SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_145740 |
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Gene Symbol: | GSTA1 |
Description: | Homo sapiens glutathione S-transferase alpha 1 (GSTA1), mRNA. |
Gene Location: | chr6(-):52656177-52668664 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr6:g.52791482A>T | COSN14460590 | 8068554 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-19a-3p |
ttttcaggTTTGCACAgga |
0 | UGUGCAAA | m8a | Created | no TS | -0.236000 |
-3.880000 |
|
hsa-miR-19b-3p |
ttttcaggTTTGCACAgga |
0 | UGUGCAAA | m8a | Created | no TS | -0.236000 |
-2.310000 |
|
hsa-miR-548aw |
ttttcaggTTTGCACagga |
1 |
GUGCAAAA | m7a | Created | -0.221000 | -0.221000 | No effect | |
hsa-miR-5689 |
ttttcagGTATGCacagga |
0 | AGCAUACA | m6b | Disrupted | -0.143000 | no TS |
0.330000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr6:g.52791675A>C | COSN9797163 | AOCS-137-3-7 | [ovary][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4454 |
gttttcatTCGGATCtgat |
0 | GGAUCCGA | m7b | Created | no TS | -0.324000 |
-5.520000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr6:g.52791764G>C | COSN5811093 | EOPC-011_tumor | [prostate][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4773 |
gtgcCTGTTCTGaagctaa |
0 | CAGAACAG | m8a | Created | -0.093000 | -0.212000 |
-4.060000 |
|
hsa-miR-5003-5p |
gtgccTGTTGTGAagctaa |
1 |
UCACAACA | m8a | Disrupted | -0.272000 | no TS |
1.630000 |
|
hsa-miR-589-3p |
gtgccTGTTCTGAagctaa |
0 | UCAGAACA | m8a | Created | no TS | -0.240000 |
-6.730000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr6:g.52791801A>T | COSN9908948 | C0010T | [kidney][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4684-3p |
ttTTGCAACAataaagtac |
1 |
UGUUGCAA | m8a | (m8a->m7b) | -0.422000 | -0.270000 |
-0.210000 |
hsa-miR-5701 |
ttttgcaACAATAAagtac |
0 | UUAUUGUC | m7a | Disrupted | -0.052000 | no TS |
-0.170000 |
hsa-miR-744-3p |
ttttGCAACAataaagtac |
2 |
CUGUUGCC | m6b | Disrupted | -0.179000 | no TS |
-0.190000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
52791798 | rs699334 | A | A |
hsa-miR-5701 |
4 |
aACAATAAagtac |
Disrupted |
N |
-0.052 |
52791801 | rs73740640 | A | A |
hsa-miR-4684-3p hsa-miR-5701 hsa-miR-744-3p |
1 4 2 |
TGCAACAataaag tgcaACAATAAag tGCAACAAtaaag |
Disrupted Disrupted Disrupted |
N N N |
-0.179 -0.052 -0.179 |
C |
hsa-miR-218-2-3p hsa-miR-584-5p hsa-miR-656-5p hsa-miR-758-5p |
3 3 2 2 |
tgcAACCATAaag tgcAACCATAAag tGCAACCAtaaag tgCAACCATAaag |
Created Created Created Created |
N N N N |
-0.129 -0.274 -0.239 -0.374 |
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52791819 | rs1052027 | G | G |
hsa-miR-4773 hsa-miR-5687 |
1 21 |
accaaTGTTCTAa accaatGTTCTAA |
Disrupted Disrupted |
N N |
-0.093 -0.135 |