| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_003866 |
|---|---|
| Gene Symbol: | INPP4B |
| Description: | Homo sapiens inositol polyphosphate-4-phosphatase, type II, 105kDa (INPP4B), transcript variant 2, mRNA. |
| Gene Location: | chr4(-):142949181-143767604 |
| Browse Associations | |
| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr4:g.142028173G>T | COSN15003628 | LP6007414-DNA_A02 | [oesophagus][NS][carcinoma][adenocarcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3680-5p |
atgcatggAGTGAGTaaag |
0 | GACUCACU | m7b | Disrupted | -0.309000 | no TS |
2.660000 |
|
| hsa-miR-4798-3p |
atgcatggaGTGAGTaaag |
0 | AACUCACG | m6b | Disrupted | -0.166000 | no TS |
0.090000 |
|
| hsa-miR-888-5p |
atgcatggaTTGAGTAaag |
0 | UACUCAAA | m7a | (m6a->m7a) | no TS | -0.063000 |
-2.280000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr4:g.142028233A>G | COSN6803669 | RK053_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-136-3p |
atgttccaCGATGATctct |
0 | CAUCAUCG | m7b | Created | no TS | -0.166000 |
-4.600000 |
|
| hsa-miR-3190-3p |
atgTTCCACAatgatctct |
2 |
UGUGGAAG | m7a | (m7a->m6b) | -0.121000 | no TS |
0.890000 |
|
| hsa-miR-4289 |
atgttcCACAATGatctct |
2 |
GCAUUGUG | m7b | Disrupted | -0.242000 | no TS |
1.250000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr4:g.142028255G>A | COSN7740319 | 8016470 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-4797-3p |
aaTACTGAGAcagtttgca |
2 |
UCUCAGUA | m8a | (m7b->m8a) | -0.152000 | -0.302000 |
-0.100000 |
|
| hsa-miR-548av-3p |
aatactgagGCAGTTTgca |
3 |
AAAACUGC | m7b | (m7b->m6b) | -0.082000 | no TS |
3.210000 |
|
| hsa-miR-548g-3p |
aatactgagACAGTTTgca |
0 | AAAACUGU | m7b | (m6b->m7b) | no TS | -0.042000 |
-0.220000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr4:g.142028494G>C | COSN9216407 | AOCS-166-1-2 | [ovary][NS][other][neoplasm] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-200b-3p |
ttcattcatCAGTATTtaa |
0 | UAAUACUG | m7b | (m6b->m7b) | no TS | -0.187000 |
-3.082000 |
|
| hsa-miR-200c-3p |
ttcattcatCAGTATTtaa |
0 | UAAUACUG | m7b | (m6b->m7b) | no TS | -0.187000 |
-3.480000 |
|
| hsa-miR-429 |
ttcattcatCAGTATTtaa |
0 | UAAUACUG | m7b | (m6b->m7b) | no TS | -0.178000 |
-4.300000 |
|
| hsa-miR-4502 |
ttcatTCATCAGtatttaa |
0 | GCUGAUGA | m7b | Created | -0.209000 | -0.452000 |
-0.070000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr4:g.142028508T>C | COSN1995694 | RK067_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-4325 |
cacaAAGTGCAAatttcat |
0 | UUGCACUU | m8a | Created | no TS | -0.336000 |
-1.950000 |
|
| hsa-miR-507 |
cacaaaGTGCAAAtttcat |
0 | UUUUGCAC | m7b | Created | no TS | -0.220000 |
-1.950000 |
|
| hsa-miR-557 |
cacaaaGTGCAAAtttcat |
0 | GUUUGCAC | m7b | Created | no TS | -0.201000 |
-1.950000 |
|
| hsa-miR-4325 |
cacaAAGTGCAAatttcat |
0 | UUGCACUU | m8a | Created | no TS | -0.336 |
-1.95 |
|
| hsa-miR-507 |
cacaaaGTGCAAAtttcat |
0 | UUUUGCAC | m7b | Created | no TS | -0.22 |
-1.95 |
|
| hsa-miR-557 |
cacaaaGTGCAAAtttcat |
0 | GUUUGCAC | m7b | Created | no TS | -0.201 |
-1.95 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr4:g.142028528T>G | COSN9904737 | C0013T | [kidney][NS][other][neoplasm] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-136-5p |
ctagctgATGGAGattggt |
0 | ACUCCAUU | m6b | Created | no TS | -0.094000 |
-1.720000 |
|
| hsa-miR-216a |
ctagctgatTGAGATTggt |
2 |
UAAUCUCA | m7b | (m7b->m6b) | -0.114000 | no TS | No effect | |
| hsa-miR-34a-3p |
ctaGCTGATTGagattggt |
2 |
CAAUCAGC | m8a | Disrupted | -0.170000 | no TS |
1.530000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr4:g.142028546G>A | COSN1995695 | RK089_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-376c |
agctTCTATGTgttgagcc |
4 |
AACAUAGA | m7b | Disrupted | -0.130000 | no TS |
4.350000 |
|
| hsa-miR-4789-3p |
agcttcTATGTGTtgagcc |
1 |
CACACAUA | m7b | Disrupted | -0.116000 | -0.056000 |
3.600000 |
|
| hsa-miR-376c |
agctTCTATGTgttgagcc |
0 | AACAUAGA | m7b | Disrupted | -0.13 | no TS |
4.35 |
|
| hsa-miR-4789-3p |
agcttcTATGTGTtgagcc |
0 | CACACAUA | m7b | Disrupted | -0.116 | -0.056 |
3.6 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr4:g.142028596A>T | COSN15613943 | C0046T | [kidney][NS][other][neoplasm] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-548c-3p |
atccATTTTTaaaaatctt |
0 | CAAAAAUC | m6b | Created | no TS | 0.074000 |
-3.520000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr4:g.142028617G>A | COSN6803670 | RK212_C01 | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-3942-5p |
cagcaTATTGCTctgaaag |
2 |
AAGCAAUA | m7b | Disrupted | -0.145000 | no TS |
2.180000 |
| hsa-miR-4703-5p |
cagcaTATTGCTctgaaag |
2 |
UAGCAAUA | m7b | Disrupted | -0.127000 | no TS |
-1.610000 |
| hsa-miR-759 |
cagcatattACTCTGaaag |
8 |
GCAGAGUG | m6b | Created | -0.101000 | -0.250000 |
-1.440000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 142028060 | rs140178230 | - | - |
hsa-miR-382-3p hsa-miR-6885-3p |
2 1 |
aGAATGATAagcaaaac agaatgatAAGCAAAAc |
Unknown Unknown |
N N |
-0.126 -0.003 |
| GAT |
hsa-miR-136-3p |
1 |
agaatGATGATAagcaaaac |
Unknown |
N |
-0.157 |
|||
| 142028306 | rs35611846 | - | - |
hsa-miR-153-5p hsa-miR-4643 hsa-miR-466 hsa-miR-4789-3p |
1 1 1 1 |
aaAAAAATGtgta aaaaaaATGTGTA aaaaaaATGTGTA aaaaaaATGTGTA |
Unknown Unknown Unknown Unknown |
N N N N |
-0.005 0.002 0.003 0.002 |
| A | |||||||||
| 142028531 | rs138272803 | G | G |
hsa-miR-34a-3p hsa-miR-4705 hsa-miR-5690 |
2 1 2 |
ctaGCTGATTgag ctagcTGATTGAg cTAGCTGAttgag |
Disrupted Disrupted Disrupted |
N N N |
-0.17 -0.056 -0.11 |
| A |
hsa-miR-4275 |
1 |
ctagcTAATTGAg |
Created |
N |
-0.003 |
|||
| 142028548 | rs142574264 | A | A |
hsa-miR-376c-3p hsa-miR-4789-3p |
4 3 |
gctTCTATGTgtt gcttcTATGTGTt |
Disrupted Disrupted |
N N |
-0.13 -0.06 |