SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_153371 |
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Gene Symbol: | LNX2 |
Description: | Homo sapiens ligand of numb-protein X 2 (LNX2), mRNA. |
Gene Location: | chr13(-):28120049-28194720 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr13:g.27545927T>C | COSN15225193 | LP6005334-DNA_E03 | [oesophagus][NS][carcinoma][adenocarcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-135a-5p |
aaataaAAGCCATcctttc |
0 | UAUGGCUU | m7b | Created | no TS | -0.272000 |
-0.080000 |
|
hsa-miR-135b-5p |
aaataaAAGCCATcctttc |
0 | UAUGGCUU | m7b | Created | no TS | -0.272000 |
-0.070000 |
|
hsa-miR-2392 |
aaataaaagCCATCCTttc |
0 | UAGGAUGG | m7b | (m6b->m7b) | no TS | -0.215000 | No effect | |
hsa-miR-3119 |
aaatAAAAGCCAtcctttc |
0 | UGGCUUUU | m8a | Created | -0.050000 | -0.412000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr13:g.27545962A>G | COSN7397364 | 8067246 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-302a-5p |
gatGTTTAAGTaatggtgt |
0 | ACUUAAAC | m8a | Created | no TS | -0.157000 |
-1.510000 |
|
hsa-miR-885-5p |
gatgtttaaGTAATGGtgt |
0 | UCCAUUAC | m7b | (m6b->m7b) | no TS | -0.255000 |
-0.010000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr13:g.27547490T>C | COSN1605046 | RK115_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-30b-3p |
tgtaatCTCCCAatattca |
2 |
CUGGGAGG | m6b | Created | -0.159000 | -0.258000 |
-0.020000 |
|
hsa-miR-30c-1-3p |
tgtaaTCTCCCAatattca |
1 |
CUGGGAGA | m7b | Created | -0.103000 | -0.379000 |
-0.010000 |
|
hsa-miR-30c-2-3p |
tgtaaTCTCCCAatattca |
1 |
CUGGGAGA | m7b | Created | -0.109000 | -0.385000 | No effect | |
hsa-miR-3689a-3p |
tgtaatCTCCCAatattca |
2 |
CUGGGAGG | m6b | Created | -0.169000 | -0.268000 | No effect | |
hsa-miR-3689b-3p |
tgtaatCTCCCAatattca |
2 |
CUGGGAGG | m6b | Created | -0.169000 | -0.268000 | No effect | |
hsa-miR-3689c |
tgtaatCTCCCAatattca |
2 |
CUGGGAGG | m6b | Created | -0.169000 | -0.268000 | No effect | |
hsa-miR-4461 |
tgtaatcTCTCAATattca |
3 |
GAUUGAGA | m7b | Disrupted | -0.141000 | no TS |
0.190000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr13:g.27547655C>G | COSN6225429 | RK187_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-369-5p |
caggatggtGTCGATCTcc |
0 | AGAUCGAC | m8a | (m7a->m8a) | no TS | -0.183000 |
1.580000 |
|
hsa-miR-4786-5p |
caggaTGGTCTCgatctcc |
2 |
UGAGACCA | m7b | Disrupted | -0.119000 | no TS |
3.550000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr13:g.27547729C>T | ICGC_87A2B5E4-2A78-11E2-96E7-04FD496BB9B8 | CPCG_0102_Pr_P_P1 | ProstateCancer(OICR,CA) | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1228-3p |
gactacAGGTGTGtgccac |
0 | UCACACCU | m7b | Created | -0.326 | -0.399 |
-0.01 |
|
hsa-miR-329 |
gactacaGGTGTGTgccac |
0 | AACACACC | m7b | Created | no TS | -0.078 |
-0.28 |
|
hsa-miR-362-3p |
gactacaGGTGTGTgccac |
0 | AACACACC | m7b | Created | no TS | -0.069 |
-0.01 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr13:g.27547749C>T | ICGC_87A2BB70-2A78-11E2-96E7-04FD496BB9B8 | CPCG_0102_Pr_P_P1 | ProstateCancer(OICR,CA) | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3664-3p |
tcagccTCCTGAGtagctg |
0 | UCUCAGGA | m7b | Created | no TS | -0.034 |
-1.58 |
|
hsa-miR-4433-3p |
tcagcCTCCTGagtagctg |
0 | ACAGGAGU | m6b | Created | -0.023 | -0.082 |
-11.12 |
|
hsa-miR-4459 |
tcagCCTCCTGagtagctg |
0 | CCAGGAGG | m7b | Created | -0.076 | -0.297 |
-2.03 |
|
hsa-miR-4695-5p |
tcaGCCTCCTGagtagctg |
0 | CAGGAGGC | m8a | Created | -0.066 | -0.215 |
-2.3 |
|
hsa-miR-4768-3p |
tcagcCTCCTGagtagctg |
0 | CCAGGAGA | m6b | Created | -0.169 | -0.201 |
-2.93 |
|
hsa-miR-510 |
tcagcctCCTGAGTAgctg |
0 | UACUCAGG | m8a | Created | no TS | -0.178 |
-1.52 |
|
hsa-miR-512-5p |
tcagcctcCTGAGTagctg |
0 | CACUCAGC | m6b | Created | no TS | -0.033 |
-6.72 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr13:g.27547788C>T | COSN4705624 | PD3851a | [breast][NS][carcinoma][ductal_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1827 |
tgcaagctCTGCCTCctgg |
0 | UGAGGCAG | m7b | Created | no TS | -0.114000 |
-0.460000 |
hsa-miR-25-5p |
tgcaagCTCCGCCTcctgg |
0 | AGGCGGAG | m8a | Disrupted | -0.202000 | no TS |
-0.100000 |
hsa-miR-3612 |
tgcaagctcTGCCTCCTgg |
0 | AGGAGGCA | m8a | (m7a->m8a) | no TS | -0.108000 |
0.400000 |
hsa-miR-650 |
tgcaagctcTGCCTCCTgg |
0 | AGGAGGCA | m8a | (m7a->m8a) | no TS | -0.098000 |
-2.050000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
27547652 | rs190662972 | A | G |
hsa-miR-4683 |
1 |
ggtctcGATCTCC |
Created |
N |
-0.067 |
A |
hsa-miR-3672 hsa-miR-4461 hsa-miR-4786-5p hsa-miR-5186 hsa-miR-6864-3p hsa-miR-769-5p |
1 1 1 1 1 1 |
gGTCTCAAtctcc ggTCTCAATctcc GGTCTCAatctcc ggtctCAATCTCc gGTCTCAAtctcc GGTCTCAatctcc |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N |
-0.045 0.015 -0.13 -0.042 -0.045 -0.091 |