SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001144915
Gene Symbol: FGFR2
Description: Homo sapiens fibroblast growth factor receptor 2 (FGFR2), transcript variant 1, mRNA.
Gene Location: chr10(-):123237843-123356159
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr10:g.121478481G>A cosmic_v64_1760532 Leukemia/T-ALL
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-452-3p gccgtgcaAGATGAatgca
0 CUCAUCUG m6b Disrupted -0.051 no TS 4.9
hsa-miR-507 gccGTGCAAAAtgaatgca
0 UUUUGCAC m8a Created no TS -0.245 -0.36
hsa-miR-557 gccGTGCAAAatgaatgca
0 GUUUGCAC m7b (m6c->m7b) no TS -0.234 -0.36
hsa-miR-5696 gccgtgcaAAATGAatgca
0 CUCAUUUA m6b Created 0.05 0.085 No effect
hsa-miR-664-3p gccgtgcaaAATGAATgca
0 UAUUCAUU m7b (m6b->m7b) no TS -0.031 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.121478674A>T 9_18755 CRC-3-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3664-5p ttgaaacACAGAGTTgttc
6
AACUCUGU m8a Disrupted -0.153 no TS 7.0
hsa-miR-4302 ttgaaACACTGagttgttc
9
CCAGUGUG m6b Created -0.13 -0.223 -0.59

Mutation Mutation ID Sample Name Cancer Type
chr10:g.121478893C>T COSN1474325 RK157_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3653 accagcgtCTTCTTAaaag
16
CUAAGAAG m7b Created -0.028000 -0.122000 -0.040000
hsa-miR-3658 accagcgtcTTCTTAAAag
16
UUUAAGAA m8a (m7a->m8a) -0.043000 -0.068000 -0.010000
hsa-miR-3916 accagcgTCCTCTTaaaag
0 AAGAGGAA m7a Disrupted NA NA No effect
hsa-miR-5197-3p accagcgTCTTCTTaaaag
0 AAGAAGAG m7a Created NA NA No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.121479070G>T COSN5279480 RK095_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4775 ggggAAAATTAAgttttga
0 UUAAUUUU m8a Created no TS 0.129000 -0.880000
hsa-miR-5696 ggggaAAATGAagttttga
6
CUCAUUUA m6b Disrupted 0.050000 no TS No effect
hsa-miR-590-3p ggggAAAATTAagttttga
0 UAAUUUUA m7a Created no TS 0.114000 -0.070000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.121479183G>T cosmic_v64_1760521 Leukemia/T-ALL
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3117-5p atttaAGTGTCatttctat
0 AGACACUA m6b Created no TS -0.153 -3.01
hsa-miR-425-5p atttaaGTGTCATTtctat
0 AAUGACAC m8a Created no TS -0.211 -0.71
hsa-miR-4252 atttaAGTGGCatttctat
0 GGCCACUG m6b Disrupted -0.17 no TS 6.97

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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