SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_152447
Gene Symbol: LRFN5
Description: Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), mRNA.
Gene Location: chr14(+):42076763-42373752
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr14:g.41904332C>T COSN7231000 8050939 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-718 tgatgacGGCGGAActggc
 4
 CUUCCGCC m7b Disrupted -0.228000 no TS 1.870000


Mutation Mutation ID Sample Name Cancer Type
chr14:g.41904405T>- ICGC_ssm_v3_107215 HCC4T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr14:g.41904424A>G COSN6249475 RK122_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4659a-3p aaaaaAGAAGAAAagccta
 11
 UUUCUUCU m8a Created -0.210000 -0.448000 -0.030000
hsa-miR-4659b-3p aaaaaAGAAGAAAagccta
 11
 UUUCUUCU m8a Created -0.210000 -0.427000 -0.060000
hsa-miR-4778-3p aaaaAAGAAGAaaagccta
 0 UCUUCUUC m7a Created no TS -0.081000 -0.005800

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
41904287 rs187190762 G G hsa-miR-4659a-3p
hsa-miR-4659b-3p
hsa-miR-6875-3p
11
11
13
 gtcgtAGAAGAAA
gtcgtAGAAGAAA
gtcgtaGAAGAAA
 Disrupted
Disrupted
Disrupted
N
N
N
 -0.21
-0.21
-0.026

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