SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_000821
Gene Symbol: GGCX
Description: Homo sapiens gamma-glutamyl carboxylase (GGCX), transcript variant 1, mRNA.
Gene Location: chr2(-):85771977-85788657
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr2:g.85545408T>C COSN1861378 RK035_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr2:g.85545962A>T 9_83516 CRC-8-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4668-3p ggtctgcGGATTTTCtaca
 5
 GAAAAUCC m8a Disrupted 0.159 no TS 0.05
hsa-miR-548ac ggtctgcGGTTTTTctaca
 6
 CAAAAACC m7b Created 0.25 0.396 -0.55
hsa-miR-548at-3p ggtctgCGGTTTTtctaca
 2
 CAAAACCG m7b Created 0.043 0.071 -2.42
hsa-miR-548d-3p ggtctgcGGTTTTTctaca
 6
 CAAAAACC m7b Created 0.294 0.449 -1.12
hsa-miR-548h-3p ggtctgcGGTTTTTctaca
 6
 CAAAAACC m7b Created 0.274 0.42 -3.52
hsa-miR-548z ggtctgcGGTTTTTctaca
 6
 CAAAAACC m7b Created 0.274 0.42 -3.52

Mutation Mutation ID Sample Name Cancer Type
chr2:g.85547491A>G COSN5961751 RK149_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2110 cccTTCCCCAAactgttag
 1
 UUGGGGAA m8a Disrupted 0.034000 -0.010000 No effect
hsa-miR-3150a-3p ccctTCCCCAaactgttag
 1
 CUGGGGAG m6b Disrupted 0.006000 -0.009000 No effect
hsa-miR-4260 cccttCCCCAAactgttag
 2
 CUUGGGGC m6b Disrupted -0.320000 -0.330000 No effect
hsa-miR-450a-3p ccctTCCCCAAactgttag
 2
 AUUGGGGA m7b Disrupted -0.166000 -0.141000 -0.070000
hsa-miR-4725-3p ccCTTCCCCAaactgttag
 1
 UGGGGAAG m8a (m8a->m7b) -0.017000 0.022000 -0.140000
hsa-miR-542-5p ccctTCCCCGAactgttag
 0 UCGGGGAU m7a Created no TS -0.094000 -0.020000
hsa-miR-5572 cccttCCCCAAactgttag
 2
 GUUGGGGU m6b Disrupted -0.113000 -0.116000 0.020000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.85547620T>G COSN14599451 8014964 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-196a-3p agaagatacGTTGCCacta
 0 CGGCAACA m6b Created no TS -0.024000 -5.180000
hsa-miR-3973 agaagaTACTTTGccacta
 1
 ACAAAGUA m7b Disrupted 0.179000 0.101000 0.010000
hsa-miR-548l agaagATACTTTgccacta
 2
 AAAAGUAU m7b Disrupted 0.529000 0.353000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.85548341A>C COSN10009473 C0051T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5590-3p ttattCTTTATTattgaat
 0 AAUAAAGU m7a Disrupted NA NA 0.020000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.85549048A>T COSN1861380 RK027_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5010-3p atgcACACAAAgtaattta
 1
 UUUUGUGU m7b Disrupted -0.023000 no TS No effect
hsa-miR-599 atgcACACAAagtaattta
 1
 GUUGUGUC m6b Disrupted -0.016000 no TS No effect
hsa-miR-5010-3p atgcACACAAAgtaattta
 1
 UUUUGUGU m7b Disrupted -0.023000 no TS No effect
hsa-miR-599 atgcACACAAagtaattta
 1
 GUUGUGUC m6b Disrupted -0.016000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.85549140A>G COSN8896985 SS6003109 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-145-3p gtaattttcGGAATCactg
 15
 GGAUUCCU m6b Created -0.390000 -0.467000 -0.020000
hsa-miR-4766-5p gtaatTTTCAGAatcactg
 0 UCUGAAAG m7a Disrupted 0.068000 0.053000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.85549782C>T COSN15229202 LP6005334-DNA_E03 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-382-5p agattACAACTTagaggaa
 0 GAAGUUGU m7b Disrupted -0.271000 no TS 0.540000
hsa-miR-4799-5p agattacaATTTAGAggaa
 0 AUCUAAAU m7b Created 0.032000 -0.028000 -3.050000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.85549918G>A COSN1861382 RK141_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-500a-3p ccagatgttAGGTGCAgat
 0 AUGCACCU m7b (m6b->m7b) no TS -0.260000 -1.040000
hsa-miR-500a-3p ccagatgttAGGTGCAgat
 0 AUGCACCU m7b (m6b->m7b) no TS -0.260000 -1.040000
hsa-miR-500a-3p ccagatgttAGGTGCAgat
 0 AUGCACCU m7b (m6b->m7b) no TS -0.26 -1.04

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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