SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_138457 |
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Gene Symbol: | FOXP4 |
Description: | Homo sapiens forkhead box P4 (FOXP4), transcript variant 1, mRNA. |
Gene Location: | chr6(+):41514163-41570122 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr6:g.41599783G>A | COSN7883038 | 8031704 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-615-5p |
gccaggctGGACCCCggct |
1 |
GGGGGUCC | m7b | Disrupted | -0.093000 | -0.005000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr6:g.41600484T>C | COSN1333090 | HCC85T | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-5093 |
ctccttggaCATTTCCcaa |
0 | AGGAAAUG | m7b | (m6c->m7b) | no TS | 0.103000 | No effect | |
hsa-miR-5093 |
ctccttggaCATTTCCcaa |
0 | AGGAAAUG | m7b | (m6c->m7b) | no TS | 0.103 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr6:g.41601557T>C | ICGC_DB0BC824-2A78-11E2-B303-24FD496BB9B8 | CPCG_0103_Pr_P_P6 | ProstateCancer(OICR,CA) | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1827 |
ctgcaacctCTGCCTCcca |
0 | UGAGGCAG | m7b | (m6c->m7b) | -0.277 | -0.349 |
-0.09 |
|
hsa-miR-2467-3p |
ctgcaaCCTCTGCctccca |
0 | AGCAGAGG | m7b | Created | -0.236 | -0.332 | No effect | |
hsa-miR-377-5p |
ctgCAACCTCTgcctccca |
0 | AGAGGUUG | m8a | Created | no TS | -0.007 |
-1.3 |
|
hsa-miR-4257 |
ctgcaACCTCTGcctccca |
0 | CCAGAGGU | m7b | Created | no TS | -0.047 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr6:g.41601680T>G | COSN2162176 | RK184_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-376c |
tcTCTATGTTggtcaggct |
1 |
AACAUAGA | m8a | (m8a->m7a) | -0.021000 | 0.006000 |
2.270000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
41599822 | rs71558753 | C | C |
hsa-miR-2467-3p hsa-miR-3158-5p hsa-miR-3678-3p hsa-miR-4418 hsa-miR-509-3-5p hsa-miR-509-5p hsa-miR-6758-5p hsa-miR-6856-5p |
2 2 2 3 3 3 2 2 |
gcctCTCTGCAgt gcctcTCTGCAGt gcctCTCTGCAgt gcctctCTGCAGT gcctctCTGCAGT gcctctCTGCAGT gCCTCTCTgcagt gCCTCTCTgcagt |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N |
0.009 0.025 0.002 -0.025 -0.025 -0.025 0.034 0.034 |
T |
hsa-miR-518a-5p hsa-miR-527 hsa-miR-583 |
2 2 2 |
gcctCTTTGCAgt gcctCTTTGCAgt gCCTCTTTgcagt |
Created Created Created |
N N N |
0.038 0.038 0.121 |
|||
41599889 | rs73733287 | C | C |
hsa-miR-6087 |
21 |
cttgcCCGCCTCt |
Disrupted |
N |
-0.059 |
T |
hsa-miR-1827 hsa-miR-4742-5p hsa-miR-6808-5p hsa-miR-6893-5p hsa-miR-940 |
21 1 3 3 3 |
cttgcCTGCCTCt cTTGCCTGcctct cttgCCTGCCTct cttgCCTGCCTct cttgCCTGCCTct |
Created Created Created Created Created |
N N N N N |
0.026 0.056 -0.012 -0.012 0.034 |
|||
41602100 | rs3747746 | A | A |
hsa-miR-1255a hsa-miR-1255b-5p hsa-miR-3681-5p hsa-miR-3691-5p hsa-miR-6744-5p hsa-miR-6849-5p hsa-miR-759 |
1 1 1 1 1 1 2 |
TCATCCActctgc TCATCCActctgc tcATCCACTctgc tCATCCACtctgc TCATCCActctgc tcATCCACTctgc tcatcCACTCTGc |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N |
-0.064 -0.064 -0.077 -0.208 -0.078 -0.114 -0.082 |
C |
hsa-miR-2467-3p hsa-miR-5187-5p |
2 1 |
tcatccCCTCTGC TCATCCCctctgc |
Created Created |
N N |
-0.198 -0.155 |
|||
41602105 | rs184271178 | G | G |
hsa-miR-2467-3p hsa-miR-3158-5p hsa-miR-3678-3p hsa-miR-759 |
1 1 1 2 |
caCTCTGCAggcc cacTCTGCAGgcc caCTCTGCAggcc CACTCTGcaggcc |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.061 -0.078 -0.088 -0.082 |
A |
hsa-miR-4732-5p hsa-miR-5586-3p hsa-miR-6735-3p hsa-miR-6832-5p |
1 2 3 1 |
caCTCTACAggcc CACTCTAcaggcc cactctACAGGCC caCTCTACAggcc |
Created Created Created Created |
N N N N |
-0.064 -0.079 -0.175 -0.043 |