SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_000575
Gene Symbol: IL1A
Description: Homo sapiens interleukin 1, alpha (IL1A), mRNA.
Gene Location: chr2(-):113531491-113542971
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr2:g.112774081C>A COSN15427261 AOCS-139-19-0 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-218-2-3p tttgacAACCATGagacca
0 CAUGGUUC m7a Disrupted NA NA 0.040000
hsa-miR-323b-5p tttGACAACCatgagacca
2
AGGUUGUC m7b (m7b->m6c) -0.520000 no TS 11.260000
hsa-miR-4289 tttgacaACAATGagacca
0 GCAUUGUG m6b Created no TS -0.054000 No effect
hsa-miR-218-2-3p tttgacAACCATGagacca
0 CAUGGUUC m7a Disrupted NA NA 0.040000
hsa-miR-323b-5p tttGACAACCatgagacca
2
AGGUUGUC m7b (m7b->m6c) -0.520000 no TS 11.260000
hsa-miR-4289 tttgacaACAATGagacca
0 GCAUUGUG m6b Created no TS -0.054000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.112774103A>G COSN9072658 AOCS-120-3-6 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-452-3p gctaaaattAGATGAactc
2
CUCAUCUG m6b Disrupted -0.079000 0.004000 0.040000
hsa-miR-4735-5p gctaAAATTAGatgaactc
2
CCUAAUUU m7b Disrupted -0.115000 no TS 1.040000
hsa-miR-4775 gctAAAATTAgatgaactc
2
UUAAUUUU m7b (m7b->m6c) 0.157000 0.117000 1.280000
hsa-miR-590-3p gcTAAAATTAgatgaactc
2
UAAUUUUA m8a (m8a->m7b) 0.089000 0.109000 0.090000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.112774433A>T COSN1778408 RK051_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-340-5p gtaTTTATAAatatattta
0 UUAUAAAG m7a (m7a->m6b) 0.029000 no TS 0.020000
hsa-miR-410 gtatTTATATatatattta
6
AAUAUAAC m6b Created 0.004000 0.001000 No effect
hsa-miR-5011-5p gtatttaTATATATAttta
0 UAUAUAUA m8a Created -0.080000 -0.436000 2.440000
hsa-miR-340-5p gtaTTTATAAatatattta
0 UUAUAAAG m7a (m7a->m6b) 0.029 no TS 0.02
hsa-miR-410 gtatTTATATatatattta
0 AAUAUAAC m6b Created 0.004 0.001 No effect
hsa-miR-5011-5p gtatttaTATATATAttta
0 UAUAUAUA m8a Created -0.08 -0.436 2.44

Mutation Mutation ID Sample Name Cancer Type
chr2:g.112774474G>A COSN9072659 AOCS-111-1-X [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2113 gcaaaGCACAAAatgttat
0 AUUUGUGC m7b Created no TS -0.243000 -0.590000
hsa-miR-218-5p gcaAAGCACAAaatgttat
0 UUGUGCUU m8a Created no TS -0.246000 -0.450000
hsa-miR-517a-3p gcaaaGCACGAaatgttat
2
AUCGUGCA m6b Disrupted -0.247000 no TS 0.570000
hsa-miR-517b-3p gcaaaGCACGAaatgttat
2
AUCGUGCA m6b Disrupted -0.247000 no TS 0.570000
hsa-miR-517c-3p gcaaaGCACGAaatgttat
2
AUCGUGCA m6b Disrupted -0.243000 no TS 0.050000
hsa-miR-636 gcaAAGCACAaaatgttat
0 UGUGCUUG m7a (m6b->m7a) no TS -0.087000 0.240000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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