SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_024501
Gene Symbol: HOXD1
Description: Homo sapiens homeobox D1 (HOXD1), mRNA.
Gene Location: chr2(+):177053306-177055635
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr2:g.176190165A>G COSN14984462 LP6005690-DNA_C01 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4328 ggccgaAAAACTGtggcct
2
CCAGUUUU m7b Disrupted 0.003000 no TS 0.110000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.176190315C>A COSN9867282 C0048T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3126-3p ctatatgtCCAGATattaa
0 CAUCUGGC m6b Disrupted -0.159000 no TS 0.470000
hsa-miR-378a-3p ctatatGTCCAGatattaa
2
ACUGGACU m6b Disrupted -0.206000 no TS 2.710000
hsa-miR-378b ctatatGTCCAGatattaa
2
ACUGGACU m6b Disrupted -0.193000 no TS 2.080000
hsa-miR-378c ctatatGTCCAGatattaa
2
ACUGGACU m6b Disrupted -0.206000 no TS 2.420000
hsa-miR-378d ctatatGTCCAGatattaa
2
ACUGGACU m6b Disrupted -0.206000 no TS 2.910000
hsa-miR-378e ctatatGTCCAGatattaa
2
ACUGGACU m6b Disrupted -0.206000 no TS 4.990000
hsa-miR-378f ctatatGTCCAGatattaa
2
ACUGGACU m6b Disrupted -0.193000 no TS 2.420000
hsa-miR-378h ctatatGTCCAGatattaa
2
ACUGGACU m6b Disrupted -0.203000 no TS 2.830000
hsa-miR-378i ctatatGTCCAGatattaa
2
ACUGGACU m6b Disrupted -0.206000 no TS 4.240000
hsa-miR-422a ctatatGTCCAGatattaa
2
ACUGGACU m6b Disrupted -0.203000 no TS 4.510000
hsa-miR-4638-3p ctataTGTCCAGatattaa
2
CCUGGACA m7b Disrupted -0.455000 no TS 2.970000
hsa-miR-489 ctatATGTCAagatattaa
0 GUGACAUC m6b Created no TS -0.098000 No effect
hsa-miR-516b-5p ctatatgTCCAGATattaa
0 AUCUGGAG m7a Disrupted NA NA 1.320000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.176190464A>G COSN15514032 AOCS-170-3-5 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3129-3p cagaccATTAGTTgctgag
11
AAACUAAU m7b Disrupted 0.006000 -0.013000 0.660000
hsa-miR-5583-5p cagaccATTAGTTgctgag
11
AAACUAAU m7b Disrupted 0.012000 -0.016000 No effect
hsa-miR-3129-3p cagaccATTAGTTgctgag
11
AAACUAAU m7b Disrupted 0.006000 -0.013000 0.660000
hsa-miR-5583-5p cagaccATTAGTTgctgag
11
AAACUAAU m7b Disrupted 0.012000 -0.016000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.176190591C>T COSN7148064 8033414 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4428 agttagggTCTCCTTGatg
5
CAAGGAGA m8a Disrupted -0.102000 no TS 2.290000
hsa-miR-4496 agttaggGTTTCCTtgatg
0 GAGGAAAC m7b Created no TS -0.085000 -9.000000
hsa-miR-652-5p agtTAGGGTTtccttgatg
0 CAACCCUA m7b (m6b->m7b) no TS -0.182000 -6.510000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.176190728C>T HOXD1_E2_UTR_3 SJHYPO052_R Hypodiploid_ALL
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-20b-3p gaacaaatCTACAGaatgg
0 ACUGUAGU m6b Created no TS -0.132 -0.05
hsa-miR-3137 gaacaaatCTACAGAatgg
0 UCUGUAGC m7a Created no TS -0.138 No effect
hsa-miR-3167 gaacAAATCCacagaatgg
8
AGGAUUUC m6b Disrupted -0.069 no TS 2.23
hsa-miR-3686 gaacaaatcTACAGAatgg
0 AUCUGUAA m6b Created no TS -0.097 -0.04
hsa-miR-3691-5p gaacaaATCCACagaatgg
8
AGUGGAUG m6b Disrupted -0.14 no TS 6.93
hsa-miR-376a-5p gaacaAATCTACagaatgg
0 GUAGAUUC m7a Created NA NA No effect
hsa-miR-4752 gaacaaATCCACAgaatgg
8
UUGUGGAU m7b Disrupted -0.215 no TS 0.68

Mutation Mutation ID Sample Name Cancer Type
chr2:g.176190736G>T COSN8608024 J11_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4778-5p ccACAGAATTggtaaagag
1
AAUUCUGU m8a (m7a->m8a) -0.063000 -0.090000 -0.490000
hsa-miR-5591-3p ccacagaATGGGTAaagag
1
AUACCCAU m7b Disrupted -0.369000 no TS 4.000000
hsa-miR-660-5p ccacagAATGGGTAaagag
1
UACCCAUU m8a Disrupted -0.348000 no TS 3.050000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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