SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
  Home Search Help Download  

PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001007139
Gene Symbol: IGF2
Description: Homo sapiens insulin-like growth factor 2 (somatomedin A) (IGF2), transcript variant 1, mRNA.
Gene Location: chr11(-):2150346-2170833
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr11:g.2129357C>T COSN8641374 522_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-602 tgtctcctcCCCGTGTCcc
 4
 GACACGGG m8a (m8a->m7a) -0.407000 -0.228000 2.580000
hsa-miR-765 tgtCTCCTCCccgtgtccc
 4
 UGGAGGAG m7b (m7b->m6c) -0.310000 -0.147000 0.250000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2129540G>A COSN14497060 8069334 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-378a-5p tgcccattcGTCAGGAcac
 1
 CUCCUGAC m7b (m7b->m6b) -0.080000 0.013000 0.010000
hsa-miR-4502 tgcccatTCATCAGgacac
 0 GCUGAUGA m7b Created no TS -0.105000 -1.640000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2129630A>G COSN6998049 8034278 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1587 ttggacagaAGCCCAAaga
 2
 UUGGGCUG m7a (m7a->m6a) -0.115000 no TS No effect
hsa-miR-27a-5p ttggacagAAGCCCaaaga
 2
 AGGGCUUA m6b Disrupted -0.139000 no TS No effect
hsa-miR-2861 ttggacagAGGCCCaaaga
 0 GGGGCCUG m6b Created no TS -0.161000 No effect
hsa-miR-3182 ttggACAGAAGCccaaaga
 0 GCUUCUGU m8a Disrupted -0.003000 no TS No effect
hsa-miR-4674 ttggacagaAGCCCAaaga
 2
 CUGGGCUC m6b Disrupted -0.213000 -0.106000 No effect
hsa-miR-4757-5p ttggacAGAGGCCcaaaga
 9
 AGGCCUCU m7b Created -0.144000 -0.293000 -0.950000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2129665G>A COSN8641375 545_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-636 tcggCAAGCACcctgtgag
 1
 UGUGCUUG m7b Created 0.038000 0.028000 -1.950000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2129866C>T COSN8217716 PCSI_0083_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3648 ccaccaCCGCGGCgcctag
 1
 AGCCGCGG m7b Disrupted -0.227000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2129968G>A COSN8438761 AOCS-160-1-6 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4330 gtcaggcggATCTGAGccc
 0 CCUCAGAU m7b (m6b->m7b) no TS 0.064000 -1.140000
hsa-miR-5100 gtcaggcgGATCTGAgccc
 0 UUCAGAUC m7b Created no TS 0.089000 -1.280000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2130417C>T COSN8438765 AOCS-113-1-5 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-211-3p ttcatctGTCCCTGttgct
 2
 GCAGGGAC m7b Disrupted -0.417000 -0.323000 1.680000
hsa-miR-873-5p ttcatctGTTCCTGttgct
 0 GCAGGAAC m7b Created no TS -0.040000 -5.170000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2130441G>C COSN8438766 AOCS-166-1-2 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1226-5p tatcGCCCTCAttggattt
 0 GUGAGGGC m7b Created no TS -0.105000 No effect
hsa-miR-3127-5p tatcGCCCTGATtggattt
 2
 AUCAGGGC m8a Disrupted -0.186000 -0.082000 3.110000
hsa-miR-3141 tatCGCCCTCattggattt
 0 GAGGGCGG m7a (m6b->m7a) NA NA 0.010000
hsa-miR-3616-3p tatcGCCCTCattggattt
 0 CGAGGGCA m6b Created no TS -0.091000 No effect
hsa-miR-3918 tatcGCCCTGattggattt
 2
 ACAGGGCC m6b Disrupted -0.081000 -0.001000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2130494C>T COSN5259185 HX34T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-517a-3p gcaagaacGCACGAagcca
 4
 AUCGUGCA m6b Disrupted -0.090000 no TS No effect
hsa-miR-517b-3p gcaagaacGCACGAagcca
 4
 AUCGUGCA m6b Disrupted -0.090000 no TS No effect
hsa-miR-517c-3p gcaagaacGCACGAagcca
 4
 AUCGUGCA m6b Disrupted -0.090000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2130577A>T COSN6608581 CHC205T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1914-3p tttttttttACCCCTCCtt
 2
 GGAGGGGU m8a (m8a->m7a) -0.179000 -0.047000 No effect
hsa-miR-3148 tttttTTTTTCCcctcctt
 5
 UGGAAAAA m7b Created 0.164000 0.291000 -3.330000
hsa-miR-4668-5p ttttttTTTTCCCctcctt
 0 AGGGAAAA m7b Created no TS -0.031000 -4.460000
hsa-miR-5194 tttttttttACCCCTCctt
 2
 UGAGGGGU m7b (m7b->m6b) -0.201000 -0.051000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2130588G>T COSN6608582 CHC205T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3613-3p tttTTTTTTGTtttttttt
 0 ACAAAAAA m8a Disrupted 0.096000 no TS 0.230000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2130606C>T COSN8641376 187_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3148 ggcaTTTTTCCtttttttt
 5
 UGGAAAAA m7b Disrupted 0.164000 0.062000 2.260000


Mutation Mutation ID Sample Name Cancer Type
chr11:g.2130989G>A COSN6998053 8016470 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr11:g.2131624->CAG cosmic_v64_1870280 NA [upper_aerodigestive_tract][mouth][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1231 cacacagcacaCCAGACAtgcacaca
 0 GUGUCUGG m7b (m6b->m7b) no TS -0.004000 -1.910000
hsa-miR-147a cacacagCACACACatgcacaca
 0 GUGUGUGG m7a Disrupted 0.027000 0.028000 No effect
hsa-miR-3607-5p cacacagcacaCACATGCacaca
 0 GCAUGUGA m7a (m7a->m6a) 0.110000 0.110000 0.170000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2131629->CAT cosmic_v64_1870280 NA [upper_aerodigestive_tract][mouth][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4728-3p cacagcacaCAGCATcacacacatgc
 0 CAUGCUGA m6b Created NA NA -0.370000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2132018G>C COSN8641377 545_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-147a cagCACACACatgagcaca
 2
 GUGUGUGG m7a (m6b->m7a) 0.027000 0.027000 -0.010000
hsa-miR-3607-5p cagcacaCACATGagcaca
 0 GCAUGUGA m6b Created 0.110000 0.139000 -0.200000
hsa-miR-452-3p cagcacaCAGATGAGcaca
 0 CUCAUCUG m8a Disrupted 0.028000 no TS 3.080000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2132075A>G COSN10082969 C0076T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1206 cacgCATGAACAcagcaca
 1
 UGUUCAUG m8a Disrupted 0.126000 0.139000 0.030000
hsa-miR-124-5p cacgcaTGAACACagcaca
 1
 CGUGUUCA m7b Disrupted 0.267000 0.324000 1.370000
hsa-miR-5008-3p cacgcatgAGCACAGcaca
 1
 CCUGUGCU m7b Created -0.155000 -0.166000 -0.120000
hsa-miR-1206 cacgCATGAACAcagcaca
 1
 UGUUCAUG m8a Disrupted 0.126000 0.139000 0.030000
hsa-miR-124-5p cacgcaTGAACACagcaca
 1
 CGUGUUCA m7b Disrupted 0.267000 0.324000 1.370000
hsa-miR-5008-3p cacgcatgAGCACAGcaca
 1
 CCUGUGCU m7b Created -0.155000 -0.166000 -0.120000
hsa-miR-1206 cacgCATGAACAcagcaca
 1
 UGUUCAUG m8a Disrupted 0.126000 0.139000 0.030000
hsa-miR-124-5p cacgcaTGAACACagcaca
 1
 CGUGUUCA m7b Disrupted 0.267000 0.324000 1.370000
hsa-miR-5008-3p cacgcatgAGCACAGcaca
 1
 CCUGUGCU m7b Created -0.155000 -0.166000 -0.120000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2132078T>C COSN10082970 C0076T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1206 gcacacgCATGAACAcagc
 1
 UGUUCAUG m8a Disrupted 0.126000 0.139000 0.040000
hsa-miR-124-5p gcacacgcaTGAACACagc
 1
 CGUGUUCA m7b (m7b->m6b) 0.267000 0.334000 0.820000
hsa-miR-517a-3p gcacacGCACGAacacagc
 4
 AUCGUGCA m6b Created -0.090000 -0.232000 -0.680000
hsa-miR-517b-3p gcacacGCACGAacacagc
 4
 AUCGUGCA m6b Created -0.090000 -0.232000 -0.680000
hsa-miR-517c-3p gcacacGCACGAacacagc
 4
 AUCGUGCA m6b Created -0.090000 -0.232000 -0.910000
hsa-miR-1206 gcacacgCATGAACAcagc
 1
 UGUUCAUG m8a Disrupted 0.126000 0.139000 0.040000
hsa-miR-124-5p gcacacgcaTGAACACagc
 1
 CGUGUUCA m7b (m7b->m6b) 0.267000 0.334000 0.820000
hsa-miR-517a-3p gcacacGCACGAacacagc
 4
 AUCGUGCA m6b Created -0.090000 -0.232000 -0.680000
hsa-miR-517b-3p gcacacGCACGAacacagc
 4
 AUCGUGCA m6b Created -0.090000 -0.232000 -0.680000
hsa-miR-517c-3p gcacacGCACGAacacagc
 4
 AUCGUGCA m6b Created -0.090000 -0.232000 -0.910000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2132081G>A COSN15589267 C0006T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-147a acagCACACACatgaacac
 2
 GUGUGUGG m7a Created 0.027000 0.024000 0.040000
hsa-miR-3607-5p acagcacaCACATGaacac
 0 GCAUGUGA m6b Created 0.110000 0.116000 -0.940000
hsa-miR-147a acagCACACACatgaacac
 2
 GUGUGUGG m7a Created 0.027000 0.024000 0.040000
hsa-miR-3607-5p acagcacaCACATGaacac
 0 GCAUGUGA m6b Created 0.110000 0.116000 -0.940000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Genome Browser