SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_001145666
Gene Symbol:	GLG1
Description:	Homo sapiens golgi glycoprotein 1 (GLG1), transcript variant 2, mRNA.
Gene Location:	chr16(-):74481325-74641042
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr16:g.74449390T>A			COSN407725		TCGA-BH-A0HN-01		[breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4511	agaagattcAGTTCTTatg	0	GAAGAACU	m7b	(m6b->m7b)	0.103000	0.152000	No effect
hsa-miR-4773	agaagattCTGTTCTtatg	0	CAGAACAG	m7b	Disrupted	-0.077000	-0.102000	0.250000
hsa-miR-5187-3p	agaaGATTCAGTtcttatg	0	ACUGAAUC	m8a	Created	no TS	0.006000	-0.030000

Mutation			Mutation ID		Sample Name		Cancer Type
chr16:g.74449752G>A			COSN4767227		tumor_4142267		[haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-376c	tgcagtTCTATGTTagtgc	15	AACAUAGA	m8a	Created	-0.344000	-0.258000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr16:g.74451560C>G			9_136254		CRC-1-Tumor		Colorectal adenocarcinoma
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-2467-3p	cactcttgCCTCTGCTctg	5	AGCAGAGG	m8a	Disrupted	-0.231	-0.108	0.03
hsa-miR-31-5p	cacTCTTGCCTctgctctg	3	AGGCAAGA	m8a	Disrupted	-0.107	-0.043	4.68

Mutation			Mutation ID		Sample Name		Cancer Type
chr16:g.74451824C>T			COSN522274		TCGA-A2-A0EV-01		[breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1827	tggccatcCTGCCTCAttc	2	UGAGGCAG	m8a	Created	-0.103000	-0.432000	No effect
hsa-miR-2392	tggCCATCCTgcctcattc	1	UAGGAUGG	m7b	(m6c->m7b)	0.070000	-0.070000	No effect
hsa-miR-3197	tggccatccCGCCTCattc	1	GGAGGCGC	m6b	Disrupted	-0.290000	-0.068000	No effect
hsa-miR-940	tggccatCCTGCCTcattc	0	AAGGCAGG	m7b	Created	0.030000	-0.177000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr16:g.74451922G>T			COSN1190544		BN03T		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1225-5p	ttgctgcgtGTACCCACtc	6	GUGGGUAC	m8a	(m8a->m7a)	-0.249000	no TS	0.220000
hsa-miR-555	ttgctgcgtTTACCCactc	0	AGGGUAAG	m6b	Created	no TS	-0.110000	-0.050000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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