SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001079818
Gene Symbol: ITGA6
Description: Homo sapiens integrin, alpha 6 (ITGA6), transcript variant 2, mRNA.
Gene Location: chr2(+):173292313-173371181
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr2:g.172504511C>T COSN6154609 RK308_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-449b-3p tatttttggTGTGGCTGac
0 CAGCCACA m8a (m7b->m8a) no TS -0.152000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.172506170T>G COSN9866734 C0100T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1260a ataaaaGTGGGAaataaat
0 AUCCCACC m6b Created no TS -0.207000 -4.080000
hsa-miR-1260b ataaaaGTGGGAaataaat
0 AUCCCACC m6b Created no TS -0.207000 No effect
hsa-miR-188-3p ataaaaGTGGGAaataaat
0 CUCCCACA m6b Created no TS -0.199000 -4.710000
hsa-miR-205-3p ataaaagtgTGAAATaaat
15
GAUUUCAG m6b Disrupted -0.027000 no TS No effect
hsa-miR-3156-3p ataaaAGTGGGAaataaat
0 CUCCCACU m7b Created no TS -0.489000 -7.860000
hsa-miR-377-3p ataaaaGTGTGAaataaat
10
AUCACACA m6b Disrupted -0.345000 -0.178000 No effect
hsa-miR-4301 ataaaAGTGGGAaataaat
0 UCCCACUA m7a Created no TS -0.225000 -1.920000
hsa-miR-4446-5p ataaaagtGGGAAATaaat
0 AUUUCCCU m7a Created NA NA -7.010000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.172506205G>A COSN15041785 LP6007422-DNA_A01 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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