SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_000136
Gene Symbol:	FANCC
Description:	Homo sapiens Fanconi anemia, complementation group C (FANCC), transcript variant 1, mRNA.
Gene Location:	chr9(-):97861335-98079991

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.95099161C>G			COSN2334589		RK026_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-21-3p	ccaaccagGGTGTTattcc	0	CAACACCA	m6b	Created	no TS	-0.103000	-0.020000
hsa-miR-3591-3p	ccaaccagGGTGTTattcc	0	AAACACCA	m6b	Created	no TS	-0.089000	-0.010000
hsa-miR-3620	ccaacCAGGGTGttattcc	1	UCACCCUG	m7b	Created	-0.131000	-0.319000	No effect
hsa-miR-21-3p	ccaaccagGGTGTTattcc	0	CAACACCA	m6b	Created	no TS	-0.103	-0.02
hsa-miR-3591-3p	ccaaccagGGTGTTattcc	0	AAACACCA	m6b	Created	no TS	-0.089	-0.01
hsa-miR-3620	ccaacCAGGGTGttattcc	0	UCACCCUG	m7b	Created	-0.131	-0.319	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.95100080A>C			COSN7578530		8048316		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-149-5p	ctgactttaAGCCAGAact	0	UCUGGCUC	m7a	(m7a->m6a)	-0.263000	-0.207000	0.380000
hsa-miR-3064-5p	ctgactttaAGCCAGAact	1	UCUGGCUG	m7a	(m7a->m6a)	-0.042000	0.003000	No effect
hsa-miR-4794	ctgactttaAGCCAGAact	2	UCUGGCUA	m7a	(m7a->m6a)	-0.056000	no TS	0.320000
hsa-miR-664-5p	ctgactttaAGCCAGaact	2	ACUGGCUA	m6b	Disrupted	-0.056000	no TS	0.010000

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.95100373A>T			COSN9288154		C0051T		[kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4275	aatgcTAATTGatccactg	0	CCAAUUAC	m6b	Created	no TS	0.117000	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.95100903G>A			ICGC_81286CA4-2A78-11E2-96E7-04FD496BB9B8		CPCG_0102_Pr_P_P1		ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-450b-3p	cacacctgtGATCCCAgca	0	UUGGGAUC	m7b	(m7b->m6b)	-0.068	no TS	1.86
hsa-miR-5089	cacacctgtAATCCCAgca	0	GUGGGAUU	m7b	(m6b->m7b)	-0.021	-0.018	0.03
hsa-miR-513a-5p	cacaCCTGTGAtcccagca	0	UUCACAGG	m7b	Disrupted	-0.046	no TS	0.01
hsa-miR-638	cacacctgtGATCCCagca	0	AGGGAUCG	m6b	Disrupted	-0.075	no TS	1.27
hsa-miR-769-3p	cacacctgtGATCCCAGca	0	CUGGGAUC	m8a	(m8a->m7a)	-0.087	no TS	0.79

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.95101277T>C			COSN5708455		RK082_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4294	tttAGACTCCttttaggag	0	GGGAGUCU	m7b	(m6c->m7b)	no TS	-0.253000	No effect
hsa-miR-5007-5p	tttAGACTCTttttaggag	0	UAGAGUCU	m7b	(m7b->m6c)	-0.369000	-0.148000	No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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