SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_001134222
Gene Symbol:	IRX2
Description:	Homo sapiens iroquois homeobox 2 (IRX2), transcript variant 2, mRNA.
Gene Location:	chr5(-):2746278-2751769
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr5:g.2746468G>T			ICGC_sm6041		RK001_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1228-3p	tattctatAGGTGTGAtag	0	UCACACCU	m8a	Disrupted	-0.39	no TS	3.89
hsa-miR-377-3p	tattctataTGTGTGATag	0	AUCACACA	m8a	(m7a->m8a)	-0.188	-0.413	0.06
hsa-miR-4789-3p	tattctaTATGTGTGatag	0	CACACAUA	m8a	Created	-0.063	-0.237	-0.61

Mutation			Mutation ID		Sample Name		Cancer Type
chr5:g.2746548A>G			ICGC_sm81582		RK010_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4789-3p	ccccgatgTATGTGTGact	0	CACACAUA	m8a	Disrupted	-0.063	no TS	-0.79
hsa-miR-603	ccccgatgtGTGTGTGact	0	CACACACU	m7a	(m6a->m7a)	NA	NA	-5.53

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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