SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_020760
Gene Symbol: HECW2
Description: Homo sapiens HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 (HECW2), mRNA.
Gene Location: chr2(-):197063976-197457335
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr2:g.196199575G>A COSN6162644 RK308_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-337-3p tcctatTATAGGAtgttgg
0 CUCCUAUA m7b Created no TS -0.157000 -0.100000
hsa-miR-374a-5p tccTATTATAggatgttgg
0 UUAUAAUA m7b (m6c->m7b) no TS 0.062000 -0.002000
hsa-miR-374b-5p tccTATTATAggatgttgg
0 AUAUAAUA m7b (m6c->m7b) no TS 0.071000 -0.020000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.196199667G>A COSN8608287 783_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2053 cattggATTAACAtatggt
0 GUGUUAAU m7b Created no TS -0.011000 -0.290000
hsa-miR-569 cattggATTAACatatggt
0 AGUUAAUG m6b Created no TS -0.002000 -0.040000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.196200816A>C COSN15090522 SM-4B296 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2909 taaGCCCTAAgttataaca
0 GUUAGGGC m7b (m7b->m6c) -0.280000 no TS 8.860000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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