SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_016260
Gene Symbol: IKZF2
Description: Homo sapiens IKAROS family zinc finger 2 (Helios) (IKZF2), transcript variant 2, mRNA.
Gene Location: chr2(-):213864410-214015058
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr2:g.212999961G>A COSN6936995 8062308 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-181a-5p tgtgtaTGAATGTTgtata
 0 AACAUUCA m8a Created no TS -0.115000 0.030000
hsa-miR-181b-5p tgtgtaTGAATGTTgtata
 0 AACAUUCA m8a Created no TS -0.096000 No effect
hsa-miR-181c-5p tgtgtaTGAATGTTgtata
 0 AACAUUCA m8a Created no TS -0.115000 No effect
hsa-miR-181d tgtgtaTGAATGTTgtata
 0 AACAUUCA m8a Created no TS -0.096000 No effect
hsa-miR-4262 tgtgtaTGAATGTtgtata
 0 GACAUUCA m7b Created no TS -0.133000 No effect
hsa-miR-543 tgtgtatGAATGTTgtata
 0 AAACAUUC m7b Created no TS -0.118000 0.020000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.213000252A>T COSN6936996 8012341 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5011-5p atatatataTATATATAtg
 0 UAUAUAUA m8a (m7a->m8a) -0.269000 -0.629000 No effect


Mutation Mutation ID Sample Name Cancer Type
chr2:g.213001359A>G COSN9308016 AOCS-166-1-2 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr2:g.213002896T>C COSN1823331 RK025_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr2:g.213002906A>G COSN5496585 RK155_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4719 tgaattataATTTGTGttt
 0 UCACAAAU m7b (m7b->m6b) 0.178000 0.225000 -1.250000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.213003337T>C COSN6167939 RK136_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4328 gaggtgAAACTGaagtttg
 8
 CCAGUUUU m6b Created 0.306000 0.409000 -0.030000
hsa-miR-5096 gaGGTGAAACtgaagtttg
 2
 GUUUCACC m8a (m7b->m8a) 0.033000 0.060000 No effect


Mutation Mutation ID Sample Name Cancer Type
chr2:g.213004609A>G COSN8279031 PCSI_0083_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr2:g.213004842A>G COSN15347624 0008_CRUK_PC_0008_T2_DNA [prostate][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4639-3p gtagttGAGAGTGcatttg
 6
 UCACUCUC m7b Disrupted -0.169000 -0.116000 0.010000
hsa-miR-501-3p gtagttgagGGTGCATTtg
 0 AAUGCACC m8a (m7a->m8a) no TS -0.056000 -0.260000
hsa-miR-502-3p gtagttgagGGTGCATTtg
 0 AAUGCACC m8a (m7a->m8a) no TS -0.056000 -0.090000
hsa-miR-4639-3p gtagttGAGAGTGcatttg
 6
 UCACUCUC m7b Disrupted -0.169000 -0.116000 0.010000
hsa-miR-501-3p gtagttgagGGTGCATTtg
 0 AAUGCACC m8a (m7a->m8a) no TS -0.056000 -0.260000
hsa-miR-502-3p gtagttgagGGTGCATTtg
 0 AAUGCACC m8a (m7a->m8a) no TS -0.056000 -0.090000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.213005305G>C COSN6167940 RK186_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3675-3p caaaacAGAGATatataga
 1
 CAUCUCUA m6b Disrupted 0.007000 -0.024000 No effect
hsa-miR-654-3p caaaaCAGACATAtataga
 1
 UAUGUCUG m8a Created 0.011000 -0.044000 -0.010000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.213005513G>A COSN6167941 RK308_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3170 gcaagtttgACCCCAatac
 0 CUGGGGUU m6b Created no TS -0.051000 No effect
hsa-miR-3926 gcaagTTTGGCCccaatac
 0 UGGCCAAA m7b Disrupted -0.181000 -0.221000 0.010000
hsa-miR-4260 gcaagtttgGCCCCAAtac
 0 CUUGGGGC m7b (m7b->m6b) -0.080000 -0.058000 0.020000
hsa-miR-5572 gcaagtttgACCCCAAtac
 0 GUUGGGGU m7b (m6b->m7b) -0.061000 -0.075000 -0.160000
hsa-miR-615-5p gcaagtttGACCCCaatac
 12
 GGGGGUCC m6b Created -0.315000 -0.417000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.213005657C>A COSN9873408 C0020T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-224-3p tctgataACCATTTgtgaa
 2
 AAAAUGGU m7b Disrupted 0.094000 0.045000 0.100000
hsa-miR-522-3p tctgataACCATTTgtgaa
 2
 AAAAUGGU m7b Disrupted 0.085000 0.036000 0.050000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.213005925A>G COSN1823333 RK141_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-33a-3p ttccaAAACATTtaattgt
 0 CAAUGUUU m7b Disrupted 0.575000 0.491000 No effect
hsa-miR-4307 ttccAAAACATTtaattgt
 3
 AAUGUUUU m8a Disrupted 0.676000 0.508000 No effect
hsa-miR-33a-3p ttccaAAACATTtaattgt
 0 CAAUGUUU m7b Disrupted 0.575 0.491 -0.14
hsa-miR-4307 ttccAAAACATTtaattgt
 0 AAUGUUUU m8a Disrupted 0.676 0.508 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.213006735C>T COSN6556712 ICGC_MB88 [central_nervous_system][brain][primitive_neuroectodermal_tumour-medulloblastoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-20b-3p tttaaACTACAGgtagtta
 15
 ACUGUAGU m7b Disrupted -0.137000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.213006968G>T COSN191203 PD3890a [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3973 tctgggtagTACTTTGgtg
 0 ACAAAGUA m7b (m6b->m7b) -0.064000 -0.091000 No effect
hsa-miR-548av-5p tctgggtaGTACTTTggtg
 2
 AAAAGUAC m7b Created 0.218000 0.152000 No effect
hsa-miR-548k tctgggtaGTACTTTggtg
 2
 AAAAGUAC m7b Created 0.218000 0.152000 No effect
hsa-miR-3973 tctgggtagTACTTTGgtg
 0 ACAAAGUA m7b (m6b->m7b) -0.064 -0.091 No effect
hsa-miR-548av-5p tctgggtaGTACTTTggtg
 0 AAAAGUAC m7b Created 0.218 0.152 No effect
hsa-miR-548k tctgggtaGTACTTTggtg
 0 AAAAGUAC m7b Created 0.218 0.152 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.213007258A>G COSN8608557 88_T [prostate][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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