SomamiR DB

SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only All 6mer or longer seed matches

PolymiRTS Database

RefSeq ID:	NM_000144
Gene Symbol:	FXN
Description:	Homo sapiens frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA.
Gene Location:	chr9(+):71650478-71693993

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69072810C>T			COSN14953500		LP6005409-DNA_E01		[oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1182	ccaAGACCCTagcttcatt	4	GAGGGUCU	m7b	(m6b->m7b)	0.041000	-0.384000	-0.010000
hsa-miR-320e	ccaagaccCCAGCTTcatt	6	AAAGCUGG	m7b	Disrupted	-0.150000	no TS	No effect
hsa-miR-4731-5p	ccaagaCCCCAGCttcatt	2	UGCUGGGG	m7b	Disrupted	-0.636000	-0.335000	No effect
hsa-miR-615-5p	ccaaGACCCCagcttcatt	5	GGGGGUCC	m6b	Disrupted	-0.231000	-0.024000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69072811A>G			COSN14972511		LP6005409-DNA_E01		[oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-127-5p	caagaccccAGCTTCAtta	3	CUGAAGCU	m7b	(m7b->m6c)	-0.152000	no TS	-0.060000
hsa-miR-320e	caagaccCCAGCTTcatta	6	AAAGCUGG	m7b	Disrupted	-0.150000	no TS	No effect
hsa-miR-4731-5p	caagaCCCCAGCttcatta	2	UGCUGGGG	m7b	Disrupted	-0.636000	-0.335000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69072854G>T			COSN2325426		RK022_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3529-3p	gttgTTGTTGTTtattttt	0	AACAACAA	m8a	Disrupted	-0.594000	-0.483000	No effect
hsa-miR-3529-3p	gttgTTGTTGTTtattttt	0	AACAACAA	m8a	Disrupted	-0.594	-0.483	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69073008C>T			COSN14740921		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-144-5p	cacaTGATATCCcttatct	0	GGAUAUCA	m8a	Created	no TS	-0.128000	-0.010000
hsa-miR-3936	cacatgatACCCCTTAtct	0	UAAGGGGU	m8a	Disrupted	-0.438000	no TS	No effect
hsa-miR-4475	cacatgataTCCCTTatct	2	CAAGGGAC	m6b	Created	-0.179000	-0.334000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69073185A>G			COSN14834261		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1270	cactgttctATCTCCAaat	1	CUGGAGAU	m7b	(m7b->m6c)	-0.277000	-0.101000	0.090000
hsa-miR-3676-5p	cactgttctATCTCCaaat	1	AGGAGAUC	m6b	Disrupted	-0.131000	-0.026000	No effect
hsa-miR-4524a-3p	cactgttCTGTCTCcaaat	1	UGAGACAG	m7b	Created	-0.112000	-0.261000	-0.100000
hsa-miR-4683	cactgttctATCTCCAaat	1	UGGAGAUC	m7a	(m7a->m6b)	-0.137000	-0.029000	0.430000
hsa-miR-4773	caCTGTTCTGtctccaaat	0	CAGAACAG	m8a	(m7a->m8a)	-0.208000	-0.096000	0.860000
hsa-miR-589-3p	cacTGTTCTGtctccaaat	1	UCAGAACA	m7b	(m6b->m7b)	-0.080000	-0.153000	-2.450000
hsa-miR-620	cactgttctATCTCCAaat	1	AUGGAGAU	m7b	(m7b->m6c)	-0.256000	-0.094000	1.600000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69073302T>C			COSN14768778		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-141-5p	acgGGAAGATcatttctta	0	CAUCUUCC	m7b	(m7b->m6b)	-0.317000	-0.227000	No effect
hsa-miR-224-3p	acgggaagACCATTTctta	1	AAAAUGGU	m7b	Created	0.267000	0.231000	-0.020000
hsa-miR-522-3p	acgggaagACCATTTctta	1	AAAAUGGU	m7b	Created	0.277000	0.260000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69073942T>G			ICGC_80DE34D6-2A78-11E2-96E7-04FD496BB9B8		CPCG_0102_Pr_P_P1		ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-106a-5p	caGCACTTTTggaggccaa	0	AAAAGUGC	m8a	(m8a->m7a)	0.311	0.338	0.01
hsa-miR-150-5p	cagcactTTGGGAGgccaa	0	UCUCCCAA	m7b	Created	0.16	0.205	No effect
hsa-miR-17-5p	caGCACTTTGggaggccaa	0	CAAAGUGC	m8a	(m7a->m8a)	0.311	0.338	0.01
hsa-miR-186-3p	cagcaCTTTGGGaggccaa	0	GCCCAAAG	m7b	Created	0.112	0.156	0.04
hsa-miR-20b-5p	caGCACTTTGggaggccaa	0	CAAAGUGC	m8a	(m7a->m8a)	0.332	0.359	0.04
hsa-miR-519d	caGCACTTTGggaggccaa	0	CAAAGUGC	m8a	(m7a->m8a)	0.353	0.38	No effect
hsa-miR-520g	cagCACTTTGggaggccaa	0	ACAAAGUG	m7b	(m6b->m7b)	0.363	0.512	No effect
hsa-miR-520h	cagCACTTTGggaggccaa	0	ACAAAGUG	m7b	(m6b->m7b)	0.363	0.512	No effect
hsa-miR-548t-5p	cagCACTTTTGgaggccaa	2	CAAAAGUG	m8a	Disrupted	0.18	no TS	No effect
hsa-miR-93-5p	caGCACTTTGggaggccaa	0	CAAAGUGC	m8a	(m7a->m8a)	0.353	0.38	0.27

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69074037T>G			COSN9284284		C0017T		[kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4735-5p	acaaaAAATTAGccgggca	1	CCUAAUUU	m7b	Disrupted	0.307000	0.156000	0.060000
hsa-miR-4775	acaaAAAATTAgccgggca	1	UUAAUUUU	m7b	Disrupted	0.528000	0.315000	2.220000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69074049A>G			ICGC_DD0A0B7C-2A78-11E2-B303-24FD496BB9B8		CPCG_0103_Pr_P_P6		ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4715-3p	ccgggcatGGTGGCAggtg	0	GUGCCACC	m7b	Created	no TS	-0.057	-0.03
hsa-miR-4769-3p	ccgggcatgATGGCAGgtg	0	UCUGCCAU	m7b	(m7b->m6c)	0.108	0.091	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69074077T>C			COSN14764625		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-150-5p	ccagctacTTGGGAGgctg	2	UCUCCCAA	m7b	Disrupted	0.160000	0.090000	No effect
hsa-miR-4740-3p	ccagctaCTCGGGaggctg	2	GCCCGAGA	m6b	Created	-0.052000	-0.102000	-0.010000
hsa-miR-562	ccaGCTACTTgggaggctg	0	AAAGUAGC	m7b	(m7b->m6b)	0.059000	no TS	No effect
hsa-miR-5697	ccagCTACTTGggaggctg	1	UCAAGUAG	m7b	Disrupted	0.154000	0.043000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69074088A>G			COSN14767006		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-572	ggaggctgaAGCGGAagaa	0	GUCCGCUC	m6b	Disrupted	-0.090000	no TS	0.040000
hsa-miR-718	ggaggctgaGGCGGAAGaa	0	CUUCCGCC	m8a	(m7b->m8a)	no TS	-0.130000	-0.090000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69074129A>G			COSN14870679		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1273g-3p	gttGCAGTGGgccgagatc	2	ACCACUGC	m7b	(m6b->m7b)	-0.147000	-0.166000	No effect
hsa-miR-1304-3p	gttgCAGTGAGccgagatc	2	UCUCACUG	m7b	Disrupted	0.258000	0.189000	No effect
hsa-miR-4284	gttgcaGTGAGCCgagatc	2	GGGCUCAC	m7b	Disrupted	-0.045000	-0.021000	No effect
hsa-miR-4638-5p	gttgcagtgAGCCGAGatc	1	ACUCGGCU	m7b	(m7b->m6c)	-0.295000	-0.242000	No effect
hsa-miR-4665-3p	gttgcagtgGGCCGAGatc	0	CUCGGCCG	m7a	(m6b->m7a)	NA	NA	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69074459A>G			COSN14768149		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4532	cttgaCCCCGGGcggagga	0	CCCCGGGG	m7b	Created	no TS	-0.101000	No effect
hsa-miR-661	cttgacCCCAGGCggagga	1	UGCCUGGG	m7b	Disrupted	-0.049000	-0.072000	-0.110000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69074499G>A			COSN14705655		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1267	tacctgagCAACAGagcga	2	CCUGUUGA	m6b	Created	0.097000	0.168000	-1.470000
hsa-miR-367-5p	tacctgaGCAACAGagcga	2	ACUGUUGC	m7b	Created	0.090000	0.125000	-0.710000
hsa-miR-744-3p	tacctgaGCAACAGagcga	2	CUGUUGCC	m7a	Created	0.068000	0.068000	-4.380000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69074549G>A			COSN14780373		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4477a	tttaTTAATAagaagtttg	2	CUAUUAAG	m6b	Created	0.138000	0.310000	-0.060000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69074639C>A			COSN15616143		C0080T		[kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-101-5p	tggcatATAACTatagtcc	2	CAGUUAUC	m6b	Created	0.027000	0.134000	-0.020000
hsa-miR-331-5p	tggcatATACCTAtagtcc	2	CUAGGUAU	m7b	Disrupted	0.027000	no TS	No effect
hsa-miR-4678	tggcatATACCTatagtcc	2	AAGGUAUU	m6b	Disrupted	0.064000	no TS	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69074670C>T			COSN9284478		C0075T		[kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1285-5p	aggcTGAGATaggaggatt	0	GAUCUCAC	m6b	Created	no TS	0.093000	-0.140000
hsa-miR-1976	aggctgagaCAGGAGGatt	2	CCUCCUGC	m7a	(m7a->m6b)	-0.272000	-0.272000	No effect
hsa-miR-3120-5p	aggctgAGACAGGaggatt	2	CCUGUCUG	m7a	Disrupted	0.095000	0.095000	No effect
hsa-miR-4421	aggctgAGACAGGaggatt	1	ACCUGUCU	m7b	Disrupted	0.031000	-0.051000	No effect
hsa-miR-5699	aggctgAGACAGGAggatt	1	UCCUGUCU	m8a	Disrupted	0.041000	-0.009000	No effect
hsa-miR-660-3p	aggctgagaCAGGAGGatt	2	ACCUCCUG	m7b	(m7b->m6c)	-0.226000	-0.186000	0.070000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69074717C>T			COSN14757256		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-31-3p	tgggcaaCATAGCAagatc	2	UGCUAUGC	m7a	Created	-0.220000	-0.201000	No effect
hsa-miR-4781-3p	tgggCAACATagcaagatc	2	AAUGUUGG	m6b	Created	0.204000	0.319000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69074840T>C			COSN14749861		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-543	tgatggaAATGTTTaagtg	0	AAACAUUC	m7a	Disrupted	NA	NA	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69074964G>A			COSN14745742		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-323a-3p	cggtgacaTAATGTactcc	0	CACAUUAC	m6b	Created	no TS	0.143000	-1.600000
hsa-miR-499a-3p	cggtgacaTGATGTactcc	1	AACAUCAC	m6b	Disrupted	-0.043000	-0.133000	1.920000
hsa-miR-499b-3p	cggtgacaTGATGTactcc	1	AACAUCAC	m6b	Disrupted	-0.043000	-0.133000	0.020000
hsa-miR-96-3p	cggtgACATGATgtactcc	2	AAUCAUGU	m7b	Disrupted	-0.027000	-0.138000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69075266T>C			COSN14686266		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4435	agaccagcCTGGCCAacat	1	AUGGCCAG	m7b	Disrupted	-0.057000	-0.062000	No effect
hsa-miR-4492	agaCCAGCCCggccaacat	4	GGGGCUGG	m7b	(m6b->m7b)	0.018000	-0.036000	No effect
hsa-miR-4498	agaCCAGCCCggccaacat	4	UGGGCUGG	m7b	(m6b->m7b)	-0.120000	-0.109000	No effect
hsa-miR-4743	agaccagcCCGGCCAacat	0	UGGCCGGA	m7a	Created	no TS	-0.123000	No effect
hsa-miR-4755-3p	agaccaGCCTGGCcaacat	3	AGCCAGGC	m7b	Disrupted	-0.326000	-0.268000	No effect
hsa-miR-5001-5p	agaCCAGCCCggccaacat	4	AGGGCUGG	m7b	(m6b->m7b)	-0.036000	-0.027000	No effect
hsa-miR-548s	agaccagccTGGCCAacat	2	AUGGCCAA	m6b	Disrupted	-0.073000	-0.096000	No effect
hsa-miR-762	agaCCAGCCCggccaacat	4	GGGGCUGG	m7b	(m6b->m7b)	-0.036000	-0.027000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69075321G>A			COSN7809226		PCSI_0224_Pa_P_526		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69075330C>T			COSN14773090		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3622a-5p	gtggtggttCGTGCCTata	2	CAGGCACG	m7b	(m7b->m6c)	-0.155000	-0.059000	No effect
hsa-miR-497-3p	gtgGTGGTTTGtgcctata	1	CAAACCAC	m8a	Created	0.081000	0.213000	No effect
hsa-miR-5582-5p	gtggtggttTGTGCCTAta	2	UAGGCACA	m8a	(m7b->m8a)	-0.051000	-0.086000	No effect
hsa-miR-564	gtggtggttCGTGCCTata	2	AGGCACGG	m7a	(m7a->m6b)	-0.077000	-0.077000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69075759C>A			COSN2325427		RK075_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-144-5p	agacagGATATCactttgg	0	GGAUAUCA	m6b	Created	no TS	0.066000	-0.040000
hsa-miR-3689a-5p	agacaggATATCACtttgg	0	UGUGAUAU	m7b	Created	no TS	0.088000	-2.640000
hsa-miR-3689b-5p	agacaggATATCACtttgg	0	UGUGAUAU	m7b	Created	no TS	0.088000	-2.640000
hsa-miR-3689e	agacaggATATCACtttgg	0	UGUGAUAU	m7b	Created	no TS	0.088000	-2.640000
hsa-miR-3689f	agacaggATATCACtttgg	0	UGUGAUAU	m7b	Created	no TS	0.088000	-0.430000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69076047A>C			COSN14774953		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1182	gtgggtAGACCCTCagcca	4	GAGGGUCU	m8a	Created	0.041000	0.032000	No effect
hsa-miR-182-3p	gtgggTAGAACCtcagcca	0	UGGUUCUA	m7b	Disrupted	0.069000	no TS	0.010000
hsa-miR-377-5p	gtgggtagAACCTCagcca	1	AGAGGUUG	m6b	Disrupted	0.109000	0.065000	0.020000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69076058A>G			COSN14759280		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4474-3p	ctcAGCCACAtagaaaata	2	UUGUGGCU	m7b	(m7b->m6b)	-0.244000	-0.218000	No effect
hsa-miR-4482-3p	ctcagccacATAGAAAata	2	UUUCUAUU	m7a	(m7a->m6b)	0.218000	0.098000	No effect
hsa-miR-4491	ctcagCCACATagaaaata	0	AAUGUGGA	m6b	Disrupted	-0.066000	-0.077000	0.260000
hsa-miR-4657	ctcagCCACATagaaaata	0	AAUGUGGA	m6b	Disrupted	-0.073000	-0.077000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69076114G>C			COSN14790560		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-103a-2-5p	acaAAGAAGCaatgaggtg	0	AGCUUCUU	m7b	(m6b->m7b)	no TS	0.042000	-0.170000
hsa-miR-1237	acaaAGAAGGAatgaggtg	3	UCCUUCUG	m7a	Disrupted	-0.076000	-0.104000	No effect
hsa-miR-1248	acaAAGAAGGaatgaggtg	0	ACCUUCUU	m7b	(m7b->m6b)	-0.169000	-0.203000	0.040000
hsa-miR-3977	acaaaGAAGCAatgaggtg	0	GUGCUUCA	m6b	Created	no TS	-0.001000	-0.500000
hsa-miR-4317	acaaagaaGCAATGaggtg	0	ACAUUGCC	m6b	Created	no TS	0.026000	-0.200000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69076323G>A			COSN14894872		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4709-5p	atgacaACTGTTGTtctca	0	ACAACAGU	m8a	Disrupted	-0.011000	-0.024000	0.290000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69076471A>T			COSN9714158		AOCS-058-1-5		[ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-224-3p	gaACCATTTTtcgtgtgcc	1	AAAAUGGU	m8a	(m7a->m8a)	0.267000	0.211000	No effect
hsa-miR-522-3p	gaACCATTTTtcgtgtgcc	1	AAAAUGGU	m8a	(m7a->m8a)	0.277000	0.220000	0.030000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69077164C>G			COSN14740922		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-25-5p	acctgcCTCCGCCTcccaa	0	AGGCGGAG	m8a	Disrupted	-0.122000	-0.069000	0.010000
hsa-miR-3612	accTGCCTCCgcctcccaa	0	AGGAGGCA	m7b	(m7b->m6b)	-0.201000	-0.265000	0.150000
hsa-miR-650	accTGCCTCCgcctcccaa	0	AGGAGGCA	m7b	(m7b->m6b)	-0.229000	-0.311000	0.180000
hsa-miR-658	acctgCCTCCGCCtcccaa	0	GGCGGAGG	m8a	Disrupted	-0.200000	-0.135000	0.140000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69077221T>G			COSN14763873		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3154	agaaatgCCTTCTaatctt	0	CAGAAGGG	m6b	Disrupted	0.032000	0.008000	2.550000
hsa-miR-3910	agaaATGCCTTctaatctt	5	AAAGGCAU	m7b	Disrupted	0.048000	0.002000	No effect
hsa-miR-4493	agaaatGCCTTCTaatctt	0	AGAAGGCC	m7a	Disrupted	NA	NA	3.050000
hsa-miR-483-5p	agaaatgCCGTCTaatctt	0	AAGACGGG	m6b	Created	-0.219000	-0.281000	-0.030000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69077469A>G			COSN14744452		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4502	gaaaaCATCAGCacccagc	1	GCUGAUGA	m7a	Disrupted	-0.001000	-0.001000	0.010000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69077895A>T			COSN14835013		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-143-5p	caccACTGCACtccagcct	3	GGUGCAGU	m7b	Disrupted	-0.006000	-0.006000	No effect
hsa-miR-2278	caccaCTGCTCTCcagcct	1	GAGAGCAG	m8a	Created	0.074000	0.059000	No effect
hsa-miR-4519	cacCACTGCTctccagcct	0	CAGCAGUG	m7b	(m6b->m7b)	no TS	0.019000	No effect
hsa-miR-5192	caccactgCTCTCCagcct	0	AGGAGAGU	m6b	Created	no TS	0.008000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69077896C>G			COSN14780374		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1269a	accactgCAGTCCAGcctg	2	CUGGACUG	m8a	Created	-0.051000	-0.053000	No effect
hsa-miR-1269b	accactgCAGTCCAGcctg	2	CUGGACUG	m8a	Created	-0.060000	-0.043000	No effect
hsa-miR-1288	accactGCAGTCCAgcctg	2	UGGACUGC	m8a	Created	-0.085000	-0.248000	No effect
hsa-miR-143-5p	accACTGCACtccagcctg	3	GGUGCAGU	m7b	(m7b->m6b)	-0.006000	-0.006000	No effect
hsa-miR-17-3p	accACTGCAGTccagcctg	0	ACUGCAGU	m8a	Created	no TS	0.060000	No effect
hsa-miR-3135b	accactgcaCTCCAGCCtg	0	GGCUGGAG	m8a	(m8a->m7b)	-0.468000	-0.365000	No effect
hsa-miR-378a-3p	accactgcAGTCCAGcctg	1	ACUGGACU	m7b	Created	-0.064000	-0.039000	No effect
hsa-miR-378b	accactgcAGTCCAGcctg	1	ACUGGACU	m7b	Created	-0.071000	-0.036000	No effect
hsa-miR-378c	accactgcAGTCCAGcctg	1	ACUGGACU	m7b	Created	-0.064000	-0.039000	No effect
hsa-miR-378d	accactgcAGTCCAGcctg	1	ACUGGACU	m7b	Created	-0.064000	-0.039000	No effect
hsa-miR-378e	accactgcAGTCCAGcctg	1	ACUGGACU	m7b	Created	-0.064000	-0.039000	No effect
hsa-miR-378f	accactgcAGTCCAGcctg	1	ACUGGACU	m7b	Created	-0.064000	-0.020000	No effect
hsa-miR-378h	accactgcAGTCCAGcctg	1	ACUGGACU	m7b	Created	-0.064000	-0.048000	No effect
hsa-miR-378i	accactgcAGTCCAGcctg	1	ACUGGACU	m7b	Created	-0.064000	-0.039000	No effect
hsa-miR-422a	accactgcAGTCCAGcctg	1	ACUGGACU	m7b	Created	-0.064000	-0.039000	No effect
hsa-miR-4418	accaCTGCAGTccagcctg	2	CACUGCAG	m7b	Created	0.028000	0.082000	No effect
hsa-miR-4515	accactgCAGTCCagcctg	1	AGGACUGG	m6b	Created	-0.247000	-0.257000	No effect
hsa-miR-4740-5p	accactgCAGTCCagcctg	2	AGGACUGA	m6b	Created	-0.078000	-0.089000	No effect
hsa-miR-509-3-5p	accaCTGCAGTccagcctg	2	UACUGCAG	m7b	Created	0.028000	0.035000	No effect
hsa-miR-509-5p	accaCTGCAGTccagcctg	2	UACUGCAG	m7b	Created	0.031000	0.038000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69077908T>C			COSN14757257		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1295b-5p	cagcCTGGGTGacaagagg	0	CACCCAGA	m7a	Disrupted	NA	NA	-0.060000
hsa-miR-3655	cagcctgggCGACAAGagg	1	GCUUGUCG	m7b	(m6c->m7b)	-0.078000	-0.110000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69077930A>G			COSN14846664		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4263	actccaTTAGAAaaatgta	2	AUUCUAAG	m6b	Created	0.174000	0.284000	-0.020000
hsa-miR-576-5p	actccATTAGAAaaatgta	5	AUUCUAAU	m7b	Created	0.112000	0.279000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69077946G>A			COSN14904153		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4462	gtaattcCCGTGTCtgcca	2	UGACACGG	m7b	Disrupted	-0.251000	-0.118000	0.020000
hsa-miR-4681	gtaaTTCCCGTgtctgcca	1	AACGGGAA	m7b	Disrupted	-0.160000	no TS	0.230000
hsa-miR-602	gtaattCCCGTGTCtgcca	2	GACACGGG	m8a	Disrupted	-0.202000	no TS	3.240000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69078163C>G			COSN14686267		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3919	aggatTTCTCTGtaagatt	0	GCAGAGAA	m7b	Disrupted	0.102000	0.196000	No effect
hsa-miR-466	aggatttcTGTGTAagatt	1	AUACACAU	m6b	Created	0.200000	0.218000	-0.030000
hsa-miR-4672	aggatttCTGTGTAAgatt	2	UUACACAG	m8a	Created	0.197000	0.106000	0.460000
hsa-miR-4797-5p	aggatttCTCTGTaagatt	0	GACAGAGU	m6b	Disrupted	-0.145000	-0.119000	No effect
hsa-miR-539-5p	aggATTTCTCtgtaagatt	0	GGAGAAAU	m7b	(m7b->m6b)	0.071000	no TS	No effect
hsa-miR-600	aggatttctCTGTAAGatt	0	ACUUACAG	m7b	(m7b->m6c)	-0.091000	0.014000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69078376G>A			COSN14792362		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3144-5p	ctcctgcccGTCCCCagtg	0	AGGGGACC	m6b	Disrupted	-0.112000	no TS	1.580000
hsa-miR-3191-3p	ctcctgccCGTCCCCAgtg	0	UGGGGACG	m8a	Disrupted	-0.257000	no TS	1.340000
hsa-miR-4652-5p	ctcctgcccGTCCCCagtg	0	AGGGGACU	m6b	Disrupted	-0.103000	no TS	0.060000
hsa-miR-92b-5p	ctcctgcCCGTCCCcagtg	0	AGGGACGG	m7b	Disrupted	-0.165000	no TS	5.570000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69078565C>T			COSN14832991		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69078603T>C			COSN7809227		ASHPC_0005_Pa_P_1		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-297	ctctACATACAattatgct	0	AUGUAUGU	m7b	Created	no TS	-0.221000	-0.040000
hsa-miR-3149	ctctaCATACAAttatgct	2	UUUGUAUG	m7b	Created	0.307000	0.206000	-0.050000
hsa-miR-3924	ctcTACATATaattatgct	0	AUAUGUAU	m7a	(m7a->m6a)	NA	NA	No effect
hsa-miR-567	ctctACATACaattatgct	1	AGUAUGUU	m6b	Created	0.055000	0.001000	-0.010000
hsa-miR-675-3p	ctctaCATACAattatgct	0	CUGUAUGC	m6b	Created	no TS	-0.070000	No effect
hsa-miR-944	ctctacatATAATTatgct	1	AAAUUAUU	m6b	Disrupted	0.076000	-0.011000	0.480000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.69078861C>T			COSN14765253		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

**Germline mutations in target sites of miRNAs in somatic mutation table**
Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
69072840	rs146039377	-	TTG	hsa-miR-3065-5p hsa-miR-3529-3p hsa-miR-3613-3p	0	tctgtttTTTGTTGttg tctgttttTTGTTGTtg tctgTTTTTTGttgttg	Unknown Unknown Unknown	N N N	0.005 -0.125 0.001
69072840	rs146039377	-	-
69072842	rs35195101	-	GTT	hsa-miR-3065-5p hsa-miR-3529-3p hsa-miR-3613-3p	0	tgtttTTTGTTGttgtt tgttttTTGTTGTtgtt tgTTTTTTGttgttgtt	Unknown Unknown Unknown	N N N	0.005 -0.125 0.001
69072842	rs35195101	-	-
69073008	rs10890	T	C	hsa-miR-3936	0	atgatACCCCTTA	Created	N	-0.438
69073008	rs10890	T	T	hsa-miR-144-5p hsa-miR-4475 hsa-miR-6892-5p	0	aTGATATCcctta atgataTCCCTTA atgataTCCCTTA	Disrupted Disrupted Disrupted	N N N	-0.128 -0.155 -0.244
69073185	rs4745577	G	A	hsa-miR-1270 hsa-miR-4683 hsa-miR-4773 hsa-miR-620	0	tgttctATCTCCA tgttctATCTCCA TGTTCTAtctcca tgttctATCTCCA	Created Created Created Created	LT N N LT	-0.176 -0.108 -0.112 -0.162
69073185	rs4745577	G	G	hsa-miR-139-3p hsa-miR-4524a-3p hsa-miR-589-3p	0	tgttctGTCTCCA tgttCTGTCTCca TGTTCTGtctcca	Disrupted Disrupted Disrupted	N N N	-0.143 -0.149 -0.073
69073302	rs4744806	C	T	hsa-miR-141-5p	1	GGAAGATcatttc	Created	N	-0.09
69073302	rs4744806	C	C	hsa-miR-224-3p hsa-miR-522-3p	1 1	ggaagACCATTTc ggaagACCATTTc	Disrupted Disrupted	N LT	-0.036 -0.017
69073318	rs7857635	C	C	hsa-miR-6501-3p	1	tttgTGCTCTGtg	Disrupted	N	-0.091
69073318	rs7857635	C	T	hsa-miR-589-3p	1	tttgTGTTCTGtg	Created	N	-0.052
69073384	rs4744807	A	A	hsa-miR-1233-5p hsa-miR-299-3p hsa-miR-4491 hsa-miR-4648 hsa-miR-4654 hsa-miR-4657 hsa-miR-4769-5p hsa-miR-6778-5p	1 1 2 1 1 2 1 1	TCCCACAtattca tCCCACATAttca tcCCACATAttca TCCCACAtattca TCCCACAtattca tcCCACATAttca TCCCACAtattca TCCCACAtattca	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N LT N N N N N N	-0.157 -0.318 -0.077 -0.148 -0.151 -0.077 -0.148 -0.156
69073384	rs4744807	A	G	hsa-miR-6082	2	tcccACGTATTca	Created	N	-0.058
69073560	rs11145043	T	T	hsa-miR-124-3p hsa-miR-506-3p hsa-miR-624-3p	1 1 1	gGTGCCTTgtaaa gGTGCCTTgtaaa ggtgCCTTGTAaa	Disrupted Disrupted Disrupted	LT LT LT	-0.05 -0.068 -0.037
69073560	rs11145043	T	G	hsa-miR-602	1	ggtgCCGTGTAaa	Created	N	-0.146
69073637	rs78598719	G	G	hsa-miR-4474-3p hsa-miR-4539 hsa-miR-7108-5p	1 1 2	agttcAGCCACAA AGTTCAGccacaa agttcaGCCACAA	Disrupted Disrupted Disrupted	N N N	-0.218 -0.045 -0.081
69073637	rs78598719	G	T	hsa-miR-1255a hsa-miR-1255b-5p hsa-miR-3691-5p hsa-miR-376b-5p hsa-miR-376c-5p hsa-miR-4752 hsa-miR-6744-5p hsa-miR-6833-5p hsa-miR-8056	1 1 1 1 1 7 1 2 1	agtTCATCCAcaa agtTCATCCAcaa agttCATCCACAa agttcATCCACAa agttcATCCACAa agttcATCCACAA agtTCATCCAcaa agttcaTCCACAA agttcATCCACAa	Created Created Created Created Created Created Created Created Created	N N N N N N N N N	-0.039 -0.039 -0.229 -0.089 -0.089 -0.149 -0.055 -0.044 -0.08
69073909	rs183393884	C	C	hsa-miR-4755-3p	1	GCCTGGCgcggtg	Disrupted	N	-0.066
69073909	rs183393884	C	T	hsa-miR-1911-3p hsa-miR-4733-3p	1 1	GCCTGGTgcggtg gCCTGGTGcggtg	Created Created	N N	-0.06 0.008
69073910	rs17847101	G
69073910	rs17847101	G	A	hsa-miR-4755-3p hsa-miR-5006-5p	1 1	CCTGGCAcggtgg CCTGGCAcggtgg	Created Created	N N	-0.111 -0.028
69074042	rs17847102	G
69074042	rs17847102	G	A	hsa-miR-1254 hsa-miR-3116 hsa-miR-4794 hsa-miR-661 hsa-miR-664a-5p	1 1 1 1 1	ttagCCAGGCAtg ttagCCAGGCAtg tTAGCCAGgcatg ttagCCAGGCAtg tTAGCCAGgcatg	Created Created Created Created Created	N N N N N	-0.075 -0.082 -0.028 -0.057 -0.056
69074077	rs4745578	C	T	hsa-miR-150-5p hsa-miR-562 hsa-miR-5697 hsa-miR-6814-5p	0	gctacTTGGGAGg GCTACTTgggagg gCTACTTGggagg gctaCTTGGGAgg	Created Created Created Created	N N N N	0.07 0.059 0.111 0.035
69074077	rs4745578	C	C	hsa-miR-4740-3p	0	gctaCTCGGGAgg	Disrupted	N	-0.05
69074088	rs4744810	G	A	hsa-miR-3157-5p hsa-miR-572	0	GGCTGAAgcggaa ggctgaAGCGGAA	Created Created	N N	0.004 -0.09
69074088	rs4744810	G	G	hsa-miR-6084 hsa-miR-718	0	ggctgaGGCGGAA ggctgaGGCGGAA	Disrupted Disrupted	N N	-0.116 -0.13
69074129	rs2871218	A	A	hsa-miR-1304-3p hsa-miR-4284 hsa-miR-4638-5p hsa-miR-6741-3p hsa-miR-6890-3p	1 1 1 1 1	gCAGTGAGccgag gcaGTGAGCCgag gcagtgAGCCGAG gcagtGAGCCGAg GCAGTGAgccgag	Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N	0.069 -0.024 -0.053 -0.069 0.04
69074129	rs2871218	A	G	hsa-miR-1273g-3p hsa-miR-6075	1 1	GCAGTGGgccgag gcagTGGGCCGAg	Created Created	N N	-0.019 -0.233
69074295	rs11145047	T	T	hsa-miR-106a-5p hsa-miR-106b-5p hsa-miR-142-5p hsa-miR-17-5p hsa-miR-20a-5p hsa-miR-20b-5p hsa-miR-340-5p hsa-miR-3609 hsa-miR-4796-3p hsa-miR-519d-3p hsa-miR-526b-3p hsa-miR-548ah-5p hsa-miR-5590-3p hsa-miR-568 hsa-miR-93-5p	2 2 2 2 2 2 3 2 2 2 2 2 2 8 2	GCACTTTAtacaa GCACTTTAtacaa gcACTTTATAcaa GCACTTTAtacaa GCACTTTAtacaa GCACTTTAtacaa gcaCTTTATAcaa gCACTTTAtacaa gCACTTTAtacaa GCACTTTAtacaa GCACTTTAtacaa gCACTTTAtacaa gcACTTTATAcaa gcactTTATACAA GCACTTTAtacaa	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N N N N N N N N N N	0.027 0.027 0.261 0.027 0.038 0.038 0.164 0.082 0.075 0.069 0.069 0.082 0.261 0.178 0.059
69074295	rs11145047	T	G	hsa-miR-6513-3p	2	gCACTTGAtacaa	Created	N	0.038
69074439	rs116944579	C	C	hsa-miR-1247-5p hsa-miR-340-3p hsa-miR-6827-3p	2 2 2	ctgaGACGGGAga ctGAGACGGgaga ctGAGACGGgaga	Disrupted Disrupted Disrupted	N N N	-0.07 -0.03 -0.04
69074439	rs116944579	C	T	hsa-miR-150-5p hsa-miR-2116-3p hsa-miR-4713-5p hsa-miR-532-3p	2 2 2 2	ctgagaTGGGAGA ctgagATGGGAGA ctgagaTGGGAGA ctgagaTGGGAGA	Created Created Created Created	N N N N	0.042 0.043 -0.035 0.025
69074459	rs1984004	G	A	hsa-miR-615-5p hsa-miR-661 hsa-miR-6852-5p hsa-miR-7155-5p hsa-miR-7704	0	GACCCCAggcgga gacCCCAGGCgga gaCCCCAGGcgga gACCCCAGgcgga GACCCCAggcgga	Created Created Created Created Created	N N N N N	-0.024 0.023 -0.004 0.054 -0.031
69074459	rs1984004	G	G	hsa-miR-4532	0	gaCCCCGGGcgga	Disrupted	N	-0.101
69074499	rs1888334	G
69074499	rs1888334	G	A	hsa-miR-1178-3p hsa-miR-1267 hsa-miR-367-5p hsa-miR-3934-3p	2 1 1 2	cTGAGCAAcagag ctgagCAACAGAg ctgaGCAACAGAg CTGAGCAacagag	Created Created Created Created	N N N N	0.039 0.071 0.035 -0.051
69074549	rs1984003	G	G	hsa-miR-6758-3p	1	attAATGAGAagt	Disrupted	N	0.053
69074549	rs1984003	G	A	hsa-miR-4477a	1	aTTAATAAgaagt	Created	N	0.172
69074717	rs1984002	T
69074717	rs1984002	T	T	hsa-miR-31-3p hsa-miR-4781-3p	0	gcaaCATAGCAag gCAACATAgcaag	Disrupted Disrupted	N N	0.019 0.115
69074964	rs4745581	G	G	hsa-miR-499a-3p hsa-miR-499b-3p hsa-miR-96-3p	1 1 1	tgacaTGATGTAc tgacaTGATGTAc tgACATGATgtac	Disrupted Disrupted Disrupted	N N N	0.09 0.09 0.111
69074964	rs4745581	G	A	hsa-miR-323a-3p	1	tgacaTAATGTAc	Created	N	0.143
69075266	rs4745583	T	T	hsa-miR-3187-3p hsa-miR-4435 hsa-miR-4701-5p hsa-miR-4755-3p hsa-miR-548s hsa-miR-588	2 2 2 2 2 2	ccagccTGGCCAA ccagcCTGGCCAA ccagccTGGCCAA ccaGCCTGGCcaa ccagccTGGCCAA ccagccTGGCCAA	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N	0.004 0.005 0.019 -0.058 0.023 0.012
69075266	rs4745583	T	C	hsa-miR-4492 hsa-miR-4498 hsa-miR-4743-5p hsa-miR-5001-5p hsa-miR-762	3 3 2 3 3	CCAGCCCggccaa CCAGCCCggccaa ccagcCCGGCCAa CCAGCCCggccaa CCAGCCCggccaa	Created Created Created Created Created	N N N N N	-0.014 -0.023 -0.123 -0.005 -0.005
69075287	rs147094532	A	G	hsa-miR-483-5p	0	aatCCCGTCTcta	Created	N	-0.118
69075287	rs147094532	A	A	hsa-miR-1273f hsa-miR-5089-5p	0	aatcCCATCTCta AATCCCAtctcta	Disrupted Disrupted	N N	-0.038 0.015
69075330	rs7865854	C	C	hsa-miR-3622a-5p	2	gtggttCGTGCCT	Disrupted	N	-0.096
69075330	rs7865854	C	T	hsa-miR-497-3p hsa-miR-5582-5p hsa-miR-6715a-3p	1 2 1	GTGGTTTgtgcct gtggttTGTGCCT gTGGTTTGtgcct	Created Created Created	N N N	0.132 -0.035 0.093
69075454	rs7866067	C
69075454	rs7866067	C	T	hsa-miR-4524a-3p hsa-miR-4797-5p	0	atactCTGTCTCA atACTCTGTctca	Created Created	N N	-0.071 0.011
69075463	rs72335845	-	-		0
69075463	rs72335845	-	TAAA	hsa-miR-4775	2	cgtctcAAATTAAaaaataaata	Unknown	N	0.2
69076047	rs7875564	C	A	hsa-miR-182-3p hsa-miR-377-5p hsa-miR-6086 hsa-miR-655-5p hsa-miR-7162-3p	0	ggTAGAACCtcag ggtagAACCTCAg ggtagAACCTCAg ggtagAACCTCAg ggtagaACCTCAG	Created Created Created Created Created	N N N N N	0.069 0.044 0.044 0.032 0.005
69076047	rs7875564	C	C	hsa-miR-1182 hsa-miR-6804-5p	0	ggtAGACCCTcag ggtagACCCTCAg	Disrupted Disrupted	N N	-0.009 -0.013
69076058	rs7875659	A	A	hsa-miR-299-3p hsa-miR-4474-3p hsa-miR-4482-3p hsa-miR-4491 hsa-miR-4657 hsa-miR-7159-3p	2 2 2 2 2 2	agCCACATAgaaa AGCCACAtagaaa agccacATAGAAA agCCACATAgaaa agCCACATAgaaa agccaCATAGAAA	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	LT N N N N N	0.01 -0.026 0.12 0.011 0.004 0.121
69076058	rs7875659	A
69076114	rs7858249	C	G	hsa-miR-1237-3p hsa-miR-1248 hsa-miR-6758-3p hsa-miR-6868-3p	0	aAGAAGGAatgag AAGAAGGAatgag aagaagGAATGAG aAGAAGGAAtgag	Created Created Created Created	N N N N	0.028 0.034 0.045 0.003
69076114	rs7858249	C	C	hsa-miR-103a-2-5p hsa-miR-3977 hsa-miR-4317	0	AAGAAGCAatgag aaGAAGCAAtgag aagaaGCAATGAg	Disrupted Disrupted Disrupted	N N N	0.042 -0.001 0.026
69076323	rs10781379	A	G	hsa-miR-4709-5p	0	acaACTGTTGttc	Created	N	0.013
69076323	rs10781379	A
69076751	rs141166099	C	C	hsa-miR-4462	2	ttagtCCGTGTCc	Disrupted	N	-0.118
69076751	rs141166099	C
69076752	rs150714901	G	G	hsa-miR-4462	2	tagtCCGTGTCca	Disrupted	N	-0.118
69076752	rs150714901	G	A	hsa-miR-4802-3p hsa-miR-6503-3p	2 2	tagTCCATGTcca TAGTCCAtgtcca	Created Created	N N	0.021 -0.034
69077000	rs141798960	C	C	hsa-miR-25-5p hsa-miR-6087 hsa-miR-658	1 1 1	aacCTCCGCCtcc aacctCCGCCTCc aaCCTCCGCctcc	Disrupted Disrupted Disrupted	N N N	-0.069 -0.068 -0.135
69077000	rs141798960	C	T	hsa-miR-1827 hsa-miR-1910-3p hsa-miR-2467-3p hsa-miR-3612 hsa-miR-4257 hsa-miR-650 hsa-miR-6511a-5p	1 1 1 1 1 1 1	aacctCTGCCTCc aaccTCTGCCTcc aaCCTCTGCctcc aacctcTGCCTCC aACCTCTGcctcc aacctcTGCCTCC aaccTCTGCCTcc	Created Created Created Created Created Created Created	N N N N N N N	0.005 0.09 -0.01 0.025 0.034 0.043 0.099
69077001	rs11145061	G	G	hsa-miR-25-5p hsa-miR-4695-5p hsa-miR-6087 hsa-miR-658	1 2 1 1	acCTCCGCCtcct acctccGCCTCCT acctCCGCCTCct aCCTCCGCctcct	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.069 0.057 -0.068 -0.135
69077001	rs11145061	G	A	hsa-miR-3689d hsa-miR-6134 hsa-miR-6851-5p hsa-miR-6880-5p hsa-miR-7847-3p	1 1 1 1 1	acctcCACCTCCt acctCCACCTCct acctcCACCTCCt acCTCCACCtcct aCCTCCACctcct	Created Created Created Created Created	N N N N N	0.092 -0.028 0.054 0.017 -0.036
69077164	rs7874105	G	C	hsa-miR-25-5p hsa-miR-3612 hsa-miR-6087 hsa-miR-650 hsa-miR-658	0	tgcCTCCGCCtcc TGCCTCCgcctcc tgcctCCGCCTCc TGCCTCCgcctcc tgCCTCCGCctcc	Created Created Created Created Created	N N N N N	-0.053 0.064 -0.065 0.082 -0.065
69077164	rs7874105	G	G	hsa-miR-6089	0	tgcctCGGCCTCc	Disrupted	N	-0.038
69077221	rs11145063	T	T	hsa-miR-3154 hsa-miR-3910 hsa-miR-605-3p	0	aatgCCTTCTAat aATGCCTTctaat aaTGCCTTCtaat	Disrupted Disrupted Disrupted	N N N	0.024 0.046 -0.041
69077221	rs11145063	T	G	hsa-miR-483-5p	0	aatgCCGTCTAat	Created	N	-0.062
69077356	rs35383713	-	-	hsa-miR-27b-5p hsa-miR-4453 hsa-miR-4538 hsa-miR-556-5p	3 3 3 2	tccAAGCTCAtat tCCAAGCTcatat tCCAAGCTcatat tccaAGCTCATAt	Unknown Unknown Unknown Unknown	N N N N	-0.001 0.003 0.003 -0.011
69077356	rs35383713	-	T	hsa-miR-100-3p hsa-miR-127-5p hsa-miR-3928-5p hsa-miR-6806-3p	3 3 3 3	tcCAAGCTTcatat tccaAGCTTCAtat tccaAGCTTCAtat tccaAGCTTCAtat	Unknown Unknown Unknown Unknown	N N N N	0.045 -0.015 0.023 0.016
69077564	rs60353555	A	A	hsa-miR-1248 hsa-miR-5088-3p hsa-miR-6851-3p hsa-miR-6886-3p	8 8 8 8	gcAAGAAGGgcct gcaAGAAGGGcct gcaagAAGGGCCt gcaaGAAGGGCct	Disrupted Disrupted Disrupted Disrupted	N N N N	0.156 0.068 -0.007 -0.042
69077564	rs60353555	A	C	hsa-miR-431-5p hsa-miR-4747-3p	6 6	GCAAGACgggcct gcaagaCGGGCCT	Created Created	N N	0.045 -0.116
69077895	rs11145068	A	A	hsa-miR-122-5p hsa-miR-143-5p hsa-miR-504-3p hsa-miR-6499-3p	2 1 2 1	cactgCACTCCAg cACTGCACtccag cactGCACTCCAg CACTGCActccag	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.013 No Change -0.108 0.016
69077895	rs11145068	A	T	hsa-miR-185-5p hsa-miR-2278 hsa-miR-4306 hsa-miR-4519 hsa-miR-4644 hsa-miR-5192	2 1 2 1 2 2	cactgCTCTCCAg caCTGCTCTccag cactgCTCTCCAg CACTGCTctccag cactgCTCTCCAg cactgCTCTCCAg	Created Created Created Created Created Created	N N N N N N	0.012 -0.015 0.012 0.019 0.022 0.008
69077896	rs151240103	C	C	hsa-miR-122-5p hsa-miR-143-5p hsa-miR-3135b hsa-miR-504-3p	2 1 2 2	actgCACTCCAgc ACTGCACtccagc actgcaCTCCAGC actGCACTCCAgc	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.013 No Change -0.103 -0.108
69077896	rs151240103	C	G	hsa-miR-1269a hsa-miR-1269b hsa-miR-1288-3p hsa-miR-17-3p hsa-miR-378a-3p hsa-miR-378b hsa-miR-378c hsa-miR-378d hsa-miR-378e hsa-miR-378f hsa-miR-378h hsa-miR-378i hsa-miR-422a hsa-miR-4418 hsa-miR-4515 hsa-miR-4740-5p hsa-miR-509-3-5p hsa-miR-509-5p	2 2 2 1 2 2 2 2 2 2 2 2 2 1 2 2 1 1	actgCAGTCCAgc actgCAGTCCAgc actGCAGTCCAgc ACTGCAGtccagc actgcAGTCCAGc actgcAGTCCAGc actgcAGTCCAGc actgcAGTCCAGc actgcAGTCCAGc actgcAGTCCAGc actgcAGTCCAGc actgcAGTCCAGc actgcAGTCCAGc aCTGCAGTccagc actgCAGTCCAgc actgCAGTCCAgc aCTGCAGTccagc aCTGCAGTccagc	Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created	N N N N N N N N N N N N N N N N N N	-0.002 0.017 -0.163 0.06 0.025 0.035 0.025 0.025 0.025 0.044 0.016 0.025 0.025 0.054 -0.01 -0.011 0.007 0.007
69077908	rs11145069	C	T	hsa-miR-500b-3p hsa-miR-6879-3p	0	cCTGGGTGAcaag cctGGGTGACAag	Created Created	N N	-0.087 -0.175
69077908	rs11145069	C	C	hsa-miR-3655	0	cctgggCGACAAG	Disrupted	N	-0.032
69077912	rs60780359	-	AA	hsa-miR-3655 hsa-miR-6879-3p	1 0	gggtGACAAGAggga GGGTGACAagaggga	Unknown Unknown	N N	0.021 -0.103
69077912	rs60780359	-	-	hsa-miR-4655-3p hsa-miR-6803-3p	1 1	gggtgACGAGGGA gggtgaCGAGGGA	Unknown Unknown	N N	-0.258 -0.135
69077930	rs35104955	A
69077930	rs35104955	A	G	hsa-miR-4263 hsa-miR-576-5p	1 1	ccaTTAGAAAaat ccATTAGAAAaat	Created Created	N N	0.11 0.167
69077946	rs11145070	G	G	hsa-miR-4462 hsa-miR-4681 hsa-miR-602	2 1 2	attcCCGTGTCtg aTTCCCGTgtctg attCCCGTGTctg	Disrupted Disrupted Disrupted	N N N	-0.133 -0.16 -0.202
69077946	rs11145070	G	A	hsa-miR-6716-5p	1	ATTCCCAtgtctg	Created	N	-0.022
69078163	rs10869823	G	C	hsa-miR-3919 hsa-miR-4797-5p hsa-miR-539-5p hsa-miR-600	0	atTTCTCTGtaag atttCTCTGTAag ATTTCTCtgtaag atttctCTGTAAG	Created Created Created Created	N N N N	-0.094 -0.026 0.071 -0.105
69078163	rs10869823	G	G	hsa-miR-3941 hsa-miR-466 hsa-miR-4672 hsa-miR-6768-5p	0	atttcTGTGTAAg atttcTGTGTAAg atttCTGTGTAAg atttCTGTGTAag	Disrupted Disrupted Disrupted Disrupted	N N N N	0.011 0.018 -0.091 -0.014
69078212	rs7866579	C	G	hsa-miR-215-3p hsa-miR-421 hsa-miR-4709-5p hsa-miR-505-3p hsa-miR-6773-3p	0	actgtTGACAGAg aCTGTTGAcagag ACTGTTGAcagag acTGTTGACAgag actgtTGACAGAg	Created Created Created Created Created	N N N N N	-0.018 -0.011 -0.024 -0.124 -0.02
69078212	rs7866579	C	C	hsa-miR-4677-3p hsa-miR-4679	0	actgtTCACAGAg actgtTCACAGAg	Disrupted Disrupted	N N	-0.01 -0.017
69078227	rs11145073	T	T	hsa-miR-101-5p hsa-miR-4703-3p	2 2	tATAACTAcaatg tatAACTACAatg	Disrupted Disrupted	N N	0.027 -0.032
69078227	rs11145073	T
69078351	rs116391013	C	C	hsa-miR-4475 hsa-miR-6757-5p hsa-miR-6892-5p	2 2 2	aaacaTCCCTTAa aaaCATCCCTtaa aaacaTCCCTTAA	Disrupted Disrupted Disrupted	N N N	-0.055 -0.16 -0.195
69078351	rs116391013	C	T	hsa-miR-1 hsa-miR-206 hsa-miR-33a-3p hsa-miR-4477b hsa-miR-613 hsa-miR-651-3p	2 2 2 2 2 2	aaACATTCCttaa aaACATTCCttaa AAACATTccttaa aaacatTCCTTAA aaACATTCCttaa aaacaTTCCTTAa	Created Created Created Created Created Created	N N N N N N	-0.118 -0.118 0.116 -0.123 -0.118 0.042
69078376	rs7039631	A	G	hsa-miR-3144-5p hsa-miR-3191-3p hsa-miR-4652-5p hsa-miR-6810-5p hsa-miR-7112-5p hsa-miR-92b-5p	0	ctgcccGTCCCCA ctgccCGTCCCCA ctgcccGTCCCCA ctgcccGTCCCCA CTGCCCGtcccca ctgcCCGTCCCca	Created Created Created Created Created Created	N N N N N N	-0.112 -0.257 -0.103 -0.062 -0.166 -0.165
69078376	rs7039631	A	A	hsa-miR-4450 hsa-miR-6721-5p hsa-miR-6857-5p	0	ctgcccATCCCCA CTGCCCAtcccca ctgcccATCCCCA	Disrupted Disrupted Disrupted	N N N	-0.085 -0.151 -0.06
69078531	rs75329120	G	G	hsa-miR-133a-3p hsa-miR-133b hsa-miR-370-3p hsa-miR-6893-3p	2 2 3 3	aagcaGGACCAAg aagcaGGACCAAg aAGCAGGAccaag aAGCAGGAccaag	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.125 -0.125 -0.086 -0.089
69078531	rs75329120	G	A	hsa-miR-152-5p hsa-miR-182-3p hsa-miR-218-1-3p hsa-miR-597-3p hsa-miR-6071 hsa-miR-659-3p hsa-miR-6828-3p	3 3 2 3 3 2 3	aagCAGAACCAag aagcAGAACCAag aagcaGAACCAAg aagcAGAACCAag aAGCAGAAccaag aagcaGAACCAAg aAGCAGAAccaag	Created Created Created Created Created Created Created	N N N N N N N	-0.224 -0.077 -0.057 -0.074 -0.055 -0.081 -0.068
69078608	rs79499353	A	A	hsa-miR-4422 hsa-miR-944	2 2	ataattATGCTTT ATAATTAtgcttt	Disrupted Disrupted	N N	-0.096 0.087
69078608	rs79499353	A	G	hsa-miR-6835-3p	2	ataattGTGCTTT	Created	N	-0.142

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Somatic mutations that impact miRNA target sites

Germline mutations in target sites of miRNAs in somatic mutation table

Genome Browser