SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_206943
Gene Symbol: LTBP1
Description: Homo sapiens latent transforming growth factor beta binding protein 1 (LTBP1), transcript variant 2, mRNA.
Gene Location: chr2(+):33172368-33624575
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Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr2:g.33398772A>T COSN1237900 HCC56T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3646 tctgTTCATTTgtaaaatt
 8
 AAAAUGAA m7b Created -0.065000 -0.078000 -0.010000
hsa-miR-520d-5p tctgttcaTTTGTAaaatt
 1
 CUACAAAG m6b Created -0.080000 -0.075000 -0.010000
hsa-miR-524-5p tctgttcaTTTGTAaaatt
 1
 CUACAAAG m6b Created -0.098000 -0.099000 -0.010000
hsa-miR-5580-3p tctgttCATATGTaaaatt
 16
 CACAUAUG m7b Disrupted -0.287000 -0.037000 0.850000
hsa-miR-3646 tctgTTCATTTgtaaaatt
 0 AAAAUGAA m7b Created -0.065 -0.078 -0.01
hsa-miR-520d-5p tctgttcaTTTGTAaaatt
 0 CUACAAAG m6b Created -0.08 -0.075 -0.01
hsa-miR-524-5p tctgttcaTTTGTAaaatt
 0 CUACAAAG m6b Created -0.098 -0.099 -0.01
hsa-miR-5580-3p tctgttCATATGTaaaatt
 16
 CACAUAUG m7b Disrupted -0.287 -0.037 0.85

Mutation Mutation ID Sample Name Cancer Type
chr2:g.33398896T>G COSN1836400 RK014_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3124-3p tggtGGAAAGattttatat
 0 ACUUUCCU m6b Created no TS -0.083000 -0.010000
hsa-miR-4668-3p tggtggaaaGATTTTatat
 0 GAAAAUCC m6b Created 0.049000 0.050000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.33399051C>T COSN1836401 RK012_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4645-5p aattcccgGCCTGGagcat
 0 ACCAGGCA m6b Disrupted -0.137000 no TS 0.970000
hsa-miR-4645-5p aattcccgGCCTGGagcat
 0 ACCAGGCA m6b Disrupted -0.137 no TS 0.97

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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