SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001191323
Gene Symbol: GREM1
Description: Homo sapiens gremlin 1 (GREM1), transcript variant 3, mRNA.
Gene Location: chr15(+):33010204-33026870
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr15:g.32731634C>T COSN8589809 J90_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2114-3p gaaGAGGCTCctctgaggg
 2
 CGAGCCUC m7b (m7b->m6b) -0.211000 no TS 0.010000
hsa-miR-3123 gaagaggcTTCTCTGaggg
 0 CAGAGAAU m7a Created NA NA No effect
hsa-miR-3919 gaagaggcTTCTCTGaggg
 3
 GCAGAGAA m7b Created -0.145000 -0.211000 -0.010000
hsa-miR-4257 gaagaggctCCTCTGaggg
 2
 CCAGAGGU m6b Disrupted -0.052000 0.009000 No effect
hsa-miR-4756-3p gaagaggctTCTCTGaggg
 3
 CCAGAGAU m6b Created -0.045000 -0.085000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr15:g.32732001A>C COSN8741984 AOCS-058-1-5 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-298 atgCTTCTGCgaaagtctt
 0 AGCAGAAG m7b (m6b->m7b) no TS -0.064000 No effect
hsa-miR-4330 atgctTCTGAGaaagtctt
 1
 CCUCAGAU m6b Disrupted 0.095000 0.152000 2.060000

Mutation Mutation ID Sample Name Cancer Type
chr15:g.32732084T>C COSN8589810 J74_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4485 tttGGCCGTTgcaatctgc
 1
 UAACGGCC m7b (m7b->m6b) -0.265000 no TS 8.460000
hsa-miR-891a tttggcCGTTGCAatctgc
 0 UGCAACGA m7a Disrupted -0.154000 no TS 3.270000

Mutation Mutation ID Sample Name Cancer Type
chr15:g.32733343G>T COSN8589811 522_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1304-3p ccacacCAGTGAGgaaaaa
 3
 UCUCACUG m7b Created -0.011000 0.015000 -0.010000
hsa-miR-4292 ccacaCCAGGGaggaaaaa
 1
 CCCCUGGG m6b Disrupted -0.032000 no TS 3.970000
hsa-miR-4691-5p ccacaccagGGAGGAaaaa
 9
 GUCCUCCA m6b Disrupted -0.154000 -0.111000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr15:g.32734231A>G COSN6270713 RK201_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-137 tctaaAGCAATAttaagaa
 0 UUAUUGCU m7b Disrupted -0.211000 no TS -0.970000
hsa-miR-200b-3p tctaaagCAGTATTAagaa
 1
 UAAUACUG m8a Created 0.031000 -0.152000 -0.100000
hsa-miR-200c-3p tctaaagCAGTATTAagaa
 1
 UAAUACUG m8a Created 0.031000 -0.152000 -0.010000
hsa-miR-374c-5p tctaaagcaGTATTAagaa
 8
 AUAAUACA m6b Created -0.042000 -0.039000 -0.010000
hsa-miR-429 tctaaagCAGTATTAagaa
 1
 UAAUACUG m8a Created 0.031000 -0.142000 -0.020000
hsa-miR-655 tctaaagcaGTATTAagaa
 8
 AUAAUACA m6b Created 0.024000 0.027000 -0.060000

Mutation Mutation ID Sample Name Cancer Type
chr15:g.32734622T>C COSN8589812 J46_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4999-5p tgttctATACAGCctttgc
 0 UGCUGUAU m7b Created no TS -0.233000 -0.020000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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