SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001451
Gene Symbol: FOXF1
Description: Homo sapiens forkhead box F1 (FOXF1), mRNA.
Gene Location: chr16(+):86544132-86548070
Browse Associations

Somatic mutations that impact miRNA target sites




Mutation Mutation ID Sample Name Cancer Type
chr16:g.86513176C>T COSN4892789 PCSI_0052_Pa_X [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr16:g.86513257G>A COSN9445635 AOCS-168-1-8 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1184 cagcGCTGCAGttggcacc
0 CCUGCAGC m7b Created no TS -0.147000 -0.440000
hsa-miR-4418 cagcgCTGCAGTtggcacc
0 CACUGCAG m7b Created no TS -0.074000 -0.390000
hsa-miR-509-3-5p cagcgCTGCAGTtggcacc
0 UACUGCAG m7b Created no TS -0.092000 -0.200000
hsa-miR-509-5p cagcgCTGCAGTtggcacc
0 UACUGCAG m7b Created no TS -0.102000 -0.130000

Mutation Mutation ID Sample Name Cancer Type
chr16:g.86513506T>A COSN8393161 tumor_4120193 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-548a-5p attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA -0.010000
hsa-miR-548ab attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA -0.270000
hsa-miR-548ak attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA -1.370000
hsa-miR-548am-5p attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA -0.060000
hsa-miR-548ap-5p attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA 0.110000
hsa-miR-548ar-5p attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA -0.050000
hsa-miR-548as-5p attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA 0.090000
hsa-miR-548at-5p attatcaaaAACTTTTatt
10
AAAAGUUA m7a (m6b->m7a) 0.005000 0.005000 -0.010000
hsa-miR-548au-5p attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA -0.110000
hsa-miR-548av-5p attatcaaaTACTTTTatt
0 AAAAGUAC m7a (m7a->m6b) NA NA No effect
hsa-miR-548b-5p attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA No effect
hsa-miR-548c-5p attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA -0.060000
hsa-miR-548d-5p attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA -0.240000
hsa-miR-548h-5p attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA -0.230000
hsa-miR-548i attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA -0.030000
hsa-miR-548j attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA 0.060000
hsa-miR-548k attatcaaaTACTTTTatt
0 AAAAGUAC m7a (m7a->m6b) NA NA No effect
hsa-miR-548l attatcaaATACTTTTatt
7
AAAAGUAU m8a Disrupted -0.105000 no TS 1.750000
hsa-miR-548n attatcaaaTACTTTTatt
6
CAAAAGUA m7b (m7b->m6c) -0.086000 0.043000 -0.340000
hsa-miR-548o-5p attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA -0.060000
hsa-miR-548w attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA -0.030000
hsa-miR-548y attatcaaaTACTTTTatt
0 AAAAGUAA m7a (m7a->m6b) NA NA -0.200000
hsa-miR-561-3p attatcaaAAACTTTtatt
8
CAAAGUUU m7b Created 0.073000 -0.019000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr16:g.86513619G>C COSN7157698 8057528 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-223-3p gagcgggAACTGACAagag
0 UGUCAGUU m8a Created no TS -0.088000 -1.590000
hsa-miR-4277 gagcggGAACTGacaagag
0 GCAGUUCU m6b Created no TS 0.000000 -0.100000
hsa-miR-4697-3p gagcgggaACTGACAagag
0 UGUCAGUG m7a Created no TS -0.048000 -10.790000
hsa-miR-584-3p gagcgGGAACTGAcaagag
0 UCAGUUCC m8a Created no TS -0.140000 -4.990000
hsa-miR-668 gagcgggaAGTGACAagag
1
UGUCACUC m7a Disrupted -0.043000 no TS 0.180000

Mutation Mutation ID Sample Name Cancer Type
chr16:g.86513841T>C COSN5413406 RK134_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-330-3p tctgttaTGCTTTGtcttg
0 GCAAAGCA m7b Created no TS -0.106000 -1.150000
hsa-miR-4422 tctgttATGCTTTgtcttg
0 AAAAGCAU m7b Created no TS -0.081000 -1.940000
hsa-miR-4803 tctgTTATGTTttgtcttg
1
UAACAUAA m7b Disrupted 0.016000 no TS 10.270000

Mutation Mutation ID Sample Name Cancer Type
chr16:g.86513970G>A 9_98588 CRC-8-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5587-5p ccgGTGACCAcgcggattc
7
AUGGUCAC m7b (m6b->m7b) no TS -0.028 -3.9

Mutation Mutation ID Sample Name Cancer Type
chr16:g.86513993C>T COSN15435706 AOCS-150-8-X [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-20a-3p ttgcggggATGCAGaaagg
0 ACUGCAUU m6b Created no TS -0.056000 -0.360000
hsa-miR-324-5p ttgcgGGGATGCagaaagg
0 CGCAUCCC m7b Created no TS -0.318000 -4.820000
hsa-miR-4520a-5p ttgcggggACGCAGaaagg
8
CCUGCGUG m6b Disrupted -0.154000 no TS 0.130000
hsa-miR-4520b-5p ttgcggggACGCAGaaagg
8
CCUGCGUG m6b Disrupted -0.154000 no TS 0.130000
hsa-miR-544a ttgcggggaTGCAGAAagg
8
AUUCUGCA m7b (m6c->m7b) -0.044000 -0.185000 -2.170000
hsa-miR-20a-3p ttgcggggATGCAGaaagg
0 ACUGCAUU m6b Created no TS -0.056000 -0.360000
hsa-miR-324-5p ttgcgGGGATGCagaaagg
0 CGCAUCCC m7b Created no TS -0.318000 -4.820000
hsa-miR-4520a-5p ttgcggggACGCAGaaagg
8
CCUGCGUG m6b Disrupted -0.154000 no TS 0.130000
hsa-miR-4520b-5p ttgcggggACGCAGaaagg
8
CCUGCGUG m6b Disrupted -0.154000 no TS 0.130000
hsa-miR-544a ttgcggggaTGCAGAAagg
8
AUUCUGCA m7b (m6c->m7b) -0.044000 -0.185000 -2.170000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table

Location SNP ID Ancestral
Allele
Allele miR ID Conservation miRSite FuncClass Validation context+
score change
86513508 rs183461430 C C hsa-miR-548az-5p
hsa-miR-548l
hsa-miR-548n
hsa-miR-548t-5p
6
7
6
6
caaatACTTTTAt
caaATACTTTtat
caaaTACTTTTAt
caaatACTTTTAt
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
-0.008
-0.105
-0.135
-0.008
A hsa-miR-3163
hsa-miR-4282
hsa-miR-944
6
6
7
caaataATTTTAT
caaatAATTTTAt
caAATAATTttat
Created
Created
Created
N
N
N
-0.019
0.077
-0.044
86513509 rs148855296 T T hsa-miR-548az-5p
hsa-miR-548l
hsa-miR-548n
hsa-miR-548t-5p
6
7
6
6
aaatACTTTTAtt
aaATACTTTtatt
aaaTACTTTTAtt
aaatACTTTTAtt
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
-0.008
-0.105
-0.135
-0.008
86513839 rs142129039 T T hsa-miR-4803
1
ctgTTATGTTttg
Disrupted
N
0.016
C hsa-miR-194-5p
hsa-miR-424-3p
1
1
CTGTTACgttttg
ctgttACGTTTTg
Created
Created
N
N
-0.092
-0.1

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