SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_004119
Gene Symbol:	FLT3
Description:	Homo sapiens fms-related tyrosine kinase 3 (FLT3), mRNA.
Gene Location:	chr13(-):28577410-28674729
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Browse Pathways

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr13:g.28003652A>G			COSN6225534		RK190_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1255b-2-3p	tatttAGTGGTatatttta	0	AACCACUU	m6b	Created	no TS	-0.178000	3.940000
hsa-miR-1277-5p	tatttagtgATATATTTta	12	AAAUAUAU	m8a	(m8a->m7a)	-0.010000	no TS	-0.210000
hsa-miR-3074-3p	tatttagTGATATatttta	12	GAUAUCAG	m6b	Disrupted	-0.082000	no TS	0.010000
hsa-miR-34c-3p	tattTAGTGATatatttta	11	AAUCACUA	m7b	Disrupted	-0.281000	no TS	4.070000

Mutation			Mutation ID		Sample Name		Cancer Type
chr13:g.28003741A>G			COSN6225535		RK308_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3924	taaATACATAaaacaaaag	4	AUAUGUAU	m7b	(m7b->m6c)	-0.205000	no TS	0.670000

Mutation			Mutation ID		Sample Name		Cancer Type
chr13:g.28003822C>T			COSN6225536		RK150_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3145-5p	ttaTTGGAGTattgatctg	0	AACUCCAA	m7b	(m6c->m7b)	no TS	-0.381000	-8.100000
hsa-miR-5695	ttaTTGGAGTattgatctg	0	ACUCCAAG	m7a	(m6b->m7a)	NA	NA	-1.870000

Mutation			Mutation ID		Sample Name		Cancer Type
chr13:g.28003869T>G			COSN8778256		AOCS-155-3-5		[ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Mutation			Mutation ID		Sample Name		Cancer Type
chr13:g.28003929T>C			cosmic_v64_1760524				Leukemia/T-ALL
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Mutation			Mutation ID		Sample Name		Cancer Type
chr13:g.28003972A>G			cosmic_v64_1760520				Leukemia/T-ALL
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1245a	attaatttcATCACTaaaa	0	AAGUGAUC	m6b	Disrupted	-0.155	no TS	0.09

Mutation			Mutation ID		Sample Name		Cancer Type
chr13:g.28004003G>T			COSN4705634		PD3945a		[breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3120-3p	tccctaacaTGCTGTagat	0	CACAGCAA	m6b	Created	no TS	-0.125000	-3.990000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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