SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_000222
Gene Symbol: KIT
Description: Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT), transcript variant 1, mRNA.
Gene Location: chr4(+):55524094-55606881
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr4:g.54738722C>T COSN6834893 RK119_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-425-5p tttTGTCATTagccaccat
 0 AAUGACAC m7a (m6a->m7a) NA NA No effect
hsa-miR-4502 ttttgTCATCAGCcaccat
 11
 GCUGAUGA m8a Disrupted -0.218000 -0.126000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr4:g.54738754T>C COSN9792384 C0012T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-let-7f-2-3p ttccaaCTGTATAtattcc
 6
 CUAUACAG m7b Disrupted -0.164000 -0.027000 1.190000
hsa-miR-1185-1-3p ttccaaCTGTATATattcc
 6
 AUAUACAG m8a Disrupted -0.183000 -0.046000 0.430000
hsa-miR-1185-2-3p ttccaaCTGTATATattcc
 6
 AUAUACAG m8a Disrupted -0.173000 -0.036000 0.050000
hsa-miR-5011-5p ttccaactgTATATATtcc
 13
 UAUAUAUA m7b (m7b->m6c) 0.070000 0.022000 3.320000
hsa-miR-582-5p ttccAACTGTAtatattcc
 9
 UUACAGUU m7b Disrupted -0.136000 no TS 2.810000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.54738793G>A cosmic_v64_1760544 Leukemia/T-ALL
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-129-5p ccatgaaCAAAAAacattc
 0 CUUUUUGC m6b Created 0.091 0.131 -2.83
hsa-miR-26b-3p ccatGAACAGaaaacattc
 0 CCUGUUCU m6b Disrupted -0.105 no TS No effect
hsa-miR-375 ccatGAACAAAaaacattc
 0 UUUGUUCG m7a Created -0.081 -0.164 -0.16
hsa-miR-4652-3p ccatgAACAGAAaacattc
 0 GUUCUGUU m7b Disrupted -0.256 -0.102 No effect

Mutation Mutation ID Sample Name Cancer Type
chr4:g.54739212C>A COSN2033963 RK027_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1321 aaggCCTCCCTagccagca
 0 CAGGGAGG m7b Disrupted -0.181000 no TS 2.300000
hsa-miR-149-3p aaggCCTCCCTagccagca
 0 AGGGAGGG m7a Disrupted NA NA 0.030000
hsa-miR-3162-5p aaggcCTCCCTAgccagca
 0 UUAGGGAG m7b Disrupted -0.027000 no TS No effect
hsa-miR-4443 aagGCCTCCAtagccagca
 0 UUGGAGGC m7b (m6b->m7b) no TS -0.144000 -0.590000
hsa-miR-4739 aaggCCTCCCTagccagca
 0 AAGGGAGG m7b Disrupted -0.170000 no TS 0.010000
hsa-miR-4756-5p aaggCCTCCCTagccagca
 0 CAGGGAGG m7b Disrupted -0.244000 no TS 5.040000
hsa-miR-4802-5p aaggCCTCCATAgccagca
 0 UAUGGAGG m8a Created no TS -0.185000 -0.900000
hsa-miR-1321 aaggCCTCCCTagccagca
 0 CAGGGAGG m7b Disrupted -0.181 no TS 2.3
hsa-miR-149-3p aaggCCTCCCTagccagca
 0 AGGGAGGG m7a Disrupted NA NA 0.03
hsa-miR-3162-5p aaggcCTCCCTAgccagca
 0 UUAGGGAG m7b Disrupted -0.027 no TS No effect
hsa-miR-4443 aagGCCTCCAtagccagca
 0 UUGGAGGC m7b (m6b->m7b) no TS -0.144 -0.59
hsa-miR-4739 aaggCCTCCCTagccagca
 0 AAGGGAGG m7b Disrupted -0.17 no TS 0.01
hsa-miR-4756-5p aaggCCTCCCTagccagca
 0 CAGGGAGG m7b Disrupted -0.244 no TS 5.04
hsa-miR-4802-5p aaggCCTCCATAgccagca
 0 UAUGGAGG m8a Created no TS -0.185 -0.9

Mutation Mutation ID Sample Name Cancer Type
chr4:g.54739408G>T COSN7640469 PCSI_0164_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4698 caaagcaCATTTTGAacaa
 0 UCAAAAUG m8a Created no TS 0.052000 -0.420000
hsa-miR-5008-3p caaAGCACAGtttgaacaa
 5
 CCUGUGCU m7b (m7b->m6b) -0.170000 no TS No effect
hsa-miR-548g-3p caaagcACAGTTTgaacaa
 1
 AAAACUGU m7b Disrupted 0.001000 no TS 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.54739442T>G COSN7640470 PCSI_0218_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-148a-5p ctgatGAACTTattctgta
 3
 AAAGUUCU m6b Disrupted 0.002000 no TS No effect


Mutation Mutation ID Sample Name Cancer Type
chr4:g.54739468C>A COSN9045057 AOCS-131-1-3 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr4:g.54739641A>G cosmic_v64_1760522 Leukemia/T-ALL
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4783-3p gtcctggaCACCGGGccag
 0 CCCCGGUG m7b Disrupted -0.179 no TS 0.54

Mutation Mutation ID Sample Name Cancer Type
chr4:g.54739819G>C COSN9045058 AOCS-094-1-1 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-671-5p ttaccagaaGCTTCCatag
 0 AGGAAGCC m6b Disrupted -0.575000 -0.512000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr4:g.54740088C>A COSN2033964 RK182_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3941 aaaTGTGTAAatggcagag
 16
 UUACACAC m7a (m6a->m7a) -0.186000 -0.206000 -0.020000
hsa-miR-4659a-5p aaatgtgtaCATGGCAGag
 5
 CUGCCAUG m8a (m8a->m7b) -0.151000 no TS 0.342000
hsa-miR-4659b-5p aaatgtgtaCATGGCAgag
 5
 UUGCCAUG m7b (m7b->m6c) -0.151000 no TS 0.350000
hsa-miR-4672 aaaTGTGTAAatggcagag
 16
 UUACACAG m7a (m6a->m7a) -0.254000 -0.272000 No effect


Mutation Mutation ID Sample Name Cancer Type
chr4:g.54740256G>T COSN8491134 J80_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr4:g.54740257G>T COSN8491135 J80_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-21-3p agatttTGGTGTTGtgttg
 6
 CAACACCA m8a Created -0.176000 -0.335000 -0.020000
hsa-miR-3591-3p agatttTGGTGTTgtgttg
 6
 AAACACCA m7b Created -0.167000 -0.317000 -1.770000
hsa-miR-5003-5p agattttggTGTTGTGttg
 0 UCACAACA m7b (m6c->m7b) no TS -0.077000 -1.780000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.54740391A>G cosmic_v64_1760535 Leukemia/T-ALL
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3616-5p gggCACTTCATtgagagtt
 10
 AUGAAGUG m8a Disrupted -0.19 -0.086 0.15
hsa-miR-573 gggCACTTCAttgagagtt
 10
 CUGAAGUG m7b (m7b->m6b) -0.19 -0.096 0.03

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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