| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_014586 |
|---|---|
| Gene Symbol: | HUNK |
| Description: | Homo sapiens hormonally up-regulated Neu-associated kinase (HUNK), mRNA. |
| Gene Location: | chr21(+):33245627-33376377 |
| Browse Associations | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr21:g.31999195C>T | COSN8868797 | SNUH_G45_S1 | [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-193a-3p |
ttgGGCCAGTggggtttgg |
2 |
AACUGGCC | m7b | (m6b->m7b) | -0.202000 | -0.258000 | No effect | |
| hsa-miR-193b-3p |
ttgGGCCAGTggggtttgg |
2 |
AACUGGCC | m7b | (m6b->m7b) | -0.193000 | -0.249000 | No effect | |
| hsa-miR-4286 |
ttgggccAGTGGGGTttgg |
1 |
ACCCCACU | m8a | Created | -0.279000 | -0.558000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr21:g.31999206G>T | COSN8407881 | B66-Tumor | [urinary_tract][bladder][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1273d |
gggttTGGGTTatctctag |
0 | GAACCCAU | m6b | Created | no TS | -0.147000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr21:g.31999227T>G | COSN15323303 | SNUH_G76_S1 | [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1468 |
aacagcAACGGAacagagc |
0 | CUCCGUUU | m6b | Created | no TS | -0.195000 |
-6.630000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr21:g.31999938A>G | COSN5985378 | RK217_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1470 |
tggatGGAGGGatgagaag |
0 | GCCCUCCG | m6b | Created | no TS | -0.148000 |
-0.950000 |
|
| hsa-miR-188-5p |
tggatggAGGGATGagaag |
0 | CAUCCCUU | m7a | Created | NA | NA | No effect | |
| hsa-miR-3675-3p |
tggatggAGAGATGagaag |
0 | CAUCUCUA | m7a | Disrupted | NA | NA | No effect | |
| hsa-miR-452-3p |
tggatggagAGATGAGaag |
2 |
CUCAUCUG | m7a | (m7a->m6b) | 0.089000 | 0.089000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr21:g.32001038G>A | COSN14489447 | 8068577 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-212-5p |
tgggagGCCAAGGcaggtg |
0 | ACCUUGGC | m7b | Created | 0.004000 | 0.043000 |
-0.080000 |
|
| hsa-miR-4312 |
tgggaggcCAAGGCaggtg |
0 | GGCCUUGU | m6b | Created | no TS | 0.033000 |
-0.010000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr21:g.32002238C>T | COSN1890891 | RK041_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr21:g.32002358A>G | COSN4908328 | CPCG_0183_Pr_P_P3 | [prostate][NS][carcinoma][adenocarcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-216a |
aaagtgcTGAGATTAcagg |
1 |
UAAUCUCA | m8a | Disrupted | 0.215000 | no TS |
0.010000 |
|
| hsa-miR-216b |
aaagtgctGAGATTacagg |
1 |
AAAUCUCU | m6b | Disrupted | 0.132000 | no TS | No effect | |
| hsa-miR-4530 |
aaagTGCTGGGattacagg |
1 |
CCCAGCAG | m7a | Created | -0.070000 | -0.070000 | No effect | |
| hsa-miR-4733-5p |
aaagtgcTGGGATTacagg |
0 | AAUCCCAA | m7a | Created | NA | NA |
-0.210000 |
|
| hsa-miR-216a |
aaagtgcTGAGATTAcagg |
1 |
UAAUCUCA | m8a | Disrupted | 0.215 | no TS |
0.01 |
|
| hsa-miR-216b |
aaagtgctGAGATTacagg |
0 | AAAUCUCU | m6b | Disrupted | 0.132 | no TS | No effect | |
| hsa-miR-4530 |
aaagTGCTGGGattacagg |
0 | CCCAGCAG | m7a | Created | -0.07 | -0.07 | No effect | |
| hsa-miR-4733-5p |
aaagtgcTGGGATTacagg |
0 | AAUCCCAA | m7a | Created | NA | NA |
-0.21 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr21:g.32002387C>T | COSN14596625 | 8052598 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1911-3p |
tgtGCCTGGTcttatgtaa |
0 | CACCAGGC | m7b | (m6b->m7b) | no TS | -0.100000 |
0.300000 |
|
| hsa-miR-3667-5p |
tgtgcctGGTCTTatgtaa |
1 |
AAAGACCC | m6b | Created | -0.152000 | -0.111000 | No effect | |
| hsa-miR-4645-5p |
tgTGCCTGGTcttatgtaa |
0 | ACCAGGCA | m8a | (m7a->m8a) | -0.017000 | -0.044000 |
-0.010000 |
|
| hsa-miR-4753-5p |
tgtgccTGGCCTTatgtaa |
0 | CAAGGCCA | m7b | Disrupted | 0.022000 | no TS |
-1.950000 |
|
| hsa-miR-4755-3p |
tgtGCCTGGCcttatgtaa |
0 | AGCCAGGC | m7b | (m7b->m6b) | -0.307000 | -0.238000 | No effect | |
| hsa-miR-548ao-3p |
tgtgcctGGTCTTatgtaa |
0 | AAAGACCG | m6b | Created | no TS | 0.008000 |
-0.010000 |
|
| hsa-miR-1911-3p |
tgtGCCTGGTcttatgtaa |
0 | CACCAGGC | m7b | (m6b->m7b) | no TS | -0.100000 |
0.300000 |
|
| hsa-miR-3667-5p |
tgtgcctGGTCTTatgtaa |
1 |
AAAGACCC | m6b | Created | -0.152000 | -0.111000 | No effect | |
| hsa-miR-4645-5p |
tgTGCCTGGTcttatgtaa |
0 | ACCAGGCA | m8a | (m7a->m8a) | -0.017000 | -0.044000 |
-0.010000 |
|
| hsa-miR-4753-5p |
tgtgccTGGCCTTatgtaa |
0 | CAAGGCCA | m7b | Disrupted | 0.022000 | no TS |
-1.950000 |
|
| hsa-miR-4755-3p |
tgtGCCTGGCcttatgtaa |
0 | AGCCAGGC | m7b | (m7b->m6b) | -0.307000 | -0.238000 | No effect | |
| hsa-miR-548ao-3p |
tgtgcctGGTCTTatgtaa |
0 | AAAGACCG | m6b | Created | no TS | 0.008000 |
-0.010000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr21:g.32003959G>A | COSN7144523 | 8030340 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-340-5p |
tagCTTTATAtggagcaaa |
1 |
UUAUAAAG | m7b | (m6b->m7b) | 0.310000 | 0.319000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr21:g.32003970T>G | COSN8903636 | SS6003317 | [oesophagus][NS][carcinoma][adenocarcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1282 |
ggaGCAAACGtgaggatca |
0 | UCGUUUGC | m7b | (m6b->m7b) | no TS | -0.261000 |
-0.070000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr21:g.32004054G>C | COSN10025673 | C0037T | [kidney][NS][other][neoplasm] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-660-5p |
aataAATGGGTctgacttc |
3 |
UACCCAUU | m7b | Disrupted | -0.274000 | no TS |
0.040000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 31999195 | rs2073360 | C | |||||||
| T |
hsa-miR-193a-3p hsa-miR-193b-3p hsa-miR-4286 |
2 2 5 |
GGCCAGTggggtt GGCCAGTggggtt ggccAGTGGGGtt |
Created Created Created |
N N N |
No Change No Change No Change |
|||
| 32000663 | rs28438002 | A | A |
hsa-miR-1269a hsa-miR-1269b hsa-miR-1288-3p hsa-miR-212-5p hsa-miR-3189-3p hsa-miR-362-5p hsa-miR-4515 hsa-miR-4529-3p hsa-miR-4740-5p hsa-miR-5009-5p hsa-miR-500b-5p hsa-miR-8058 |
0 |
CAGTCCAAggatc CAGTCCAAggatc CAGTCCAaggatc cagtCCAAGGAtc cagtCCAAGGAtc cagtcCAAGGATc CAGTCCAaggatc cAGTCCAAggatc CAGTCCAaggatc cAGTCCAAggatc cagtcCAAGGATc cAGTCCAAggatc |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N N N N N |
-0.056 -0.077 -0.028 0.013 0.011 0.081 0.002 0.02 -0.048 -0.001 0.062 0.006 |
| G |
hsa-miR-3917 |
0 |
caGTCCGAGgatc |
Created |
N |
-0.125 |
|||
| 32000664 | rs2833599 | T | A |
hsa-miR-1269a hsa-miR-1269b hsa-miR-212-5p hsa-miR-3189-3p hsa-miR-362-5p hsa-miR-4529-3p hsa-miR-5009-5p hsa-miR-500b-5p hsa-miR-8058 |
0 |
AGTCCAAggatcc AGTCCAAggatcc agtCCAAGGAtcc agtCCAAGGAtcc agtcCAAGGATcc AGTCCAAggatcc AGTCCAAggatcc agtcCAAGGATcc AGTCCAAggatcc |
Created Created Created Created Created Created Created Created Created |
N N N N N N N N N |
-0.022 -0.024 0.013 0.011 0.081 0.02 -0.001 0.062 0.006 |
| 32000714 | rs80302584 | G | G |
hsa-miR-4722-3p hsa-miR-4755-3p hsa-miR-4763-5p hsa-miR-5006-5p hsa-miR-6727-3p hsa-miR-7113-5p |
2 3 8 3 2 1 |
ttcccTGGCAGGc ttcCCTGGCAggc ttccctGGCAGGC ttcCCTGGCAggc ttcccTGGCAGGc tTCCCTGGcaggc |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N |
0.068 -0.023 -0.092 -0.005 0.068 -0.028 |
| C |
hsa-miR-381-5p hsa-miR-4737 hsa-miR-6068 |
3 3 6 |
ttcCCTCGCAggc ttcCCTCGCAggc ttccCTCGCAGgc |
Created Created Created |
N N N |
-0.093 -0.05 -0.033 |
|||
| 32001294 | rs9975199 | C | C |
hsa-miR-142-5p hsa-miR-320a hsa-miR-320b hsa-miR-320c hsa-miR-320d hsa-miR-340-5p hsa-miR-4429 hsa-miR-5590-3p hsa-miR-6796-3p hsa-miR-9-3p |
1 1 1 1 1 1 1 1 2 1 |
atagagCTTTATA atagAGCTTTAta atagAGCTTTAta atagAGCTTTAta atagAGCTTTAta atagagCTTTATA atagAGCTTTAta atagagCTTTATA atAGAGCTTtata atagAGCTTTAta |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N N N |
0.143 0.06 0.06 0.06 0.06 0.094 0.063 0.133 -0.079 0.055 |
| T |
hsa-miR-3163 hsa-miR-548a-3p hsa-miR-548ar-3p hsa-miR-548az-3p hsa-miR-548e-3p hsa-miR-548f-3p hsa-miR-5582-3p hsa-miR-618 |
1 1 1 1 1 1 1 2 |
atagagTTTTATA atagAGTTTTAta atagAGTTTTAta atagAGTTTTAta atagAGTTTTAta atagAGTTTTAta atagAGTTTTAta aTAGAGTTttata |
Created Created Created Created Created Created Created Created |
N N N N N N N N |
0.231 0.119 0.112 0.116 0.116 0.116 0.133 -0.047 |
|||
| 32002380 | rs2409426 | C | T |
hsa-miR-128-3p hsa-miR-216a-3p hsa-miR-3681-3p hsa-miR-4269 hsa-miR-4645-5p hsa-miR-4673 hsa-miR-5582-5p hsa-miR-6715b-5p |
0 |
cCACTGTGcctgg cCACTGTGcctgg cCACTGTGcctgg ccactGTGCCTGg ccactgTGCCTGG ccactgTGCCTGG ccacTGTGCCTgg ccactGTGCCTGg |
Created Created Created Created Created Created Created Created |
N N N N N N N N |
0.136 0.127 0.127 0.007 0.045 0.027 0.099 -0.003 |
| 32003390 | rs138904949 | - | T | 0 |
|
||||
| - |
hsa-miR-103b hsa-miR-1273d |
4 3 |
aGGCTATGggtt aggctATGGGTT |
Unknown Unknown |
N N |
-0.21 -0.164 |
|||
| 32004037 | rs76143729 | G | G |
hsa-miR-3622a-3p hsa-miR-3622b-3p hsa-miR-5096 hsa-miR-6765-3p |
13 13 13 13 |
ttaCAGGTGAaaa ttaCAGGTGAaaa ttacaGGTGAAAA ttaCAGGTGAaaa |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.203 -0.196 -0.357 -0.19 |
| A |
hsa-miR-335-3p hsa-miR-3607-3p hsa-miR-3686 hsa-miR-452-3p |
14 8 8 13 |
ttacagATGAAAA TTACAGAtgaaaa TTACAGAtgaaaa ttaCAGATGAAaa |
Created Created Created Created |
N N N N |
-0.106 -0.13 -0.189 -0.41 |