SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_018012
Gene Symbol: KIF26B
Description: Homo sapiens kinesin family member 26B (KIF26B), mRNA.
Gene Location: chr1(+):245318286-245866428
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr1:g.245702637C>T COSN14654131 PCSI_0090_Pa_X [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1909-3p gtggtCCCCTGCtccccag
0 CGCAGGGG m7b Created no TS -0.208000 -19.370000
hsa-miR-3144-5p gtGGTCCCCTgctccccag
0 AGGGGACC m8a (m7a->m8a) -0.247000 -0.275000 -0.950000
hsa-miR-4781-5p gtggtcCCCCGCTccccag
2
UAGCGGGG m7b Disrupted -0.260000 no TS 1.150000
hsa-miR-1909-3p gtggtCCCCTGCtccccag
0 CGCAGGGG m7b Created no TS -0.208000 -19.370000
hsa-miR-3144-5p gtGGTCCCCTgctccccag
0 AGGGGACC m8a (m7a->m8a) -0.247000 -0.275000 -0.950000
hsa-miR-4781-5p gtggtcCCCCGCTccccag
2
UAGCGGGG m7b Disrupted -0.260000 no TS 1.150000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.245702741G>A COSN1101435 BN24T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-365a-3p ggagcGGGCATTgagcgga
0 UAAUGCCC m7b Created no TS -0.118000 -0.300000
hsa-miR-365b-3p ggagcGGGCATTgagcgga
0 UAAUGCCC m7b Created no TS -0.118000 -0.300000
hsa-miR-365a-3p ggagcGGGCATTgagcgga
0 UAAUGCCC m7b Created no TS -0.118 -0.3
hsa-miR-365b-3p ggagcGGGCATTgagcgga
0 UAAUGCCC m7b Created no TS -0.118 -0.3

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table

Location SNP ID Ancestral
Allele
Allele miR ID Conservation miRSite FuncClass Validation context+
score change
245702638 rs140626338 G G hsa-miR-1343-5p
hsa-miR-4781-5p
hsa-miR-6090
hsa-miR-939-5p
18
18
18
18
tcccccGCTCCCC
tcCCCCGCTcccc
tccccCGCTCCCc
tcccccGCTCCCC
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
-0.248
-0.26
-0.202
-0.241
A hsa-miR-1275
hsa-miR-1296-3p
hsa-miR-4447
hsa-miR-4472
hsa-miR-4481
hsa-miR-4525
hsa-miR-4665-5p
hsa-miR-4723-5p
hsa-miR-4745-5p
hsa-miR-5010-5p
hsa-miR-5698
hsa-miR-625-5p
hsa-miR-6870-5p
hsa-miR-7111-5p
18
18
18
18
18
18
18
18
18
18
18
18
18
18
TCCCCCActcccc
tcCCCCACTcccc
tCCCCCACtcccc
tCCCCCACtcccc
tccCCCACTCccc
TCCCCCActcccc
TCCCCCActcccc
TCCCCCActcccc
tccCCCACTCccc
TCCCCCActcccc
TCCCCCActcccc
TCCCCCActcccc
TCCCCCActcccc
TCCCCCActcccc
Created
Created
Created
Created
Created
Created
Created
Created
Created
Created
Created
Created
Created
Created
N
N
N
N
N
N
N
N
N
N
N
N
N
N
-0.167
-0.177
-0.193
-0.193
-0.12
-0.167
-0.167
-0.163
-0.148
-0.174
-0.163
-0.171
-0.163
-0.184

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