SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001220774
Gene Symbol: IKZF1
Description: Homo sapiens IKAROS family zinc finger 1 (Ikaros) (IKZF1), transcript variant 2, mRNA.
Gene Location: chr7(+):50344377-50472798
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr7:g.50400883C>T COSN9992105 AOCS-147-1-1 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4274 tccccaGACTGCTGgctga
 2
 CAGCAGUC m8a Created -0.092000 -0.213000 No effect
hsa-miR-4530 tccccagaCTGCTGGctga
 3
 CCCAGCAG m7b Created -0.089000 -0.288000 -2.070000
hsa-miR-622 tcccCAGACTGctggctga
 0 ACAGUCUG m7b Created -0.031000 -0.101000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr7:g.50400934C>T COSN8026085 8057484 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-382-3p ttctccaAATGATTagtct
 0 AAUCAUUC m7a Created NA NA -0.010000
hsa-miR-5707 ttctcCAAACGattagtct
 0 ACGUUUGA m6b Disrupted -0.235000 -0.083000 0.010000
hsa-miR-579 ttctcCAAATGAttagtct
 1
 UUCAUUUG m7b Created 0.519000 0.474000 -1.650000
hsa-miR-644b-3p ttctcCAAATGAttagtct
 1
 UUCAUUUG m7b Created 0.467000 0.422000 No effect


Mutation Mutation ID Sample Name Cancer Type
chr7:g.50401034G>A COSN8802326 SS6003317 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr7:g.50401299C>T COSN9992106 AOCS-112-1-2 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr7:g.50401399A>G COSN6884820 RK205_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4279 tagGAGGAGActgtcttcc
 2
 CUCUCCUC m7b (m7b->m6b) 0.103000 0.100000 0.010000
hsa-miR-5193 tagGAGGAGGctgtcttcc
 2
 UCCUCCUC m7b (m6b->m7b) -0.055000 -0.074000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr7:g.50401551C>A COSN15182291 LP6005334-DNA_C02 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1 gcaACATTCCtcagaaacc
 2
 UGGAAUGU m7b (m7b->m6b) -0.051000 no TS 3.080000
hsa-miR-206 gcaACATTCCtcagaaacc
 2
 UGGAAUGU m7b (m7b->m6b) -0.051000 no TS 0.020000
hsa-miR-3915 gcaacaTTCCTCAgaaacc
 1
 UUGAGGAA m7b Disrupted -0.277000 -0.206000 -0.060000
hsa-miR-3928 gcaacaTTCCTCagaaacc
 2
 GGAGGAAC m6b Disrupted -0.021000 -0.006000 0.260000
hsa-miR-4303 gcaacattcCTCAGAAacc
 8
 UUCUGAGC m7a (m7a->m6b) -0.069000 -0.034000 0.540000
hsa-miR-4502 gcaacatTCATCAGaaacc
 0 GCUGAUGA m7b Created -0.029000 -0.198000 -3.230000
hsa-miR-4649-3p gcaacattCCTCAGAaacc
 1
 UCUGAGGC m7a Disrupted -0.185000 -0.126000 0.080000
hsa-miR-4762-3p gcaacattcATCAGAAacc
 0 CUUCUGAU m7b (m6c->m7b) 0.090000 0.064000 -1.540000
hsa-miR-613 gcaACATTCCTcagaaacc
 2
 AGGAAUGU m8a Disrupted -0.070000 no TS 0.020000

Mutation Mutation ID Sample Name Cancer Type
chr7:g.50401813C>A COSN9992107 AOCS-091-3-0 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1285-3p gaaGCCCAGAatctctgtt
 0 UCUGGGCA m7a (m6a->m7a) -0.064000 -0.142000 -0.010000
hsa-miR-4314 gaagCCCAGAatctctgtt
 3
 CUCUGGGA m6b Created -0.091000 -0.146000 No effect
hsa-miR-4486 gaaGCCCAGCatctctgtt
 0 GCUGGGCG m7a (m7a->m6a) no TS -0.099000 No effect
hsa-miR-4708-5p gaagcccaGCATCTCTgtt
 5
 AGAGAUGC m8a Disrupted -0.055000 no TS 4.040000
hsa-miR-5189 gaaGCCCAGAatctctgtt
 0 UCUGGGCA m7a (m6a->m7a) -0.064000 -0.142000 No effect
hsa-miR-5589-5p gaagCCCAGCatctctgtt
 1
 GGCUGGGU m6b Disrupted -0.176000 -0.101000 No effect
hsa-miR-612 gaaGCCCAGCatctctgtt
 0 GCUGGGCA m7a (m7a->m6a) -0.064000 -0.145000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr7:g.50402494C>G COSN4934126 PD4115a [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4433-3p gaaatcACTCCTGggggag
 2
 ACAGGAGU m7b Disrupted 0.106000 no TS 0.070000
hsa-miR-4519 gaaatCACTGCTGggggag
 2
 CAGCAGUG m8a Created -0.081000 -0.048000 -0.010000
hsa-miR-4530 gaaatcaCTGCTGGGggag
 3
 CCCAGCAG m8a Created -0.089000 -0.058000 -0.010000
hsa-miR-4765 gaaATCACTCctgggggag
 3
 UGAGUGAU m7b (m7b->m6b) 0.053000 no TS No effect
hsa-miR-665 gaaatcaCTCCTGGgggag
 0 ACCAGGAG m7b Disrupted -0.429000 -0.449000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr7:g.50403081T>A COSN8026086 8014964 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-186-5p tgcaggaATTCTTTtctaa
 5
 CAAAGAAU m7b Disrupted 0.272000 0.134000 0.040000
hsa-miR-548l tgcaggaATACTTTTctaa
 13
 AAAAGUAU m8a Created 0.070000 0.209000 -0.160000
hsa-miR-548n tgcaggaaTACTTTTctaa
 0 CAAAAGUA m7b Created no TS 0.140000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr7:g.50403424C>T COSN9944362 C0038T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3529-3p atgcactcTTGTTGTgttt
 0 AACAACAA m7b Created 0.171000 0.298000 No effect
hsa-miR-4693-3p atgCACTCTCgttgtgttt
 3
 UGAGAGUG m7b (m7b->m6b) 0.021000 0.005000 No effect
hsa-miR-5003-5p atgcactctTGTTGTGttt
 8
 UCACAACA m7b (m6c->m7b) -0.356000 -0.388000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr7:g.50403844A>G COSN8303297 PCSI_0083_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-128 tttgactgCACTGTGAgtt
 17
 UCACAGUG m8a Disrupted -0.146000 -0.111000 No effect
hsa-miR-143-5p tttgACTGCACtgtgagtt
 2
 GGUGCAGU m7b Disrupted -0.047000 no TS No effect
hsa-miR-148a-3p tttgacTGCACTGtgagtt
 2
 UCAGUGCA m7b Disrupted -0.060000 -0.003000 No effect
hsa-miR-148b-3p tttgacTGCACTGtgagtt
 2
 UCAGUGCA m7b Disrupted -0.060000 -0.003000 No effect
hsa-miR-152 tttgacTGCACTGtgagtt
 2
 UCAGUGCA m7b Disrupted -0.060000 -0.003000 No effect
hsa-miR-27a-3p tttgactgcACTGTGAgtt
 0 UUCACAGU m7b (m7b->m6c) -0.071000 -0.082000 No effect
hsa-miR-27b-3p tttgactgcACTGTGAgtt
 0 UUCACAGU m7b (m7b->m6c) -0.071000 -0.082000 No effect
hsa-miR-3681-3p tttgactgCACTGTGagtt
 17
 ACACAGUG m7b Disrupted -0.167000 -0.143000 No effect


Mutation Mutation ID Sample Name Cancer Type
chr7:g.50404198G>T COSN8516717 3584_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr7:g.50404249G>T COSN8516718 J90_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr7:g.50404470G>A COSN5226138 SS6003323 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-122-3p cacacTGGCGTaagagaag
 0 AACGCCAU m6b Disrupted -0.262000 -0.086000 0.830000
hsa-miR-4633-5p cacactGGCATAagagaag
 0 AUAUGCCU m6b Created no TS -0.060000 No effect
hsa-miR-491-3p cacactgGCATAAGagaag
 0 CUUAUGCA m7a Created NA NA -0.080000
hsa-miR-122-3p cacacTGGCGTaagagaag
 0 AACGCCAU m6b Disrupted -0.262000 -0.086000 0.830000
hsa-miR-4633-5p cacactGGCATAagagaag
 0 AUAUGCCU m6b Created no TS -0.060000 No effect
hsa-miR-491-3p cacactgGCATAAGagaag
 0 CUUAUGCA m7a Created NA NA -0.080000
hsa-miR-122-3p cacacTGGCGTaagagaag
 0 AACGCCAU m6b Disrupted -0.262000 -0.086000 0.830000
hsa-miR-4633-5p cacactGGCATAagagaag
 0 AUAUGCCU m6b Created no TS -0.060000 No effect
hsa-miR-491-3p cacactgGCATAAGagaag
 0 CUUAUGCA m7a Created NA NA -0.080000

Mutation Mutation ID Sample Name Cancer Type
chr7:g.50404594T>C COSN8802327 SS6003149 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1197 tgtgGTGTCCTgatgtggc
 2
 UAGGACAC m7b Created -0.089000 -0.178000 No effect
hsa-miR-4436a tgtggTGTCCTGatgtggc
 0 GCAGGACA m7b Created no TS -0.192000 No effect
hsa-miR-5000-3p tgtggTGTCCTGAtgtggc
 0 UCAGGACA m8a Created no TS -0.192000 -0.010000

Mutation Mutation ID Sample Name Cancer Type
chr7:g.50404837C>T COSN8303298 ASHPC_0009_Pa_P [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3120-3p gccttttgaTGCTGTaaat
 2
 CACAGCAA m6b Created -0.140000 -0.263000 -0.030000

Mutation Mutation ID Sample Name Cancer Type
chr7:g.50404961A>T COSN9992108 AOCS-138-3-X [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-let-7a-3p ttggatgtTTGTATAGaat
 0 CUAUACAA m8a Created no TS -0.102000 -0.810000
hsa-let-7b-3p ttggatgtTTGTATAGaat
 0 CUAUACAA m8a Created no TS -0.102000 -2.090000
hsa-let-7f-1-3p ttggatgtTTGTATAGaat
 0 CUAUACAA m8a Created no TS -0.111000 -3.700000
hsa-let-7f-2-3p ttggatgttTGTATAGaat
 0 CUAUACAG m7a (m6b->m7a) NA NA -1.100000
hsa-miR-1284 ttggatgttTGTATAGAat
 0 UCUAUACA m8a (m7b->m8a) -0.126000 -0.347000 -3.710000
hsa-miR-4666a-3p ttggatgtTTGTATagaat
 12
 CAUACAAU m6b Created 0.054000 0.023000 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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