SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_012201 |
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Gene Symbol: | GLG1 |
Description: | Homo sapiens golgi glycoprotein 1 (GLG1), transcript variant 2, mRNA. |
Gene Location: | chr16(-):74481325-74641042 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr16:g.74449390T>A | COSN407725 | TCGA-BH-A0HN-01 | [breast][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4511 |
agaagattcAGTTCTTatg |
0 | GAAGAACU | m7b | (m6b->m7b) | 0.103000 | 0.152000 | No effect | |
hsa-miR-4773 |
agaagattCTGTTCTtatg |
0 | CAGAACAG | m7b | Disrupted | -0.077000 | -0.102000 |
0.250000 |
|
hsa-miR-5187-3p |
agaaGATTCAGTtcttatg |
0 | ACUGAAUC | m8a | Created | no TS | 0.006000 |
-0.030000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr16:g.74449752G>A | COSN4767227 | tumor_4142267 | [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-376c |
tgcagtTCTATGTTagtgc |
15 |
AACAUAGA | m8a | Created | -0.344000 | -0.258000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr16:g.74451560C>G | 9_136254 | CRC-1-Tumor | Colorectal adenocarcinoma | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-2467-3p |
cactcttgCCTCTGCTctg |
5 |
AGCAGAGG | m8a | Disrupted | -0.231 | -0.108 |
0.03 |
|
hsa-miR-31-5p |
cacTCTTGCCTctgctctg |
3 |
AGGCAAGA | m8a | Disrupted | -0.107 | -0.043 |
4.68 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr16:g.74451824C>T | COSN522274 | TCGA-A2-A0EV-01 | [breast][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1827 |
tggccatcCTGCCTCAttc |
2 |
UGAGGCAG | m8a | Created | -0.103000 | -0.432000 | No effect | |
hsa-miR-2392 |
tggCCATCCTgcctcattc |
1 |
UAGGAUGG | m7b | (m6c->m7b) | 0.070000 | -0.070000 | No effect | |
hsa-miR-3197 |
tggccatccCGCCTCattc |
1 |
GGAGGCGC | m6b | Disrupted | -0.290000 | -0.068000 | No effect | |
hsa-miR-940 |
tggccatCCTGCCTcattc |
0 | AAGGCAGG | m7b | Created | 0.030000 | -0.177000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr16:g.74451922G>T | COSN1190544 | BN03T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1225-5p |
ttgctgcgtGTACCCACtc |
6 |
GUGGGUAC | m8a | (m8a->m7a) | -0.249000 | no TS |
0.220000 |
hsa-miR-555 |
ttgctgcgtTTACCCactc |
0 | AGGGUAAG | m6b | Created | no TS | -0.110000 |
-0.050000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
74449389 | rs11149721 | C | G |
hsa-miR-4511 hsa-miR-4773 hsa-miR-548b-3p |
0 |
gattctGTTCTTA gattCTGTTCTta gattctGTTCTTA |
Created Created Created |
N N N |
0.103 0.025 0.094 |
C |
hsa-miR-3123 hsa-miR-3653 hsa-miR-5197-3p |
0 |
gATTCTCTtctta gattctCTTCTTA gattCTCTTCTta |
Disrupted Disrupted Disrupted |
N N N |
0.124 0.108 0.018 |
|||
74449390 | rs75534023 | T | T |
hsa-miR-4773 |
0 |
agattCTGTTCTt |
Disrupted |
N |
0.025 |
A |
hsa-miR-4511 hsa-miR-5187-3p |
0 |
agattcAGTTCTT aGATTCAGttctt |
Created Created |
N N |
0.049 0.006 |
|||
74450231 | rs111483912 | G | G |
hsa-miR-1972 |
3 |
gactcTGGCCTGt |
Disrupted |
N |
0.002 |
T |
hsa-miR-31-5p hsa-miR-4742-5p |
3 3 |
gacTCTTGCCtgt gactcTTGCCTGt |
Created Created |
N N |
0.029 0.048 |
|||
74450946 | rs181743464 | T | T |
hsa-miR-3133 hsa-miR-4773 |
6 4 |
tttctGTTCTTTc tttCTGTTCTttc |
Disrupted Disrupted |
N N |
0.011 -0.102 |
A |
hsa-miR-2115-3p hsa-miR-383-5p |
5 4 |
tTTCTGATctttc ttTCTGATCtttc |
Created Created |
N N |
-0.035 -0.138 |
|||
74451824 | rs3851730 | C | C |
hsa-miR-3197 hsa-miR-6087 hsa-miR-6765-5p |
1 1 1 |
ccatccCGCCTCA ccatcCCGCCTCA ccatccCGCCTCA |
Disrupted Disrupted Disrupted |
N N N |
-0.222 -0.481 -0.216 |
T |
hsa-miR-1827 hsa-miR-2392 hsa-miR-6808-5p hsa-miR-6893-5p hsa-miR-940 |
1 2 1 1 1 |
ccatcCTGCCTCA CCATCCTgcctca ccatCCTGCCTca ccatCCTGCCTca ccatCCTGCCTca |
Created Created Created Created Created |
N N N N N |
-0.329 -0.14 -0.217 -0.207 -0.207 |