SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_002123
Gene Symbol: HLA-DQB1
Description: Homo sapiens major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1), transcript variant 2, mRNA.
Gene Location: chr6(-):32627656-32634466
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr6:g.32659758C>A COSN6513866 HCC17T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3160-5p cactGAAAGCattttgggg
 0 GGCUUUCU m6b Disrupted -0.442000 -0.369000 1.230000
hsa-miR-4698 cactgaaagCATTTTGggg
 0 UCAAAAUG m7b (m7b->m6b) 0.051000 no TS 2.140000
hsa-miR-3160-5p cactGAAAGCattttgggg
 0 GGCUUUCU m6b Disrupted -0.442000 -0.369000 1.230000
hsa-miR-4698 cactgaaagCATTTTGggg
 0 UCAAAAUG m7b (m7b->m6b) 0.051000 no TS 2.140000

Mutation Mutation ID Sample Name Cancer Type
chr6:g.32660000C>G COSN1331683 HCC141T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-199a-3p gcgtCTACTGaggtcccaa
 0 ACAGUAGU m6b Created no TS -0.050000 -1.740000
hsa-miR-199b-3p gcgtCTACTGaggtcccaa
 0 ACAGUAGU m6b Created no TS -0.050000 -1.740000
hsa-miR-222-5p gcgtCTACTGAGgtcccaa
 0 CUCAGUAG m8a Created no TS -0.067000 -3.170000
hsa-miR-3129-5p gcgtCTACTGaggtcccaa
 0 GCAGUAGU m6b Created no TS -0.050000 -11.030000
hsa-miR-4797-3p gcgtcTACTGAGgtcccaa
 0 UCUCAGUA m7b Created no TS -0.078000 -7.050000
hsa-miR-492 gcgtctactCAGGTCCcaa
 1
 AGGACCUG m7b (m7b->m6b) -0.239000 no TS 2.060000
hsa-miR-936 gcgTCTACTGaggtcccaa
 0 ACAGUAGA m7b (m6c->m7b) no TS -0.168000 -3.490000
hsa-miR-199a-3p gcgtCTACTGaggtcccaa
 0 ACAGUAGU m6b Created no TS -0.05 -1.74
hsa-miR-199b-3p gcgtCTACTGaggtcccaa
 0 ACAGUAGU m6b Created no TS -0.05 -1.74
hsa-miR-222-5p gcgtCTACTGAGgtcccaa
 0 CUCAGUAG m8a Created no TS -0.067 -3.17
hsa-miR-3129-5p gcgtCTACTGaggtcccaa
 0 GCAGUAGU m6b Created no TS -0.05 -11.03
hsa-miR-4797-3p gcgtcTACTGAGgtcccaa
 0 UCUCAGUA m7b Created no TS -0.078 -7.05
hsa-miR-492 gcgtctactCAGGTCCcaa
 0 AGGACCUG m7b (m7b->m6b) -0.239 no TS 2.06
hsa-miR-936 gcgTCTACTGaggtcccaa
 0 ACAGUAGA m7b (m6c->m7b) no TS -0.168 -3.49

Mutation Mutation ID Sample Name Cancer Type
chr6:g.32660041G>T COSN1331684 BN13T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-130a-3p tccTGCACTGacccagagc
 0 CAGUGCAA m7a (m7a->m6b) NA NA No effect
hsa-miR-130b-3p tccTGCACTGacccagagc
 0 CAGUGCAA m7a (m7a->m6b) NA NA No effect
hsa-miR-148a-3p tccTGCACTGAcccagagc
 5
 UCAGUGCA m8a Disrupted -0.267000 no TS 0.420000
hsa-miR-148b-3p tccTGCACTGAcccagagc
 5
 UCAGUGCA m8a Disrupted -0.267000 no TS 5.670000
hsa-miR-152 tccTGCACTGAcccagagc
 5
 UCAGUGCA m8a Disrupted -0.267000 no TS 4.610000
hsa-miR-301a-3p tccTGCACTGacccagagc
 0 CAGUGCAA m7a (m7a->m6b) NA NA -0.050000
hsa-miR-301b tccTGCACTGacccagagc
 0 CAGUGCAA m7a (m7a->m6b) NA NA -0.040000
hsa-miR-3666 tccTGCACTGacccagagc
 0 CAGUGCAA m7a (m7a->m6b) NA NA -0.050000
hsa-miR-372 tcctGCACTTacccagagc
 0 AAAGUGCU m6b Created no TS -0.032000 -1.910000
hsa-miR-373-3p tcctGCACTTacccagagc
 0 GAAGUGCU m6b Created no TS -0.025000 -3.280000
hsa-miR-4295 tccTGCACTGacccagagc
 0 CAGUGCAA m7a (m7a->m6b) NA NA No effect
hsa-miR-4697-3p tcctgCACTGACccagagc
 4
 UGUCAGUG m7b Disrupted -0.089000 no TS 12.870000
hsa-miR-519a-3p tccTGCACTTacccagagc
 0 AAAGUGCA m7b (m6c->m7b) no TS -0.202000 -4.820000
hsa-miR-519b-3p tccTGCACTTacccagagc
 0 AAAGUGCA m7b (m6c->m7b) no TS -0.192000 -0.760000
hsa-miR-519c-3p tccTGCACTTacccagagc
 0 AAAGUGCA m7b (m6c->m7b) no TS -0.192000 -1.050000
hsa-miR-520a-3p tcctGCACTTacccagagc
 0 AAAGUGCU m6b Created no TS -0.025000 -0.010000
hsa-miR-520b tcctGCACTTacccagagc
 0 AAAGUGCU m6b Created no TS -0.035000 -0.010000
hsa-miR-520c-3p tcctGCACTTacccagagc
 0 AAAGUGCU m6b Created no TS -0.035000 -0.010000
hsa-miR-520d-3p tcctGCACTTacccagagc
 0 AAAGUGCU m6b Created no TS -0.025000 No effect
hsa-miR-520e tcctGCACTTacccagagc
 0 AAAGUGCU m6b Created no TS -0.029000 No effect
hsa-miR-555 tcctgcaCTTACCCagagc
 0 AGGGUAAG m7b Created no TS -0.295000 -1.800000
hsa-miR-130a-3p tccTGCACTGacccagagc
 0 CAGUGCAA m7a (m7a->m6b) NA NA No effect
hsa-miR-130b-3p tccTGCACTGacccagagc
 0 CAGUGCAA m7a (m7a->m6b) NA NA No effect
hsa-miR-148a-3p tccTGCACTGAcccagagc
 0 UCAGUGCA m8a Disrupted -0.267 no TS 0.42
hsa-miR-148b-3p tccTGCACTGAcccagagc
 0 UCAGUGCA m8a Disrupted -0.267 no TS 5.67
hsa-miR-152 tccTGCACTGAcccagagc
 0 UCAGUGCA m8a Disrupted -0.267 no TS 4.61
hsa-miR-301a-3p tccTGCACTGacccagagc
 0 CAGUGCAA m7a (m7a->m6b) NA NA -0.05
hsa-miR-301b tccTGCACTGacccagagc
 0 CAGUGCAA m7a (m7a->m6b) NA NA -0.04
hsa-miR-3666 tccTGCACTGacccagagc
 0 CAGUGCAA m7a (m7a->m6b) NA NA -0.05
hsa-miR-372 tcctGCACTTacccagagc
 0 AAAGUGCU m6b Created no TS -0.032 -1.91
hsa-miR-373-3p tcctGCACTTacccagagc
 0 GAAGUGCU m6b Created no TS -0.025 -3.28
hsa-miR-4295 tccTGCACTGacccagagc
 0 CAGUGCAA m7a (m7a->m6b) NA NA No effect
hsa-miR-4697-3p tcctgCACTGACccagagc
 0 UGUCAGUG m7b Disrupted -0.089 no TS 12.87
hsa-miR-519a-3p tccTGCACTTacccagagc
 0 AAAGUGCA m7b (m6c->m7b) no TS -0.202 -4.82
hsa-miR-519b-3p tccTGCACTTacccagagc
 0 AAAGUGCA m7b (m6c->m7b) no TS -0.192 -0.76
hsa-miR-519c-3p tccTGCACTTacccagagc
 0 AAAGUGCA m7b (m6c->m7b) no TS -0.192 -4.73
hsa-miR-520a-3p tcctGCACTTacccagagc
 0 AAAGUGCU m6b Created no TS -0.025 -0.01
hsa-miR-520b tcctGCACTTacccagagc
 0 AAAGUGCU m6b Created no TS -0.035 -0.01
hsa-miR-520c-3p tcctGCACTTacccagagc
 0 AAAGUGCU m6b Created no TS -0.035 -0.01
hsa-miR-520d-3p tcctGCACTTacccagagc
 0 AAAGUGCU m6b Created no TS -0.025 No effect
hsa-miR-520e tcctGCACTTacccagagc
 0 AAAGUGCU m6b Created no TS -0.029 No effect
hsa-miR-555 tcctgcaCTTACCCagagc
 0 AGGGUAAG m7b Created no TS -0.295 -1.8


Mutation Mutation ID Sample Name Cancer Type
chr6:g.32660056T>C COSN1331685 BN13T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr6:g.32660179G>C COSN167742 GC8_T [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1207-5p cctgcttatCCCTGCCcag
 0 UGGCAGGG m7b (m6b->m7b) no TS -0.273000 -3.210000
hsa-miR-4763-3p cctgcttatCCCTGCCcag
 0 AGGCAGGG m7b (m6b->m7b) no TS -0.273000 No effect
hsa-miR-1207-5p cctgcttatCCCTGCCcag
 0 UGGCAGGG m7b (m6b->m7b) no TS -0.273000 -3.210000
hsa-miR-4763-3p cctgcttatCCCTGCCcag
 0 AGGCAGGG m7b (m6b->m7b) no TS -0.273000 No effect
hsa-miR-1207-5p cctgcttatCCCTGCCcag
 0 UGGCAGGG m7b (m6b->m7b) no TS -0.273 -3.21
hsa-miR-4763-3p cctgcttatCCCTGCCcag
 0 AGGCAGGG m7b (m6b->m7b) no TS -0.273 No effect

Mutation Mutation ID Sample Name Cancer Type
chr6:g.32660181A>G COSN8892470 B89-4-Tumor [urinary_tract][bladder][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4269 tgcctgcttGTGCCTGCcc
 0 GCAGGCAC m8a (m7a->m8a) no TS -0.208000 -0.050000
hsa-miR-5582-5p tgcctgctTGTGCCTgccc
 0 UAGGCACA m7b Created no TS -0.159000 -5.480000

Mutation Mutation ID Sample Name Cancer Type
chr6:g.32660211T>C COSN167743 GC8_T [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1910 taactAGGACTGGttatca
 0 CCAGUCCU m8a Created no TS -0.246000 No effect
hsa-miR-1910 taactAGGACTGGttatca
 0 CCAGUCCU m8a Created no TS -0.246 No effect


Mutation Mutation ID Sample Name Cancer Type
chr6:g.32660214G>A COSN167744 GC8_T [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr6:g.32660224A>G COSN167745 GC8_T [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-132-3p cctgaGACTGTTttaacta
 0 UAACAGUC m7b Created no TS 0.000000 No effect
hsa-miR-212-3p cctgaGACTGTTttaacta
 0 UAACAGUC m7b Created no TS 0.000000 No effect
hsa-miR-4474-5p cctGAGACTAttttaacta
 0 UUAGUCUC m7b (m7b->m6c) 0.000000 no TS No effect
hsa-miR-132-3p cctgaGACTGTTttaacta
 0 UAACAGUC m7b Created no TS 0 No effect
hsa-miR-212-3p cctgaGACTGTTttaacta
 0 UAACAGUC m7b Created no TS 0 No effect
hsa-miR-4474-5p cctGAGACTAttttaacta
 0 UUAGUCUC m7b (m7b->m6c) 0 no TS No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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