SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001452
Gene Symbol: FOXF2
Description: Homo sapiens forkhead box F2 (FOXF2), mRNA.
Gene Location: chr6(+):1390068-1395832
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr6:g.1394887C>G COSN5273024 SNUH_G26_S1 [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-185-5p atggccgcTCTCTCCtctc
 0 UGGAGAGA m7b Disrupted -0.085000 no TS 4.190000
hsa-miR-2277-3p atggcCGCTGTCtcctctc
 0 UGACAGCG m7b Created no TS -0.160000 -9.710000
hsa-miR-4306 atggccgcTCTCTCCtctc
 0 UGGAGAGA m7b Disrupted -0.085000 no TS 3.830000
hsa-miR-4524a-3p atggccgCTGTCTCctctc
 0 UGAGACAG m7b Created no TS -0.071000 -2.250000
hsa-miR-4644 atggccgcTCTCTCCtctc
 0 UGGAGAGA m7b Disrupted -0.048000 no TS 1.810000

Mutation Mutation ID Sample Name Cancer Type
chr6:g.1394931G>A COSN1325757 HCC19T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-183-3p actgggacgAATTCAagtc
 0 GUGAAUUA m6b Created no TS 0.014000 -1.300000
hsa-miR-4452 actgggacGAATTCAAgtc
 0 UUGAAUUC m8a Created no TS -0.139000 -0.240000
hsa-miR-4800-3p actggGACGGATtcaagtc
 1
 CAUCCGUC m7b Disrupted -0.258000 no TS 5.550000
hsa-miR-183-3p actgggacgAATTCAagtc
 0 GUGAAUUA m6b Created no TS 0.014000 -1.300000
hsa-miR-4452 actgggacGAATTCAAgtc
 0 UUGAAUUC m8a Created no TS -0.139000 -0.240000
hsa-miR-4800-3p actggGACGGATtcaagtc
 1
 CAUCCGUC m7b Disrupted -0.258000 no TS 5.550000
hsa-miR-183-3p actgggacgAATTCAagtc
 0 GUGAAUUA m6b Created no TS 0.014 -1.3
hsa-miR-4452 actgggacGAATTCAAgtc
 0 UUGAAUUC m8a Created no TS -0.139 -0.24
hsa-miR-4800-3p actggGACGGATtcaagtc
 1
 CAUCCGUC m7b Disrupted -0.258 no TS 5.55

Mutation Mutation ID Sample Name Cancer Type
chr6:g.1395131G>T COSN2143833 RK035_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4503 gtgccaTGCTTAAggcatc
 0 UUUAAGCA m7b Created no TS -0.046000 -0.580000
hsa-miR-4503 gtgccaTGCTTAAggcatc
 0 UUUAAGCA m7b Created no TS -0.046 -0.58

Mutation Mutation ID Sample Name Cancer Type
chr6:g.1395204G>T COSN8493729 2275_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1323 agacaAGTTTTGtgtgtgt
 0 UCAAAACU m7b Created no TS -0.061000 No effect
hsa-miR-548o-3p agacaAGTTTTGtgtgtgt
 0 CCAAAACU m7b Created no TS -0.070000 No effect
hsa-miR-5582-3p agacAAGTTTTgtgtgtgt
 0 UAAAACUU m7b Created no TS 0.042000 -0.500000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
1394887 rs2293784 C C hsa-miR-185-5p
hsa-miR-4306
hsa-miR-4644
2
2
2
 gccgcTCTCTCCt
gccgcTCTCTCCt
gccgcTCTCTCCt
 Disrupted
Disrupted
Disrupted
N
N
N
 -0.085
-0.085
-0.048
G hsa-miR-2277-3p
hsa-miR-4524a-3p
4
2
 gcCGCTGTCtcct
gccgCTGTCTCct
 Created
Created
N
N
 -0.16
-0.071
1394949 rs115416648 G G hsa-miR-4536-3p
4
 ATGCACGcggata
 Disrupted
N
 -0.203
A hsa-miR-4800-3p
1
 atgcacACGGATA
 Created
N
 -0.216

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