| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_004133 |
|---|---|
| Gene Symbol: | HNF4G |
| Description: | Homo sapiens hepatocyte nuclear factor 4, gamma (HNF4G), mRNA. |
| Gene Location: | chr8(+):76452202-76479061 |
| Browse Associations | |
| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr8:g.75564420T>A | COSN6363119 | RK308_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-2681-5p |
atctGTAAAAaattgcttt |
0 | GUUUUACC | m6b | Created | 0.075000 | 0.061000 | No effect | |
| hsa-miR-4699-3p |
atctGTAAATaattgcttt |
17 |
AAUUUACU | m6b | Disrupted | -0.022000 | no TS | No effect | |
| hsa-miR-944 |
atctgtaAATAATTgcttt |
12 |
AAAUUAUU | m7b | Disrupted | -0.060000 | -0.030000 |
0.020000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr8:g.75564683C>A | COSN15325523 | 0077_CRUK_PC_0077_T1_DNA | [prostate][NS][carcinoma][adenocarcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1 |
tacaaaaaaACATTCCAag |
0 | UGGAAUGU | m8a | (m7b->m8a) | -0.091000 | -0.278000 |
-1.060000 |
|
| hsa-miR-206 |
tacaaaaaaACATTCCAag |
0 | UGGAAUGU | m8a | (m7b->m8a) | -0.084000 | -0.257000 |
-1.150000 |
|
| hsa-miR-33a-3p |
tacaaaaAAACATTccaag |
0 | CAAUGUUU | m7b | Created | 0.111000 | 0.092000 |
-0.010000 |
|
| hsa-miR-4307 |
tacaaaAAAACATTccaag |
3 |
AAUGUUUU | m8a | Created | 0.177000 | 0.130000 |
-0.740000 |
|
| hsa-miR-4790-3p |
tacaaaaaACCATTCcaag |
3 |
UGAAUGGU | m7b | Disrupted | -0.170000 | no TS |
0.140000 |
|
| hsa-miR-613 |
tacaaaaaaACATTCCaag |
0 | AGGAAUGU | m7b | (m6c->m7b) | -0.087000 | -0.268000 |
-0.250000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr8:g.75564684C>T | COSN9679710 | AOCS-109-1-X | [ovary][NS][other][neoplasm] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1 |
acaaaaaacCATTCCAagg |
0 | UGGAAUGU | m7a | (m7a->m6b) | -0.091000 | no TS |
0.530000 |
|
| hsa-miR-206 |
acaaaaaacCATTCCAagg |
0 | UGGAAUGU | m7a | (m7a->m6b) | -0.084000 | no TS |
0.690000 |
|
| hsa-miR-3673 |
acaaaaaacCATTCCAagg |
0 | AUGGAAUG | m7b | (m7b->m6c) | -0.151000 | -0.024000 |
1.320000 |
|
| hsa-miR-4790-3p |
acaaaaaACCATTCcaagg |
3 |
UGAAUGGU | m7b | Disrupted | -0.170000 | no TS |
0.130000 |
|
| hsa-miR-613 |
acaaaaaacCATTCCaagg |
0 | AGGAAUGU | m6b | Disrupted | -0.087000 | no TS |
-0.240000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr8:g.75565031C>G | COSN9679711 | AOCS-158-1-6 | [ovary][NS][other][neoplasm] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1224-5p |
tttgGTCCTCACaataaca |
3 |
GUGAGGAC | m8a | Disrupted | -0.127000 | no TS |
4.910000 |
|
| hsa-miR-1294 |
tttggtCCTCACAataaca |
6 |
UGUGAGGU | m7a | Disrupted | -0.079000 | no TS |
0.810000 |
|
| hsa-miR-4316 |
tttggtCCTCACaataaca |
6 |
GGUGAGGC | m6b | Disrupted | -0.074000 | no TS |
0.160000 |
|
| hsa-miR-4436a |
tttgGTCCTGacaataaca |
0 | GCAGGACA | m6b | Created | no TS | -0.090000 |
-1.830000 |
|
| hsa-miR-4751 |
tttGGTCCTCacaataaca |
1 |
AGAGGACC | m7b | (m7b->m6b) | -0.308000 | no TS |
1.540000 |
|
| hsa-miR-5701 |
tttggtcctGACAATAAca |
2 |
UUAUUGUC | m8a | (m7b->m8a) | 0.065000 | -0.002000 |
-0.650000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr8:g.75565108C>G | COSN9679712 | AOCS-163-1-4 | [ovary][NS][other][neoplasm] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-141-5p |
tttaaGGAAGATaaccaaa |
0 | CAUCUUCC | m7b | Created | no TS | -0.125000 |
-0.100000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr8:g.75565356C>A | COSN2289638 | RK001_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1264 |
agttttaacAAGACTTtct |
0 | CAAGUCUU | m7b | (m6c->m7b) | no TS | 0.020000 |
0.790000 |
|
| hsa-miR-2053 |
agttTTAACAagactttct |
0 | GUGUUAAU | m6b | Created | no TS | 0.084000 | No effect | |
| hsa-miR-29b-1-5p |
agttttAACCAGactttct |
0 | GCUGGUUU | m6b | Disrupted | -0.010000 | no TS |
3.750000 |
|
| hsa-miR-1264 |
agttttaacAAGACTTtct |
0 | CAAGUCUU | m7b | (m6c->m7b) | no TS | 0.02 |
0.79 |
|
| hsa-miR-2053 |
agttTTAACAagactttct |
0 | GUGUUAAU | m6b | Created | no TS | 0.084 | No effect | |
| hsa-miR-29b-1-5p |
agttttAACCAGactttct |
0 | GCUGGUUU | m6b | Disrupted | -0.01 | no TS |
3.75 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr8:g.75566028C>T | COSN9679713 | AOCS-064-1-6 | [ovary][NS][other][neoplasm] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3914 |
gggGGTTCCTTtagaagac |
0 | AAGGAACC | m8a | Created | no TS | -0.129000 |
-2.520000 |
|
| hsa-miR-4263 |
gggggttccCTTAGAAgac |
8 |
AUUCUAAG | m7b | (m7b->m6c) | 0.095000 | 0.033000 | No effect | |
| hsa-miR-4475 |
gggggtTCCCTTagaagac |
2 |
CAAGGGAC | m6b | Disrupted | -0.233000 | -0.186000 |
-0.010000 |
|
| hsa-miR-4509 |
gggggttCCTTTAGaagac |
2 |
ACUAAAGG | m7b | Created | -0.042000 | -0.171000 |
-1.260000 |
|
| hsa-miR-4521 |
gggggttcCCTTAGaagac |
2 |
GCUAAGGA | m6b | Disrupted | -0.054000 | no TS | No effect | |
| hsa-miR-4744 |
gggggttcCTTTAGAagac |
2 |
UCUAAAGA | m7a | Created | -0.032000 | -0.017000 |
-0.010000 |
|
| hsa-miR-4799-5p |
gggggttccTTTAGAagac |
5 |
AUCUAAAU | m6b | Created | -0.042000 | 0.032000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr8:g.75566568T>G | COSN9679714 | AOCS-133-1-9 | [ovary][NS][other][neoplasm] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-570-3p |
aggaactgaTGTTTTCagc |
8 |
CGAAAACA | m7b | (m7b->m6c) | -0.158000 | -0.011000 |
0.050000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 75564670 | rs117918767 | A | A |
hsa-miR-4263 hsa-miR-4799-5p hsa-miR-576-5p |
8 5 8 |
tTTAGAAAaatac TTTAGAAaaatac tTTAGAAAaatac |
Disrupted Disrupted Disrupted |
N N N |
0.006 -0.012 0.014 |
| G |
hsa-miR-4684-5p hsa-miR-4768-5p hsa-miR-520f-5p hsa-miR-6809-3p hsa-miR-6833-3p |
8 2 5 2 2 |
ttTAGAGAAatac tttAGAGAAAtac TTTAGAGAaatac tttAGAGAAAtac tttAGAGAAAtac |
Created Created Created Created Created |
N N N N N |
-0.076 -0.037 -0.155 -0.041 -0.05 |
|||
| 75564671 | rs188803761 | A | A |
hsa-miR-4263 hsa-miR-576-5p |
8 8 |
TTAGAAAaataca TTAGAAAaataca |
Disrupted Disrupted |
N N |
0.006 0.014 |
| G |
hsa-miR-4659a-3p hsa-miR-4659b-3p hsa-miR-630 |
2 2 2 |
ttAGAAGAAtaca ttAGAAGAAtaca ttagaAGAATACA |
Created Created Created |
N N N |
-0.104 -0.104 -0.203 |
|||
| 75565129 | rs143615065 | T | T |
hsa-miR-4307 |
1 |
cAAACATAacgag |
Disrupted |
N |
0.095 |
| 75565340 | rs73692613 | C | C |
hsa-miR-140-5p hsa-miR-4796-3p hsa-miR-548az-5p hsa-miR-548t-5p |
3 3 3 3 |
aAACCACTtttgt aaaCCACTTTtgt aaacCACTTTTgt aaacCACTTTTgt |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.101 -0.073 0.081 0.081 |
| G |
hsa-miR-1323 hsa-miR-29b-1-5p hsa-miR-548a-3p hsa-miR-548ar-3p hsa-miR-548az-3p hsa-miR-548e-3p hsa-miR-548f-3p hsa-miR-548o-3p hsa-miR-582-3p |
3 3 3 3 3 3 3 3 3 |
aaaccAGTTTTGt AAACCAGttttgt aaacCAGTTTTgt aaacCAGTTTTgt aaacCAGTTTTgt aaacCAGTTTTgt aaacCAGTTTTgt aaaccAGTTTTGt aaACCAGTTttgt |
Created Created Created Created Created Created Created Created Created |
N N N N N N N N N |
0.068 -0.037 0.051 0.029 0.059 0.059 0.059 0.049 -0.102 |
|||
| 75565352 | rs199888487 | T | T |
hsa-miR-548a-3p hsa-miR-548ar-3p hsa-miR-548az-3p hsa-miR-548e-3p hsa-miR-548f-3p hsa-miR-5582-3p |
1 1 1 1 1 1 |
tAGTTTTAaccag tAGTTTTAaccag tAGTTTTAaccag tAGTTTTAaccag tAGTTTTAaccag tAGTTTTAaccag |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N |
0.131 0.128 0.128 0.128 0.128 0.118 |
| A |
hsa-miR-299-5p hsa-miR-29b-1-5p hsa-miR-7844-5p |
0 |
tagttTAAACCAg tagtttAAACCAG TAGTTTAaaccag |
Created Created Created |
N N N |
0.025 -0.045 0.053 |
|||
| 75565354 | rs201207943 | A | A |
hsa-miR-29b-1-5p |
0 |
gttttAACCAGAc |
Disrupted |
N |
-0.01 |
| T |
hsa-miR-1261 hsa-miR-378j hsa-miR-4782-5p hsa-miR-5706 hsa-miR-6839-5p |
0 |
gttTTATCCAgac gttttATCCAGAc gttttATCCAGAc gttttATCCAGAc gttttATCCAGAc |
Created Created Created Created Created |
N N N N N |
-0.024 -0.034 -0.108 -0.089 -0.034 |
|||
| 75565355 | rs1515020 | C | C |
hsa-miR-29b-1-5p |
0 |
ttttAACCAGAct |
Disrupted |
N |
-0.01 |
| T |
hsa-miR-29a-5p hsa-miR-3920 |
0 |
ttttAATCAGAct tttTAATCAGAct |
Created Created |
N N |
0.043 -0.047 |
|||
| 75565358 | rs191724665 | G | G |
hsa-miR-29b-1-5p |
0 |
tAACCAGActttc |
Disrupted |
N |
-0.01 |
| C |
hsa-miR-1273g-5p hsa-miR-595 |
0 |
tAACCACActttc taacCACACTTtc |
Created Created |
N N |
-0.035 -0.021 |