SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_001220769 |
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Gene Symbol: | IKZF1 |
Description: | Homo sapiens IKAROS family zinc finger 1 (Ikaros) (IKZF1), transcript variant 2, mRNA. |
Gene Location: | chr7(+):50344377-50472798 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50400883C>T | COSN9992105 | AOCS-147-1-1 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4274 |
tccccaGACTGCTGgctga |
2 |
CAGCAGUC | m8a | Created | -0.092000 | -0.213000 | No effect |
hsa-miR-4530 |
tccccagaCTGCTGGctga |
3 |
CCCAGCAG | m7b | Created | -0.089000 | -0.288000 |
-2.070000 |
hsa-miR-622 |
tcccCAGACTGctggctga |
0 | ACAGUCUG | m7b | Created | -0.031000 | -0.101000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50400934C>T | COSN8026085 | 8057484 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-382-3p |
ttctccaAATGATTagtct |
0 | AAUCAUUC | m7a | Created | NA | NA |
-0.010000 |
hsa-miR-5707 |
ttctcCAAACGattagtct |
0 | ACGUUUGA | m6b | Disrupted | -0.235000 | -0.083000 |
0.010000 |
hsa-miR-579 |
ttctcCAAATGAttagtct |
1 |
UUCAUUUG | m7b | Created | 0.519000 | 0.474000 |
-1.650000 |
hsa-miR-644b-3p |
ttctcCAAATGAttagtct |
1 |
UUCAUUUG | m7b | Created | 0.467000 | 0.422000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50401034G>A | COSN8802326 | SS6003317 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50401299C>T | COSN9992106 | AOCS-112-1-2 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50401399A>G | COSN6884820 | RK205_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4279 |
tagGAGGAGActgtcttcc |
2 |
CUCUCCUC | m7b | (m7b->m6b) | 0.103000 | 0.100000 |
0.010000 |
hsa-miR-5193 |
tagGAGGAGGctgtcttcc |
2 |
UCCUCCUC | m7b | (m6b->m7b) | -0.055000 | -0.074000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50401551C>A | COSN15182291 | LP6005334-DNA_C02 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1 |
gcaACATTCCtcagaaacc |
2 |
UGGAAUGU | m7b | (m7b->m6b) | -0.051000 | no TS |
3.080000 |
hsa-miR-206 |
gcaACATTCCtcagaaacc |
2 |
UGGAAUGU | m7b | (m7b->m6b) | -0.051000 | no TS |
0.020000 |
hsa-miR-3915 |
gcaacaTTCCTCAgaaacc |
1 |
UUGAGGAA | m7b | Disrupted | -0.277000 | -0.206000 |
-0.060000 |
hsa-miR-3928 |
gcaacaTTCCTCagaaacc |
2 |
GGAGGAAC | m6b | Disrupted | -0.021000 | -0.006000 |
0.260000 |
hsa-miR-4303 |
gcaacattcCTCAGAAacc |
8 |
UUCUGAGC | m7a | (m7a->m6b) | -0.069000 | -0.034000 |
0.540000 |
hsa-miR-4502 |
gcaacatTCATCAGaaacc |
0 | GCUGAUGA | m7b | Created | -0.029000 | -0.198000 |
-3.230000 |
hsa-miR-4649-3p |
gcaacattCCTCAGAaacc |
1 |
UCUGAGGC | m7a | Disrupted | -0.185000 | -0.126000 |
0.080000 |
hsa-miR-4762-3p |
gcaacattcATCAGAAacc |
0 | CUUCUGAU | m7b | (m6c->m7b) | 0.090000 | 0.064000 |
-1.540000 |
hsa-miR-613 |
gcaACATTCCTcagaaacc |
2 |
AGGAAUGU | m8a | Disrupted | -0.070000 | no TS |
0.020000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50401813C>A | COSN9992107 | AOCS-091-3-0 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1285-3p |
gaaGCCCAGAatctctgtt |
0 | UCUGGGCA | m7a | (m6a->m7a) | -0.064000 | -0.142000 |
-0.010000 |
hsa-miR-4314 |
gaagCCCAGAatctctgtt |
3 |
CUCUGGGA | m6b | Created | -0.091000 | -0.146000 | No effect |
hsa-miR-4486 |
gaaGCCCAGCatctctgtt |
0 | GCUGGGCG | m7a | (m7a->m6a) | no TS | -0.099000 | No effect |
hsa-miR-4708-5p |
gaagcccaGCATCTCTgtt |
5 |
AGAGAUGC | m8a | Disrupted | -0.055000 | no TS |
4.040000 |
hsa-miR-5189 |
gaaGCCCAGAatctctgtt |
0 | UCUGGGCA | m7a | (m6a->m7a) | -0.064000 | -0.142000 | No effect |
hsa-miR-5589-5p |
gaagCCCAGCatctctgtt |
1 |
GGCUGGGU | m6b | Disrupted | -0.176000 | -0.101000 | No effect |
hsa-miR-612 |
gaaGCCCAGCatctctgtt |
0 | GCUGGGCA | m7a | (m7a->m6a) | -0.064000 | -0.145000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50402494C>G | COSN4934126 | PD4115a | [breast][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4433-3p |
gaaatcACTCCTGggggag |
2 |
ACAGGAGU | m7b | Disrupted | 0.106000 | no TS |
0.070000 |
hsa-miR-4519 |
gaaatCACTGCTGggggag |
2 |
CAGCAGUG | m8a | Created | -0.081000 | -0.048000 |
-0.010000 |
hsa-miR-4530 |
gaaatcaCTGCTGGGggag |
3 |
CCCAGCAG | m8a | Created | -0.089000 | -0.058000 |
-0.010000 |
hsa-miR-4765 |
gaaATCACTCctgggggag |
3 |
UGAGUGAU | m7b | (m7b->m6b) | 0.053000 | no TS | No effect |
hsa-miR-665 |
gaaatcaCTCCTGGgggag |
0 | ACCAGGAG | m7b | Disrupted | -0.429000 | -0.449000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50403081T>A | COSN8026086 | 8014964 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-186-5p |
tgcaggaATTCTTTtctaa |
5 |
CAAAGAAU | m7b | Disrupted | 0.272000 | 0.134000 |
0.040000 |
hsa-miR-548l |
tgcaggaATACTTTTctaa |
13 |
AAAAGUAU | m8a | Created | 0.070000 | 0.209000 |
-0.160000 |
hsa-miR-548n |
tgcaggaaTACTTTTctaa |
0 | CAAAAGUA | m7b | Created | no TS | 0.140000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50403424C>T | COSN9944362 | C0038T | [kidney][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3529-3p |
atgcactcTTGTTGTgttt |
0 | AACAACAA | m7b | Created | 0.171000 | 0.298000 | No effect |
hsa-miR-4693-3p |
atgCACTCTCgttgtgttt |
3 |
UGAGAGUG | m7b | (m7b->m6b) | 0.021000 | 0.005000 | No effect |
hsa-miR-5003-5p |
atgcactctTGTTGTGttt |
8 |
UCACAACA | m7b | (m6c->m7b) | -0.356000 | -0.388000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50403844A>G | COSN8303297 | PCSI_0083_Pa_P_526 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-128 |
tttgactgCACTGTGAgtt |
17 |
UCACAGUG | m8a | Disrupted | -0.146000 | -0.111000 | No effect |
hsa-miR-143-5p |
tttgACTGCACtgtgagtt |
2 |
GGUGCAGU | m7b | Disrupted | -0.047000 | no TS | No effect |
hsa-miR-148a-3p |
tttgacTGCACTGtgagtt |
2 |
UCAGUGCA | m7b | Disrupted | -0.060000 | -0.003000 | No effect |
hsa-miR-148b-3p |
tttgacTGCACTGtgagtt |
2 |
UCAGUGCA | m7b | Disrupted | -0.060000 | -0.003000 | No effect |
hsa-miR-152 |
tttgacTGCACTGtgagtt |
2 |
UCAGUGCA | m7b | Disrupted | -0.060000 | -0.003000 | No effect |
hsa-miR-27a-3p |
tttgactgcACTGTGAgtt |
0 | UUCACAGU | m7b | (m7b->m6c) | -0.071000 | -0.082000 | No effect |
hsa-miR-27b-3p |
tttgactgcACTGTGAgtt |
0 | UUCACAGU | m7b | (m7b->m6c) | -0.071000 | -0.082000 | No effect |
hsa-miR-3681-3p |
tttgactgCACTGTGagtt |
17 |
ACACAGUG | m7b | Disrupted | -0.167000 | -0.143000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50404198G>T | COSN8516717 | 3584_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50404249G>T | COSN8516718 | J90_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50404470G>A | COSN5226138 | SS6003323 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-122-3p |
cacacTGGCGTaagagaag |
0 | AACGCCAU | m6b | Disrupted | -0.262000 | -0.086000 |
0.830000 |
hsa-miR-4633-5p |
cacactGGCATAagagaag |
0 | AUAUGCCU | m6b | Created | no TS | -0.060000 | No effect |
hsa-miR-491-3p |
cacactgGCATAAGagaag |
0 | CUUAUGCA | m7a | Created | NA | NA |
-0.080000 |
hsa-miR-122-3p |
cacacTGGCGTaagagaag |
0 | AACGCCAU | m6b | Disrupted | -0.262000 | -0.086000 |
0.830000 |
hsa-miR-4633-5p |
cacactGGCATAagagaag |
0 | AUAUGCCU | m6b | Created | no TS | -0.060000 | No effect |
hsa-miR-491-3p |
cacactgGCATAAGagaag |
0 | CUUAUGCA | m7a | Created | NA | NA |
-0.080000 |
hsa-miR-122-3p |
cacacTGGCGTaagagaag |
0 | AACGCCAU | m6b | Disrupted | -0.262000 | -0.086000 |
0.830000 |
hsa-miR-4633-5p |
cacactGGCATAagagaag |
0 | AUAUGCCU | m6b | Created | no TS | -0.060000 | No effect |
hsa-miR-491-3p |
cacactgGCATAAGagaag |
0 | CUUAUGCA | m7a | Created | NA | NA |
-0.080000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50404594T>C | COSN8802327 | SS6003149 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1197 |
tgtgGTGTCCTgatgtggc |
2 |
UAGGACAC | m7b | Created | -0.089000 | -0.178000 | No effect |
hsa-miR-4436a |
tgtggTGTCCTGatgtggc |
0 | GCAGGACA | m7b | Created | no TS | -0.192000 | No effect |
hsa-miR-5000-3p |
tgtggTGTCCTGAtgtggc |
0 | UCAGGACA | m8a | Created | no TS | -0.192000 |
-0.010000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50404837C>T | COSN8303298 | ASHPC_0009_Pa_P | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3120-3p |
gccttttgaTGCTGTaaat |
2 |
CACAGCAA | m6b | Created | -0.140000 | -0.263000 |
-0.030000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr7:g.50404961A>T | COSN9992108 | AOCS-138-3-X | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-let-7a-3p |
ttggatgtTTGTATAGaat |
0 | CUAUACAA | m8a | Created | no TS | -0.102000 |
-0.810000 |
hsa-let-7b-3p |
ttggatgtTTGTATAGaat |
0 | CUAUACAA | m8a | Created | no TS | -0.102000 |
-2.090000 |
hsa-let-7f-1-3p |
ttggatgtTTGTATAGaat |
0 | CUAUACAA | m8a | Created | no TS | -0.111000 |
-3.700000 |
hsa-let-7f-2-3p |
ttggatgttTGTATAGaat |
0 | CUAUACAG | m7a | (m6b->m7a) | NA | NA |
-1.100000 |
hsa-miR-1284 |
ttggatgttTGTATAGAat |
0 | UCUAUACA | m8a | (m7b->m8a) | -0.126000 | -0.347000 |
-3.710000 |
hsa-miR-4666a-3p |
ttggatgtTTGTATagaat |
12 |
CAUACAAU | m6b | Created | 0.054000 | 0.023000 | No effect |