SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_000141
Gene Symbol: FGFR2
Description: Homo sapiens fibroblast growth factor receptor 2 (FGFR2), transcript variant 1, mRNA.
Gene Location: chr10(-):123237843-123357972
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr10:g.121478481G>A cosmic_v64_1760532 Leukemia/T-ALL
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-452-3p gccgtgcaAGATGAatgca
 0 CUCAUCUG m6b Disrupted -0.051 no TS 4.9
hsa-miR-507 gccGTGCAAAAtgaatgca
 0 UUUUGCAC m8a Created no TS -0.245 -0.05
hsa-miR-557 gccGTGCAAAatgaatgca
 0 GUUUGCAC m7b (m6c->m7b) no TS -0.234 -0.24
hsa-miR-5696 gccgtgcaAAATGAatgca
 0 CUCAUUUA m6b Created 0.076 0.111 No effect
hsa-miR-664-3p gccgtgcaaAATGAATgca
 0 UAUUCAUU m7b (m6b->m7b) no TS -0.031 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.121478674A>T 9_18755 CRC-3-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3664-5p ttgaaacACAGAGTTgttc
 6
 AACUCUGU m8a Disrupted -0.153 no TS 7.0
hsa-miR-4302 ttgaaACACTGagttgttc
 9
 CCAGUGUG m6b Created -0.191 -0.284 -0.01

Mutation Mutation ID Sample Name Cancer Type
chr10:g.121478893C>T COSN1474325 RK157_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3653 accagcgtCTTCTTAaaag
 16
 CUAAGAAG m7b Created 0.002000 -0.092000 -0.040000
hsa-miR-3658 accagcgtcTTCTTAAAag
 16
 UUUAAGAA m8a (m7a->m8a) -0.004000 -0.029000 -0.010000
hsa-miR-3916 accagcgTCCTCTTaaaag
 0 AAGAGGAA m7a Disrupted NA NA No effect
hsa-miR-5197-3p accagcgTCTTCTTaaaag
 0 AAGAAGAG m7a Created NA NA No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.121479070G>T COSN5279480 RK095_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4775 ggggAAAATTAAgttttga
 0 UUAAUUUU m8a Created no TS 0.187000 -0.540000
hsa-miR-5696 ggggaAAATGAagttttga
 6
 CUCAUUUA m6b Disrupted 0.076000 no TS No effect
hsa-miR-590-3p ggggAAAATTAagttttga
 0 UAAUUUUA m7a Created no TS 0.140000 -0.070000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.121479183G>T cosmic_v64_1760521 Leukemia/T-ALL
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3117-5p atttaAGTGTCatttctat
 0 AGACACUA m6b Created no TS -0.123 -3.01
hsa-miR-425-5p atttaaGTGTCATTtctat
 0 AAUGACAC m8a Created no TS -0.172 -0.71
hsa-miR-4252 atttaAGTGGCatttctat
 0 GGCCACUG m6b Disrupted -0.14 no TS 6.97

Mutation Mutation ID Sample Name Cancer Type
chr10:g.121479598C>T ICGC_snv_2986 GC8_T [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-323b-3p ccgtgcGTATTGGctgtgg
 0 CCCAAUAC m7b Created no TS -0.041 -0.22
hsa-miR-4676-5p ccgtgcgtACTGGCTgtgg
 0 GAGCCAGU m7b Disrupted -0.132 no TS 0.31
hsa-miR-4712-5p ccgtgcGTACTGGctgtgg
 0 UCCAGUAC m7b Disrupted -0.078 no TS No effect
hsa-miR-575 ccgtgcgtACTGGCTgtgg
 0 GAGCCAGU m7b Disrupted -0.151 no TS 0.03
hsa-miR-770-5p ccgtgcGTACTGGctgtgg
 0 UCCAGUAC m7b Disrupted -0.106 no TS 0.35

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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