a gataTTAATAatgttttta
0 CUAUUAAG m6b Created 0.368000 0.525000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25081179A>T COSN8440173 AOCS-106-1-1 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3914 attacaGGTTCCTgccacc
0 AAGGAACC m7b Created -0.153000 -0.161000 No effect
hsa-miR-4722-5p attacaggtTCCTGCCacc
0 GGCAGGAG m7a (m6b->m7a) NA NA -0.490000
hsa-miR-4736 attacaggtACCTGCCacc
0 AGGCAGGU m7b (m7b->m6c) -0.046000 0.005000 1.190000
hsa-miR-649 attACAGGTTcctgccacc
0 AAACCUGU m7b (m6b->m7b) no TS 0.044000 No effect
hsa-miR-657 attacaggtACCTGCCacc
0 GGCAGGUU m7a (m7a->m6b) NA NA No effect
hsa-miR-873-5p attacagGTTCCTGCcacc
0 GCAGGAAC m8a Created 0.047000 0.143000 -0.050000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25081218G>A COSN6999508 8067180 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-340-3p tttttaataGAGACGGggt
0 UCCGUCUC m7b (m7b->m6c) -0.124000 no TS 0.770000
hsa-miR-4477a tttTTAATAGagacggggt
0 CUAUUAAG m7a (m7a->m6a) 0.368000 0.543000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25081295C>T COSN6999509 8035543 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-149-3p agtctCCTCCCaaaatgct
0 AGGGAGGG m6b Disrupted 0.011000 0.021000 2.760000
hsa-miR-30b-3p agtctCCTCCCAaaatgct
0 CUGGGAGG m7b Disrupted 0.012000 0.092000 No effect
hsa-miR-30c-1-3p agtctcCTCCCAaaatgct
0 CUGGGAGA m6b Disrupted 0.146000 0.143000 0.010000
hsa-miR-30c-2-3p agtctcCTCCCAaaatgct
0 CUGGGAGA m6b Disrupted 0.139000 0.139000 No effect
hsa-miR-3122 agtctccTCCCAAaatgct
0 GUUGGGAC m6b Disrupted 0.113000 0.074000 0.010000
hsa-miR-3689a-3p agtctCCTCCCAaaatgct
0 CUGGGAGG m7b Disrupted 0.005000 0.085000 0.030000
hsa-miR-3689b-3p agtctCCTCCCAaaatgct
0 CUGGGAGG m7b Disrupted 0.002000 0.082000 0.010000
hsa-miR-3689c agtctCCTCCCAaaatgct
0 CUGGGAGG m7b Disrupted 0.002000 0.082000 0.010000
hsa-miR-3913-5p agtctccTCCCAAAatgct
0 UUUGGGAC m7a Disrupted 0.095000 0.056000 0.010000
hsa-miR-4728-5p agtctCCTCCCAaaatgct
0 UGGGAGGG m7a Disrupted -0.023000 0.004000 1.630000
hsa-miR-765 agtCTCCTCCcaaaatgct
0 UGGAGGAG m7b (m7b->m6b) -0.057000 no TS 1.590000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25081300A>G ICGC_83DAD004-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-338-3p cctcccaaaATGCTGGgat
0 UCCAGCAU m7b (m7b->m6c) -0.02 no TS 0.09
hsa-miR-4310 cctcccaaAATGCTGggat
0 GCAGCAUU m7b Disrupted -0.148 -0.232 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25081637T>G COSN8218203 ASHPC_0006_Pa_P [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3908 ggggcCATTGCTCacatat
0 GAGCAAUG m8a Created -0.068000 -0.038000 -0.010000
hsa-miR-539-5p ggggccATTTCTCacatat
0 GGAGAAAU m7b Disrupted -0.036000 -0.118000 0.020000
hsa-miR-5680 ggggcCATTTCTCacatat
0 GAGAAAUG m8a Disrupted 0.380000 0.281000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25081890C>A COSN14854032 LP6005334-DNA_C03 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-182-3p caaccAGAACCAacaattg
0 UGGUUCUA m7a Disrupted -0.177000 -0.091000 0.010000
hsa-miR-218-1-3p caaccaGAACCAacaattg
0 AUGGUUCC m6b Disrupted -0.070000 no TS 1.460000
hsa-miR-659-3p caaccaGAACCAAcaattg
0 CUUGGUUC m7b Disrupted -0.096000 no TS 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25082097C>T COSN5825530 SS6003323 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-183-3p tgaaTAATTCAgtcattca
0 GUGAAUUA m7b Disrupted -0.073000 -0.069000 No effect
hsa-miR-3136-5p tgaataatTCAGTCAttca
0 CUGACUGA m7b Disrupted -0.199000 no TS No effect
hsa-miR-4439 tgaataatTCAGTCAttca
0 GUGACUGA m7b Disrupted -0.208000 no TS 0.010000
hsa-miR-4513 tgaataatTCAGTCattca
0 AGACUGAC m6b Disrupted -0.114000 no TS 0.040000
hsa-miR-4680-3p tgaatAATTCAGtcattca
0 UCUGAAUU m7b Disrupted -0.082000 no TS 0.030000
hsa-miR-944 tgAATAATTTagtcattca
0 AAAUUAUU m8a (m7a->m8a) 0.725000 0.697000 -0.090000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25082164C>A COSN8641429 J88_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-101-5p actaggttGATAACTtttt
0 CAGUUAUC m7b Created -0.087000 -0.249000 -0.100000
hsa-miR-4766-3p actaggTTGCTAacttttt
0 AUAGCAAU m6b Disrupted -0.224000 -0.140000 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25082264T>C COSN5904940 RK176_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-410 taagacaGTTATATgtaaa
0 AAUAUAAC m7b Disrupted -0.260000 -0.197000 No effect
hsa-miR-5580-3p taagacagtCATATGTaaa
0 CACAUAUG m7b (m6c->m7b) -0.022000 -0.190000 No effect
hsa-miR-943 taagACAGTCAtatgtaaa
0 CUGACUGU m7b Created -0.176000 -0.373000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25082326T>C COSN8440174 AOCS-107-1-4 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4719 aaacgatATTTGTGAactt
0 UCACAAAU m8a Disrupted -0.154000 0.033000 0.350000


Mutation Mutation ID Sample Name Cancer Type
chr11:g.25082351T>G COSN8942096 SS6003320 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr11:g.25082540T>A COSN8218204 PCSI_0279_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4680-5p caaactatGAGTTCatttg
0 AGAACUCU m6b Created -0.120000 -0.272000 -0.050000
hsa-miR-4789-3p caaacTATGTGTtcatttg
0 CACACAUA m7b Disrupted -0.122000 no TS 0.070000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25082546T>C COSN1130970 HX13T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3646 atgtgTTCATTTggattgt
0 AAAAUGAA m7b Disrupted 0.342000 0.344000 No effect
hsa-miR-3691-3p atgtgttcACTTGGattgt
0 ACCAAGUC m6b Created no TS -0.157000 -0.350000
hsa-miR-3646 atgtgTTCATTTggattgt
0 AAAAUGAA m7b Disrupted 0.342 0.344 No effect
hsa-miR-3691-3p atgtgttcACTTGGattgt
0 ACCAAGUC m6b Created no TS -0.157 -0.35

Mutation Mutation ID Sample Name Cancer Type
chr11:g.25082551A>G COSN4721004 tumor_4158726 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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