SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_021161 |
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Gene Symbol: | KCNK10 |
Description: | Homo sapiens potassium channel, subfamily K, member 10 (KCNK10), transcript variant 1, mRNA. |
Gene Location: | chr14(-):88646451-88793256 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr14:g.88180788T>C | COSN1665561 | RK056_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-199a-5p |
ataccttCACTGGacttca |
7 |
CCCAGUGU | m6b | Created | -0.049000 | -0.115000 | No effect | |
hsa-miR-199b-5p |
ataccttCACTGGacttca |
7 |
CCCAGUGU | m6b | Created | -0.049000 | -0.118000 |
-0.050000 |
|
hsa-miR-5190 |
atacctTCACTGGacttca |
0 | CCAGUGAC | m7a | Created | NA | NA |
-0.110000 |
|
hsa-miR-199a-5p |
ataccttCACTGGacttca |
0 | CCCAGUGU | m6b | Created | -0.049 | -0.115 | No effect | |
hsa-miR-199b-5p |
ataccttCACTGGacttca |
0 | CCCAGUGU | m6b | Created | -0.049 | -0.118 |
-0.05 |
|
hsa-miR-5190 |
atacctTCACTGGacttca |
0 | CCAGUGAC | m7a | Created | NA | NA |
-0.11 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr14:g.88181062T>G | COSN15083325 | LP6007422-DNA_A01 | [oesophagus][NS][carcinoma][adenocarcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-141-3p |
agcCAGTGTTgcattccac |
0 | UAACACUG | m7b | (m7b->m6c) | 0.016000 | no TS |
2.520000 |
|
hsa-miR-200a-3p |
agcCAGTGTTgcattccac |
0 | UAACACUG | m7b | (m7b->m6c) | 0.016000 | no TS |
4.140000 |
|
hsa-miR-3064-3p |
agccagTGTGGCAttccac |
1 |
UUGCCACA | m7b | Created | -0.212000 | -0.276000 |
-0.050000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr14:g.88181093G>C | COSN8460962 | AOCS-078-1-9 | [ovary][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1303 |
agagcccCTCTAAAacgag |
2 |
UUUAGAGA | m7a | Created | 0.070000 | 0.106000 | No effect | |
hsa-miR-3184-5p |
agaGCCCCTCtaaaacgag |
0 | UGAGGGGC | m7b | (m6c->m7b) | no TS | -0.205000 |
-6.320000 |
|
hsa-miR-423-5p |
agaGCCCCTCtaaaacgag |
0 | UGAGGGGC | m7b | (m6c->m7b) | no TS | -0.196000 | No effect | |
hsa-miR-5095 |
agagccCCTGTAAaacgag |
2 |
UUACAGGC | m7a | Disrupted | 0.001000 | no TS |
3.520000 |
|
hsa-miR-877-5p |
agagccCCTCTAaaacgag |
1 |
GUAGAGGA | m6b | Created | 0.003000 | -0.030000 |
-0.010000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr14:g.88181415G>A | COSN15339437 | SNU_WGS_02_S1 | [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-147a |
cacacacaCACACACatac |
0 | GUGUGUGG | m7a | Created | 0.023000 | 0.023000 |
-0.020000 |
|
hsa-miR-147b |
cacacacaCGCACACatac |
0 | GUGUGCGG | m7a | Disrupted | NA | NA |
0.130000 |
|
hsa-miR-210 |
cacacacACGCACAcatac |
0 | CUGUGCGU | m7b | Disrupted | -0.064000 | no TS |
2.620000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr14:g.88181419A>G | COSN15610208 | C0012T | [kidney][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-147a |
cacacaCACACACgcacac |
0 | GUGUGUGG | m7a | Disrupted | 0.023000 | 0.023000 |
0.120000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr14:g.88181927G>C | COSN8460963 | AOCS-166-1-2 | [ovary][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr14:g.88182680T>C | COSN6263739 | RK308_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-154-5p |
aacATAACCTtgggctggg |
4 |
UAGGUUAU | m7b | (m7b->m6c) | 0.090000 | no TS |
0.190000 |
|
hsa-miR-1915-3p |
aacataaCCCTGGGctggg |
0 | CCCCAGGG | m7b | Created | -0.162000 | -0.188000 |
-0.010000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr14:g.88183941C>A | COSN5210835 | SS6003323 | [oesophagus][NS][carcinoma][adenocarcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-302b-5p |
taccttTTAAAGagttcac |
4 |
ACUUUAAC | m6b | Created | 0.185000 | 0.352000 | No effect | |
hsa-miR-302d-5p |
taccttTTAAAGagttcac |
4 |
ACUUUAAC | m6b | Created | 0.185000 | 0.359000 | No effect | |
hsa-miR-3607-3p |
tacctTTTACAGagttcac |
14 |
ACUGUAAA | m7b | Disrupted | 0.030000 | -0.149000 |
0.060000 |
|
hsa-miR-3664-5p |
taccttttACAGAGTTcac |
1 |
AACUCUGU | m8a | Disrupted | 0.013000 | no TS |
0.660000 |
|
hsa-miR-3686 |
taccttTTACAGAgttcac |
13 |
AUCUGUAA | m7b | Disrupted | -0.047000 | -0.115000 |
0.800000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr14:g.88184956G>A | COSN8460964 | AOCS-114-1-8 | [ovary][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-2115-5p |
ttgtTGGAAGCagatcaga |
11 |
AGCUUCCA | m7b | Disrupted | -0.275000 | no TS |
0.010000 |
|
hsa-miR-4686 |
ttgttggaAGCAGATcaga |
0 | UAUCUGCU | m7b | Disrupted | -0.024000 | 0.073000 |
6.620000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr14:g.88185284G>A | COSN8460965 | AOCS-116-1-3 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4435 |
gttCTGGCCATacatgtta |
0 | AUGGCCAG | m8a | Created | -0.022000 | -0.236000 |
-0.010000 |
hsa-miR-548s |
gttcTGGCCATacatgtta |
0 | AUGGCCAA | m7a | Created | -0.074000 | -0.074000 |
-0.030000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
88180504 | rs182857150 | C | C |
hsa-miR-6886-5p |
2 |
taaCTGCGGAagc |
Disrupted |
N |
-0.199 |
T |
hsa-miR-2115-5p hsa-miR-3692-3p |
1 2 |
taactgTGGAAGC taacTGTGGAAgc |
Created Created |
N N |
-0.148 -0.103 |
|||
88181096 | rs186714073 | C | C |
hsa-miR-4283 hsa-miR-5095 hsa-miR-6085 hsa-miR-6813-5p hsa-miR-7151-3p |
2 2 2 2 2 |
aGAGCCCCtgtaa agagccCCTGTAA agAGCCCCTgtaa agAGCCCCTgtaa agagccCCTGTAA |
Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N |
-0.223 0.001 -0.133 -0.152 -0.009 |
T |
hsa-miR-2467-5p hsa-miR-4797-5p |
2 2 |
aGAGCCTCtgtaa agagcCTCTGTAa |
Created Created |
N N |
-0.147 -0.013 |
|||
88182157 | rs184463086 | G | G |
hsa-miR-130b-5p hsa-miR-3124-3p hsa-miR-3180-5p hsa-miR-665 |
2 3 2 2 |
ttcctgGAAAGAG ttcctGGAAAGAg ttcCTGGAAAgag tTCCTGGAaagag |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
0.118 0.107 0.051 -0.009 |
T |
hsa-miR-4700-3p hsa-miR-5095 hsa-miR-7151-3p |
2 2 2 |
tTCCTGTAaagag ttCCTGTAAagag ttCCTGTAAagag |
Created Created Created |
N N N |
0.002 0.035 0.028 |