SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_031954
Gene Symbol: KCTD10
Description: Homo sapiens potassium channel tetramerisation domain containing 10 (KCTD10), mRNA.
Gene Location: chr12(-):109886459-109915155
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr12:g.109448690C>T COSN1141756 HX13T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr12:g.109449101T>A COSN5929985 RK070_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4762-5p gcccaAGATTTGGtaaaga
 7
 CCAAAUCU m8a Disrupted -0.075000 no TS 3.550000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.109449634G>C ICGC_871A02F8-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4722-5p agcgattCTCCTGCCtcag
 0 GGCAGGAG m8a Created -0.101 -0.172 -0.26
hsa-miR-4768-3p agcgatTCTCCTGcctcag
 0 CCAGGAGA m7b Created -0.134 -0.135 -1.58
hsa-miR-922 agcgatTCTGCTGCctcag
 0 GCAGCAGA m8a Disrupted -0.012 no TS 0.01
hsa-miR-940 agcgattctCCTGCCTcag
 0 AAGGCAGG m7b (m6b->m7b) 0.02 -0.066 -0.01

Mutation Mutation ID Sample Name Cancer Type
chr12:g.109449751A>G COSN8694245 AOCS-166-1-2 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3119 ggaaaatggAAAAGCCAtt
 13
 UGGCUUUU m8a (m8a->m7a) -0.033000 -0.010000 -0.350000
hsa-miR-3160-5p ggaaaatggGAAAGCCatt
 0 GGCUUUCU m7a (m6a->m7a) NA NA -0.140000
hsa-miR-587 ggaaaATGGAAAagccatt
 12
 UUUCCAUA m7a Disrupted 0.040000 no TS 0.010000


Mutation Mutation ID Sample Name Cancer Type
chr12:g.109451132A>G COSN1556946 RK166_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr12:g.109451239G>T COSN6613052 CHC433T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr12:g.109451540A>G COSN2381445 TCGA-D1-A17A-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-103a-3p tgccgTGCTGCacccagat
 0 AGCAGCAU m6b Created no TS -0.109000 -4.480000
hsa-miR-107 tgccgTGCTGCacccagat
 0 AGCAGCAU m6b Created no TS -0.109000 -4.610000
hsa-miR-3944-5p tgccgtGCTGCACccagat
 0 UGUGCAGC m7b Created no TS -0.159000 -3.420000
hsa-miR-4455 tgccgtgctACACCCagat
 2
 AGGGUGUG m6b Disrupted -0.099000 no TS 2.990000
hsa-miR-5682 tgccGTGCTACacccagat
 4
 GUAGCACC m7a Disrupted -0.047000 -0.047000 2.510000
hsa-miR-609 tgccgtgctACACCCagat
 2
 AGGGUGUU m6b Disrupted -0.125000 no TS 1.160000
hsa-miR-103a-3p tgccgTGCTGCacccagat
 0 AGCAGCAU m6b Created no TS -0.109000 -4.480000
hsa-miR-107 tgccgTGCTGCacccagat
 0 AGCAGCAU m6b Created no TS -0.109000 -4.610000
hsa-miR-3944-5p tgccgtGCTGCACccagat
 0 UGUGCAGC m7b Created no TS -0.159000 -3.420000
hsa-miR-4455 tgccgtgctACACCCagat
 2
 AGGGUGUG m6b Disrupted -0.099000 no TS 2.990000
hsa-miR-5682 tgccGTGCTACacccagat
 4
 GUAGCACC m7a Disrupted -0.047000 -0.047000 2.510000
hsa-miR-609 tgccgtgctACACCCagat
 2
 AGGGUGUU m6b Disrupted -0.125000 no TS 1.160000
hsa-miR-103a-3p tgccgTGCTGCacccagat
 0 AGCAGCAU m6b Created no TS -0.109 -4.48
hsa-miR-107 tgccgTGCTGCacccagat
 0 AGCAGCAU m6b Created no TS -0.109 -4.61
hsa-miR-3944-5p tgccgtGCTGCACccagat
 0 UGUGCAGC m7b Created no TS -0.159 -3.42
hsa-miR-4455 tgccgtgctACACCCagat
 0 AGGGUGUG m6b Disrupted -0.099 no TS 2.99
hsa-miR-5682 tgccGTGCTACacccagat
 0 GUAGCACC m7a Disrupted -0.047 -0.047 2.51
hsa-miR-609 tgccgtgctACACCCagat
 0 AGGGUGUU m6b Disrupted -0.125 no TS 1.16

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
109449631 rs143893351 G G hsa-miR-1827
hsa-miR-4649-3p
hsa-miR-922
2
2
1
 tctgCTGCCTCAg
tctgctGCCTCAG
TCTGCTGcctcag
 Disrupted
Disrupted
Disrupted
N
N
N
 -0.09
-0.027
-0.012
A hsa-let-7a-5p
hsa-let-7b-5p
hsa-let-7c-5p
hsa-let-7d-5p
hsa-let-7e-5p
hsa-let-7f-5p
hsa-let-7g-5p
hsa-let-7i-5p
hsa-miR-202-3p
hsa-miR-4458
hsa-miR-4500
hsa-miR-7162-3p
hsa-miR-98-5p
2
2
2
2
2
2
2
2
2
2
2
2
2
 tctgCTACCTCAg
tctgCTACCTCAg
tctgCTACCTCAg
tctgCTACCTCAg
tctgCTACCTCAg
tctgCTACCTCAg
tctgCTACCTCAg
tctgCTACCTCAg
tctgcTACCTCAg
tctgCTACCTCAg
tctgCTACCTCAg
tctgctACCTCAG
tctgCTACCTCAg
 Created
Created
Created
Created
Created
Created
Created
Created
Created
Created
Created
Created
Created
N
N
N
N
N
N
N
N
N
N
N
N
N
 -0.065
-0.065
-0.065
-0.075
-0.065
-0.065
-0.065
-0.065
-0.005
-0.086
-0.086
-0.02
-0.065
109450353 rs192251818 C C hsa-miR-128-1-5p
hsa-miR-128-2-5p
hsa-miR-1909-3p
hsa-miR-6510-5p
hsa-miR-6722-3p
0 ggCGGCCCCtgct
ggCGGCCCCtgct
ggcggCCCCTGCt
ggcggcCCCTGCT
ggcggCCCCTGCt
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
 -0.066
-0.066
0.03
0.105
0.049
T hsa-miR-4722-5p
hsa-miR-6165
hsa-miR-6746-3p
2
2
0
 ggcggCTCCTGCt
ggcggcTCCTGCT
GGCGGCTcctgct
 Created
Created
Created
N
N
N
 0.05
0.152
-0.141

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