SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_004972 |
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Gene Symbol: | JAK2 |
Description: | Homo sapiens Janus kinase 2 (JAK2), mRNA. |
Gene Location: | chr9(+):4985244-5128183 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.5127064G>A | COSN1379015 | HCC51T | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-129-5p |
ctgGCAAAAAaaaaaaaat |
0 | CUUUUUGC | m7b | (m6b->m7b) | no TS | -0.108000 |
-0.240000 |
|
hsa-miR-129-5p |
ctgGCAAAAAaaaaaaaat |
0 | CUUUUUGC | m7b | (m6b->m7b) | no TS | -0.108 |
-0.24 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.5127339G>C | COSN9318389 | J52_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3185 |
tgtgtcCTTCTTCatttat |
9 |
AGAAGAAG | m7b | Created | -0.049000 | -0.199000 |
-0.690000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr9:g.5127566A>T | COSN9713007 | AOCS-122-1-4 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-587 |
tgttttttaTATGGAActa |
0 | UUUCCAUA | m7b | (m6c->m7b) | no TS | -0.097000 |
-1.850000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
5126913 | rs41314565 | G | |||||||
A |
hsa-miR-129-5p hsa-miR-130a-5p hsa-miR-153-5p hsa-miR-23a-3p hsa-miR-23b-3p hsa-miR-23c hsa-miR-6885-3p |
10 5 9 5 5 5 11 |
aGCAAAAAtgtga agcaaaAATGTGA agcAAAAATGtga agcaaaAATGTGA agcaaaAATGTGA agcaaaAATGTGA AGCAAAAatgtga |
Created Created Created Created Created Created Created |
N N N N N N N |
-0.083 -0.189 0.021 -0.181 -0.181 -0.181 -0.067 |
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5127687 | rs115158615 | A | |||||||
A |
hsa-miR-3185 hsa-miR-4709-3p hsa-miR-5186 |
0 |
TTCTTCAatctct tTCTTCAAtctct ttcttCAATCTCt |
Disrupted Disrupted Disrupted |
N N N |
-0.011 -0.04 -0.153 |