| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_057159 |
|---|---|
| Gene Symbol: | LPAR1 |
| Description: | Homo sapiens lysophosphatidic acid receptor 1 (LPAR1), transcript variant 1, mRNA. |
| Gene Location: | chr9(-):113636053-113800365 |
| Browse Associations | |
| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.110873846C>A | COSN5695376 | RK145_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3665 |
tggtagccaCACCTGCaat |
3 |
AGCAGGUG | m7b | (m7b->m6b) | -0.461000 | -0.177000 |
2.020000 |
|
| hsa-miR-3934 |
tggtagccACACCTGcaat |
2 |
UCAGGUGU | m7b | Disrupted | -0.160000 | no TS |
6.020000 |
|
| hsa-miR-4464 |
tggtagcCAAACCTgcaat |
0 | AAGGUUUG | m7b | Created | no TS | -0.100000 |
-0.210000 |
|
| hsa-miR-4474-3p |
tggtAGCCACAcctgcaat |
0 | UUGUGGCU | m7b | Disrupted | -0.214000 | no TS |
0.170000 |
|
| hsa-miR-4748 |
tggtagcCAAACCTgcaat |
0 | GAGGUUUG | m7b | Created | no TS | -0.100000 |
-0.130000 |
|
| hsa-miR-644a |
tggtaGCCACACctgcaat |
0 | AGUGUGGC | m7b | Disrupted | -0.291000 | no TS |
5.770000 |
|
| hsa-miR-657 |
tggtagccaAACCTGCaat |
3 |
GGCAGGUU | m7b | (m6b->m7b) | -0.194000 | -0.429000 | No effect | |
| hsa-miR-764 |
tggtagccaCACCTGCaat |
0 | GCAGGUGC | m7a | (m7a->m6a) | NA | NA |
0.110000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.110874099G>A | COSN14789656 | CHC205T | [liver][NS][carcinoma][hepatocellular_carcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3145-3p |
atgtgAAATATCatcttgt |
5 |
AGAUAUUU | m7b | Created | 0.034000 | -0.087000 | No effect | |
| hsa-miR-3682-3p |
atgtgaaaTATCATCttgt |
0 | UGAUGAUA | m7b | Created | no TS | -0.172000 |
0.060000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr9:g.110875327G>A | COSN8118057 | 8012341 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1236 |
tgtgagaGAAGAGaaaagt |
0 | CCUCUUCC | m6b | Created | no TS | -0.077000 |
-5.480000 |
|
| hsa-miR-3183 |
tgtgAGAGAGGagaaaagt |
4 |
GCCUCUCU | m7b | Disrupted | -0.292000 | no TS |
1.100000 |
|
| hsa-miR-4279 |
tgtgagaGAGGAGAaaagt |
0 | CUCUCCUC | m7b | Disrupted | -0.355000 | no TS |
-4.590000 |
|
| hsa-miR-4723-3p |
tgtgAGAGAGGagaaaagt |
4 |
CCCUCUCU | m7b | Disrupted | -0.324000 | no TS |
3.150000 |
|
| hsa-miR-4753-3p |
tgtgagagAAGAGAAaagt |
0 | UUCUCUUU | m7a | Created | no TS | -0.057000 |
-0.410000 |
|
| hsa-miR-4768-5p |
tgtGAGAGAAgagaaaagt |
0 | AUUCUCUC | m7b | (m6c->m7b) | no TS | -0.185000 |
-0.030000 |
|
| hsa-miR-629-3p |
tgtgagagaGGAGAAaagt |
2 |
GUUCUCCC | m6b | Disrupted | -0.087000 | no TS | No effect | |
| hsa-miR-942 |
tgtgAGAGAAGAgaaaagt |
0 | UCUUCUCU | m8a | Created | no TS | -0.222000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr9:g.110875403G>C | COSN9275531 | C0074T | [kidney][NS][other][neoplasm] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-218-1-3p |
ctgagatgaGGAACCAgcc |
2 |
AUGGUUCC | m7b | (m7b->m6b) | -0.187000 | no TS |
0.810000 |
| hsa-miR-4326 |
ctgagatGAGGAACcagcc |
2 |
UGUUCCUC | m7b | Disrupted | -0.218000 | no TS |
6.010000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 110873852 | rs148202320 | - | TGGT | 0 |
|
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| - |
hsa-miR-4474-3p hsa-miR-6069 hsa-miR-644a |
6 6 7 |
agctctAGCCACAcc agctCTAGCCAcacc agctctaGCCACACc |
Unknown Unknown Unknown |
N N N |
0.006 -0.172 0.006 |
|||
| 110874099 | rs15991 | G | |||||||
| A |
hsa-miR-205-3p hsa-miR-3145-3p hsa-miR-3682-3p |
15 4 3 |
TGAAATAtcatct tgAAATATCAtct tgaaaTATCATCt |
Created Created Created |
N N N |
-0.014 -0.121 -0.172 |
|||
| 110875400 | rs181526130 | A | A |
hsa-miR-218-1-3p hsa-miR-4326 hsa-miR-670-3p |
2 2 2 |
tgaGGAACCAgcc tGAGGAACcagcc TGAGGAAccagcc |
Disrupted Disrupted Disrupted |
N N N |
-0.187 -0.218 -0.128 |
| G |
hsa-miR-149-5p hsa-miR-4268 hsa-miR-5580-5p |
2 2 2 |
tgagGAGCCAGcc tGAGGAGCcagcc tgaggAGCCAGCc |
Created Created Created |
N N N |
-0.178 -0.287 -0.209 |