SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
	Home	Search	Help	Download

Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_006948
Gene Symbol:	HSPA13
Description:	Homo sapiens heat shock protein 70kDa family, member 13 (HSPA13), mRNA.
Gene Location:	chr21(-):15743436-15755509
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr21:g.14371710C>T			0_591				Melanoma
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-191-5p	ctcttaaTCCGTTaatgct	0	CAACGGAA	m6b	Disrupted	-0.338	-0.171	0.06

Mutation			Mutation ID		Sample Name		Cancer Type
chr21:g.14371860A>G			COSN5978777		RK186_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-5683	taaATCTGTAatagatttt	0	UACAGAUG	m7a	(m7a->m6b)	-0.057000	no TS	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr21:g.14372040A>G			COSN5448516		RK164_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-200c-5p	tgctgtTAAGACacaaatt	0	CGUCUUAC	m6b	Created	no TS	-0.035000	-6.170000
hsa-miR-302c-5p	tgcTGTTAAAacacaaatt	5	UUUAACAU	m7a	(m7a->m6b)	0.051000	no TS	0.260000
hsa-miR-4711-3p	tgctgttAAGACACaaatt	0	CGUGUCUU	m7b	Created	no TS	-0.183000	-0.380000
hsa-miR-511	tgctgttAAGACACaaatt	0	GUGUCUUU	m7a	Created	NA	NA	-0.300000
hsa-miR-592	tgctgttaaGACACAAatt	0	UUGUGUCA	m7a	(m6a->m7a)	no TS	-0.096000	-0.520000
hsa-miR-599	tgctgttaaGACACAAatt	2	GUUGUGUC	m7b	(m6b->m7b)	-0.042000	-0.197000	0.030000

Mutation			Mutation ID		Sample Name		Cancer Type
chr21:g.14372085T>C			COSN5448517		RK164_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Mutation			Mutation ID		Sample Name		Cancer Type
chr21:g.14372255A>G			COSN1882060		RK015_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4436a	aaaaattaTGTCCTGatca	0	GCAGGACA	m7b	Created	-0.516000	-0.731000	No effect
hsa-miR-5000-3p	aaaaattaTGTCCTGAtca	0	UCAGGACA	m8a	Created	-0.545000	-0.792000	-0.020000
hsa-miR-4436a	aaaaattaTGTCCTGatca	0	GCAGGACA	m7b	Created	-0.516000	-0.731000	No effect
hsa-miR-5000-3p	aaaaattaTGTCCTGAtca	0	UCAGGACA	m8a	Created	-0.545000	-0.792000	-0.020000
hsa-miR-4436a	aaaaattaTGTCCTGatca	0	GCAGGACA	m7b	Created	-0.516	-0.731	No effect
hsa-miR-5000-3p	aaaaattaTGTCCTGAtca	0	UCAGGACA	m8a	Created	-0.545	-0.792	-0.02

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
14371655	rs67720834	-	-	hsa-miR-4436a hsa-miR-5000-3p	1 1	caTGTCCTGAagt caTGTCCTGAagt	Unknown Unknown	N N	-0.304 -0.314
			C	hsa-miR-211-3p hsa-miR-3127-5p hsa-miR-4270 hsa-miR-4441 hsa-miR-6754-5p hsa-miR-7845-5p	1 1 1 1 1 1	catGTCCCTGAagt catgtCCCTGAAgt catgTCCCTGAagt catgTCCCTGAagt catgTCCCTGAagt caTGTCCCTgaagt	Unknown Unknown Unknown Unknown Unknown Unknown	N N N N N N	-0.355 -0.114 -0.118 -0.122 -0.112 -0.182

Genome Browser