SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001031853
Gene Symbol: INSC
Description: Homo sapiens inscuteable homolog (Drosophila) (INSC), transcript variant 1, mRNA.
Gene Location: chr11(+):15133969-15268754
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr11:g.15246373A>G COSN14637885 PCSI_0072_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-148a-5p cattttttAGAACTTTgga
0 AAAGUUCU m8a Created no TS -0.102000 -0.060000
hsa-miR-3168 catttttTAGAACTttgga
0 GAGUUCUA m7b Created no TS -0.159000 -3.340000
hsa-miR-4799-5p catttTTTAGAactttgga
0 AUCUAAAU m6b Created no TS 0.008000 -5.270000
hsa-miR-561-3p cattttttaAAACTTTGga
3
CAAAGUUU m8a (m8a->m7b) -0.004000 0.019000 0.200000
hsa-miR-148a-5p cattttttAGAACTTTgga
0 AAAGUUCU m8a Created no TS -0.102000 -0.060000
hsa-miR-3168 catttttTAGAACTttgga
0 GAGUUCUA m7b Created no TS -0.159000 -3.340000
hsa-miR-4799-5p catttTTTAGAactttgga
0 AUCUAAAU m6b Created no TS 0.008000 -5.270000
hsa-miR-561-3p cattttttaAAACTTTGga
3
CAAAGUUU m8a (m8a->m7b) -0.004000 0.019000 0.200000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.15246751T>A COSN8941352 SS6003314 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-371a-5p ttgctTTTGAGTaacctcc
0 ACUCAAAC m7a Created NA NA -0.190000
hsa-miR-371b-5p ttgcTTTTGAGTaacctcc
0 ACUCAAAA m8a Created no TS 0.023000 -0.420000
hsa-miR-373-5p ttgcTTTTGAGTaacctcc
0 ACUCAAAA m8a Created no TS 0.023000 -0.550000
hsa-miR-466 ttgctttTGTGTAacctcc
2
AUACACAU m6b Disrupted -0.169000 -0.140000 0.040000
hsa-miR-4731-3p ttgcttTTGTGTaacctcc
2
CACACAAG m6b Disrupted -0.146000 -0.130000 0.163000
hsa-miR-4801 ttgcttTTGTGTAacctcc
2
UACACAAG m7a Disrupted -0.149000 -0.130000 0.010000
hsa-miR-616-5p ttgcTTTTGAGTaacctcc
0 ACUCAAAA m8a Created no TS 0.014000 -0.430000
hsa-miR-888-5p ttgctTTTGAGTAacctcc
0 UACUCAAA m8a Created no TS -0.124000 -1.722000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.15246816C>G 13_53 SJMB008_D Medulloblastoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-766-5p gattgaTTCCTCCTcaaaa
0 AGGAGGAA m8a Disrupted -0.176 no TS 5.47

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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