| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_016247 |
|---|---|
| Gene Symbol: | IMPG2 |
| Description: | Homo sapiens interphotoreceptor matrix proteoglycan 2 (IMPG2), mRNA. |
| Gene Location: | chr3(-):100941389-101039419 |
| Browse Associations | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr3:g.101222818A>G | COSN5515111 | RK040_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-136-3p |
tatgtGATGATacttaagc |
2 |
CAUCAUCG | m6b | Disrupted | -0.110000 | no TS |
1.230000 |
|
| hsa-miR-181c-3p |
tatgtGATGGTacttaagc |
0 | AACCAUCG | m6b | Created | no TS | -0.167000 |
-0.010000 |
|
| hsa-miR-624-5p |
tatgtgaTGGTACTtaagc |
0 | UAGUACCA | m7b | Created | no TS | -0.245000 |
-8.940000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr3:g.101222853A>T | COSN15436282 | AOCS-150-8-X | [ovary][NS][other][neoplasm] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-16-1-3p |
agagAATACTGGtataatt |
0 | CCAGUAUU | m8a | Created | no TS | -0.107000 |
-2.470000 |
|
| hsa-miR-3144-3p |
agagaatacAGGTATAatt |
0 | AUAUACCU | m7b | (m7b->m6b) | -0.343000 | -0.135000 |
5.760000 |
|
| hsa-miR-4742-3p |
agagAATACAGgtataatt |
3 |
UCUGUAUU | m7b | Disrupted | -0.095000 | no TS |
5.430000 |
|
| hsa-miR-630 |
agAGAATACTggtataatt |
5 |
AGUAUUCU | m8a | (m7b->m8a) | -0.166000 | -0.072000 |
1.830000 |
|
| hsa-miR-875-5p |
agagaatacAGGTATAatt |
0 | UAUACCUC | m7a | (m7a->m6a) | -0.150000 | no TS |
0.030000 |
|
| hsa-miR-16-1-3p |
agagAATACTGGtataatt |
0 | CCAGUAUU | m8a | Created | no TS | -0.107000 |
-2.470000 |
|
| hsa-miR-3144-3p |
agagaatacAGGTATAatt |
0 | AUAUACCU | m7b | (m7b->m6b) | -0.343000 | -0.135000 |
5.760000 |
|
| hsa-miR-4742-3p |
agagAATACAGgtataatt |
3 |
UCUGUAUU | m7b | Disrupted | -0.095000 | no TS |
5.430000 |
|
| hsa-miR-630 |
agAGAATACTggtataatt |
5 |
AGUAUUCU | m8a | (m7b->m8a) | -0.166000 | -0.072000 |
1.830000 |
|
| hsa-miR-875-5p |
agagaatacAGGTATAatt |
0 | UAUACCUC | m7a | (m7a->m6a) | -0.150000 | no TS |
0.030000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr3:g.101223196C>T | COSN7548242 | 8057783 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-591 |
atgatgtgATGGTCactat |
0 | AGACCAUG | m6b | Created | no TS | -0.124000 |
-0.010000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr3:g.101223355C>A | COSN5144104 | PD4115a | [breast][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1273g-5p |
acacaAACCACaaacgggt |
0 | GGUGGUUG | m6b | Created | no TS | -0.066000 | No effect | |
| hsa-miR-193b-5p |
acacAAACCCCaaacgggt |
2 |
CGGGGUUU | m7b | Disrupted | -0.190000 | no TS | No effect | |
| hsa-miR-3170 |
acacaAACCCCAaacgggt |
2 |
CUGGGGUU | m7b | Disrupted | -0.239000 | no TS | No effect | |
| hsa-miR-4260 |
acacaaaCCCCAAacgggt |
2 |
CUUGGGGC | m6b | Disrupted | -0.094000 | no TS | No effect | |
| hsa-miR-450a-3p |
acacaaaCCCCAAacgggt |
2 |
AUUGGGGA | m6b | Disrupted | -0.095000 | no TS |
0.010000 |
|
| hsa-miR-5087 |
acACAAACCCcaaacgggt |
1 |
GGGUUUGU | m8a | (m8a->m7b) | -0.092000 | -0.182000 |
0.010000 |
|
| hsa-miR-5572 |
acacaaACCCCAAacgggt |
2 |
GUUGGGGU | m7b | Disrupted | -0.248000 | no TS | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr3:g.101223638C>A | COSN6711042 | RK197_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-186-5p |
acaaatATTCTTTGtaggc |
0 | CAAAGAAU | m8a | Disrupted | 0.073000 | -0.005000 | No effect | |
| hsa-miR-520d-5p |
acaaatattCTTTGTAGgc |
0 | CUACAAAG | m8a | (m8a->m7a) | 0.106000 | 0.042000 | No effect | |
| hsa-miR-524-5p |
acaaatattCTTTGTAGgc |
0 | CUACAAAG | m8a | (m8a->m7a) | 0.091000 | 0.036000 | No effect | |
| hsa-miR-5692a |
acaaatATTATTTGtaggc |
1 |
CAAAUAAU | m8a | Created | 0.373000 | 0.486000 | No effect | |
| hsa-miR-5692b |
acaaATATTATTtgtaggc |
0 | AAUAAUAU | m8a | Created | 0.149000 | 0.227000 | No effect | |
| hsa-miR-5692c |
acaaATATTATTtgtaggc |
0 | AAUAAUAU | m8a | Created | 0.149000 | 0.227000 |
-0.010000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr3:g.101223819C>T | COSN6711043 | RK308_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-577 |
caggcTTTATCTgatttta |
0 | UAGAUAAA | m7b | Created | no TS | 0.113000 |
0.190000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr3:g.101224311G>T | COSN6425118 | HX26T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3607-3p |
tgtTTTACAGatgtagcct |
2 |
ACUGUAAA | m7b | (m7b->m6c) | 0.283000 | 0.143000 |
0.300000 |
|
| hsa-miR-3686 |
tgttTTACAGATgtagcct |
2 |
AUCUGUAA | m8a | Disrupted | 0.201000 | 0.186000 |
3.580000 |
|
| hsa-miR-4495 |
tgtTTTACATatgtagcct |
0 | AAUGUAAA | m7b | (m6c->m7b) | no TS | 0.201000 | No effect | |
| hsa-miR-5580-3p |
tgttttaCATATGTagcct |
0 | CACAUAUG | m7b | Created | no TS | 0.095000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr3:g.101224353A>T | COSN5805821 | EOPC-04_tumor | [prostate][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3143 |
cattttaaaAATGTTATta |
2 |
AUAACAUU | m8a | (m8a->m7a) | -0.005000 | -0.017000 |
-0.010000 |
|
| hsa-miR-543 |
cattttaaaAATGTTatta |
3 |
AAACAUUC | m6b | Disrupted | 0.089000 | no TS |
2.460000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr3:g.101225091A>G | COSN7548243 | 8036161 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-4700-3p |
tgtttTCCTGTactacgtg |
0 | CACAGGAC | m6b | Created | no TS | 0.007000 |
-0.520000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr3:g.101225728G>T | COSN1264089 | HCC123T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr3:g.101225952T>G | COSN4893519 | PCSI_0009_Pa_X | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3684 |
aatacctccGGTCTAAatt |
0 | UUAGACCU | m7a | (m6a->m7a) | no TS | -0.094000 |
-0.970000 |
|
| hsa-miR-4459 |
aataCCTCCTGtctaaatt |
2 |
CCAGGAGG | m7b | Disrupted | -0.051000 | 0.103000 |
-0.090000 |
|
| hsa-miR-4524b-3p |
aatacctCCTGTCTaaatt |
1 |
GAGACAGG | m7b | Disrupted | -0.289000 | -0.118000 |
0.010000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr3:g.101226155T>A | COSN9107378 | AOCS-130-1-0 | [ovary][NS][other][neoplasm] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3655 |
agtgtcggGACAAGacccc |
0 | GCUUGUCG | m6b | Created | no TS | -0.006000 |
-1.690000 |
|
| hsa-miR-4449 |
agtgtCGGGACaagacccc |
0 | CGUCCCGG | m6b | Created | no TS | -0.146000 |
-11.930000 |
|
| hsa-miR-4646-3p |
agtgtcGGGACAAgacccc |
0 | AUUGUCCC | m7b | Created | no TS | -0.058000 |
-9.730000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr3:g.101226898A>G | COSN8487787 | 783_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-154-3p |
atgtcaTATGATTaacctg |
2 |
AAUCAUAC | m7a | Created | -0.062000 | -0.062000 | No effect |
| hsa-miR-487a |
atgtcaTATGATTaacctg |
2 |
AAUCAUAC | m7a | Created | -0.041000 | -0.041000 |
-2.380000 |
| hsa-miR-5007-3p |
atgtCATATGATtaacctg |
0 | AUCAUAUG | m8a | Created | no TS | -0.198000 |
-1.960000 |
| hsa-miR-944 |
atgtcatATAATTaacctg |
7 |
AAAUUAUU | m6b | Disrupted | 0.370000 | 0.349000 |
0.550000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 101222643 | rs150973751 | A | A |
hsa-miR-4263 hsa-miR-4735-5p hsa-miR-576-5p hsa-miR-944 |
8 7 8 1 |
ataaTTAGAAAta atAATTAGAaata ataATTAGAAAta ATAATTAgaaata |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.062 -0.047 -0.277 0.01 |
| 101222848 | rs813449 | T | T |
hsa-miR-3144-3p hsa-miR-875-5p |
4 4 |
cAGGTATAAtttt cAGGTATAatttt |
Disrupted Disrupted |
N N |
-0.343 -0.15 |
| 101224287 | rs141519900 | T | T |
hsa-miR-410-3p |
0 |
gaaTTATATAcac |
Disrupted |
N |
0.16 |
| C |
hsa-miR-297 hsa-miR-379-3p hsa-miR-380-3p hsa-miR-411-3p hsa-miR-4495 hsa-miR-567 |
0 |
gaattACATACAc gaaTTACATAcac gaATTACATAcac gaaTTACATAcac gaaTTACATAcac gaattACATACAc |
Created Created Created Created Created Created |
N N N N N N |
-0.019 0.1 0.166 0.1 0.114 0.037 |
|||
| 101224311 | rs78391139 | G | G |
hsa-miR-3607-3p hsa-miR-3686 |
2 2 |
TTTACAGAtgtag tTTACAGAtgtag |
Disrupted Disrupted |
N N |
0.14 0.015 |
| T |
hsa-miR-379-3p hsa-miR-380-3p hsa-miR-411-3p hsa-miR-4495 hsa-miR-5580-3p |
2 2 2 2 3 |
tTTACATAtgtag tTTACATAtgtag tTTACATAtgtag TTTACATAtgtag tttaCATATGTAg |
Created Created Created Created Created |
N N N N N |
0.089 0.09 0.089 0.201 0.095 |
|||
| 101224316 | rs112670504 | T | T |
hsa-miR-3607-3p hsa-miR-3686 |
3 3 |
ggtgtTTTACAGA ggtgttTTACAGA |
Disrupted Disrupted |
N N |
0.14 0.015 |
| C |
hsa-miR-20b-3p hsa-miR-3137 hsa-miR-4773 |
3 3 1 |
ggtgttCTACAGA ggtgttCTACAGA ggTGTTCTAcaga |
Created Created Created |
N N N |
0.016 0.014 0.084 |
|||
| 101224669 | rs183226725 | C | C |
hsa-miR-124-5p hsa-miR-2116-5p hsa-miR-22-5p hsa-miR-4677-5p hsa-miR-892a |
2 2 2 2 2 |
gaaGAACACAgtt gAAGAACAcagtt GAAGAACAcagtt gAAGAACAcagtt gaagaACACAGTt |
Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N |
0.038 0.102 0.054 0.07 0.003 |
| T |
hsa-miR-4742-3p hsa-miR-630 |
2 2 |
gaagAATACAGtt gaAGAATACAgtt |
Created Created |
N N |
0.079 0.098 |
|||
| 101225323 | rs77631255 | C | C |
hsa-miR-4501 hsa-miR-6869-5p |
6 3 |
cctacTCACATAa cCTACTCAcataa |
Disrupted Disrupted |
N N |
0.028 0.052 |
| T |
hsa-miR-379-3p hsa-miR-380-3p hsa-miR-3924 hsa-miR-411-3p hsa-miR-4495 hsa-miR-562 |
6 6 6 6 6 3 |
cctacTTACATAa cctacTTACATAa cctactTACATAA cctacTTACATAa cctacTTACATAa cCTACTTAcataa |
Created Created Created Created Created Created |
N N N N N N |
0.112 0.117 0.121 0.112 0.125 0.076 |
|||
| 101225734 | rs149067584 | C | C |
hsa-miR-153-3p hsa-miR-25-3p hsa-miR-32-5p hsa-miR-363-3p hsa-miR-367-3p hsa-miR-448 hsa-miR-92a-3p hsa-miR-92b-3p |
4 5 5 5 5 3 5 5 |
caTATGCAAtagg cataTGCAATAgg cataTGCAATAgg cataTGCAATAgg cataTGCAATAgg cATATGCAAtagg cataTGCAATAgg cataTGCAATAgg |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N |
-0.006 0.021 0.011 0.017 -0.003 No Change 0.021 0.028 |
| A |
hsa-miR-138-2-3p hsa-miR-205-3p hsa-miR-5007-3p |
8 5 3 |
catatGAAATAGg cataTGAAATAgg CATATGAAatagg |
Created Created Created |
N N N |
-0.015 0.105 -0.006 |
|||
| 101226226 | rs71760784 | - | - |
hsa-miR-190a-3p hsa-miR-5011-5p hsa-miR-6083 |
0 |
tatATATATAAagtttaga taTATATATAaagtttaga tatatATATAAAgtttaga |
Unknown Unknown Unknown |
N N N |
0.005 0.096 0.06 |
| TATA |
hsa-miR-1277-5p hsa-miR-369-3p hsa-miR-374a-5p hsa-miR-374b-5p hsa-miR-5692b hsa-miR-5692c |
0 |
tatATATATTAtaaaagtttaga tatataTATTATAaaagtttaga tatataTATTATAAaagtttaga tatataTATTATAAaagtttaga tatatATATTATAaaagtttaga tatatATATTATAaaagtttaga |
Unknown Unknown Unknown Unknown Unknown Unknown |
N N N N N N |
-0.112 0.025 -0.05 -0.029 -0.047 -0.047 |