| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_138389 |
|---|---|
| Gene Symbol: | FAM114A1 |
| Description: | Homo sapiens family with sequence similarity 114, member A1 (FAM114A1), transcript variant 1, mRNA. |
| Gene Location: | chr4(+):38869353-38947365 |
| Browse Associations | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr4:g.38943838A>G | COSN1296792 | HCC82T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr4:g.38944014A>T | COSN2027869 | RK049_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1245a |
gcaaaaatATCACTactta |
0 | AAGUGAUC | m6b | Created | no TS | -0.105000 | No effect | |
| hsa-miR-142-3p |
gcaaaaataACACTACtta |
0 | UGUAGUGU | m7b | (m7b->m6c) | -0.570000 | -0.321000 |
0.250000 |
|
| hsa-miR-3145-3p |
gcaaAAATATCactactta |
3 |
AGAUAUUU | m7b | Created | -0.003000 | -0.091000 |
-0.410000 |
|
| hsa-miR-3689a-5p |
gcaaaaATATCACtactta |
0 | UGUGAUAU | m7b | Created | no TS | -0.186000 |
-1.870000 |
|
| hsa-miR-3689b-5p |
gcaaaaATATCACtactta |
0 | UGUGAUAU | m7b | Created | no TS | -0.186000 |
-1.870000 |
|
| hsa-miR-3689e |
gcaaaaATATCACtactta |
0 | UGUGAUAU | m7b | Created | no TS | -0.186000 |
-1.870000 |
|
| hsa-miR-3689f |
gcaaaaATATCACtactta |
0 | UGUGAUAU | m7b | Created | no TS | -0.186000 |
-1.070000 |
|
| hsa-miR-4255 |
gcaaaaatAACACTactta |
0 | CAGUGUUC | m6b | Disrupted | -0.371000 | -0.289000 |
-0.010000 |
|
| hsa-miR-1245a |
gcaaaaatATCACTactta |
0 | AAGUGAUC | m6b | Created | no TS | -0.105 | No effect | |
| hsa-miR-142-3p |
gcaaaaataACACTACtta |
0 | UGUAGUGU | m7b | (m7b->m6c) | -0.57 | -0.321 |
0.25 |
|
| hsa-miR-3145-3p |
gcaaAAATATCactactta |
0 | AGAUAUUU | m7b | Created | -0.003 | -0.091 |
-0.41 |
|
| hsa-miR-3689a-5p |
gcaaaaATATCACtactta |
0 | UGUGAUAU | m7b | Created | no TS | -0.186 |
-1.87 |
|
| hsa-miR-3689b-5p |
gcaaaaATATCACtactta |
0 | UGUGAUAU | m7b | Created | no TS | -0.186 |
-1.87 |
|
| hsa-miR-3689e |
gcaaaaATATCACtactta |
0 | UGUGAUAU | m7b | Created | no TS | -0.186 |
-1.87 |
|
| hsa-miR-3689f |
gcaaaaATATCACtactta |
0 | UGUGAUAU | m7b | Created | no TS | -0.186 |
-1.07 |
|
| hsa-miR-4255 |
gcaaaaatAACACTactta |
0 | CAGUGUUC | m6b | Disrupted | -0.371 | -0.289 |
-0.01 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr4:g.38944909T>C | COSN5570675 | RK057_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-4694-5p |
ggcttaaAACACCaataaa |
0 | AGGUGUUA | m6b | Created | no TS | -0.096000 | No effect | |
| hsa-miR-5681b |
ggcttaaAATACCaataaa |
3 |
AGGUAUUG | m6b | Disrupted | -0.048000 | no TS |
0.110000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr4:g.38945329C>A | COSN14843120 | 8057559 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1915-5p |
ccctgcGGCAAGGaggggc |
0 | ACCUUGCC | m7b | Created | no TS | -0.224000 |
-0.020000 |
|
| hsa-miR-221-5p |
ccctgcgGCCAGGaggggc |
2 |
ACCUGGCA | m6b | Disrupted | -0.213000 | -0.122000 | No effect | |
| hsa-miR-502-5p |
ccctgcgGCAAGGAggggc |
0 | AUCCUUGC | m7b | Created | no TS | -0.055000 | No effect | |
| hsa-miR-660-3p |
ccctgcggcCAGGAGGggc |
3 |
ACCUCCUG | m7b | (m7b->m6c) | -0.047000 | no TS | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr4:g.38945330A>G | COSN14843125 | 8057559 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-221-5p |
cctgcgGCCAGGaggggca |
2 |
ACCUGGCA | m6b | Disrupted | -0.213000 | -0.122000 | No effect | |
| hsa-miR-4667-3p |
cctgcggccAGGAGGGgca |
3 |
UCCCUCCU | m7b | (m7b->m6c) | -0.058000 | no TS |
-0.700000 |
|
| hsa-miR-660-3p |
cctgcggcCAGGAGGggca |
3 |
ACCUCCUG | m7b | Disrupted | -0.047000 | no TS | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr4:g.38945391T>A | 11_5884 | 2542 | Breast cancer | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-487b |
gctgcatGTACGATacaat |
0 | AAUCGUAC | m7b | Created | no TS | -0.411 |
-0.03 |
|
| hsa-miR-5686 |
gctgcatgTACGATAcaat |
0 | UAUCGUAU | m7a | Created | no TS | -0.149 |
-3.14 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr4:g.38945690C>T | COSN6830204 | RK181_C01 | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-let-7a-2-3p |
ctttaTGTACAatctggaa |
2 |
CUGUACAG | m6b | Disrupted | -0.109000 | no TS | No effect |
| hsa-let-7a-3p |
ctttaTGTATAatctggaa |
2 |
CUAUACAA | m6b | Created | -0.059000 | -0.127000 |
-0.510000 |
| hsa-let-7b-3p |
ctttaTGTATAatctggaa |
2 |
CUAUACAA | m6b | Created | -0.059000 | -0.120000 |
-0.060000 |
| hsa-let-7f-1-3p |
ctttaTGTATAatctggaa |
2 |
CUAUACAA | m6b | Created | -0.069000 | -0.130000 |
-0.450000 |
| hsa-let-7f-2-3p |
ctttaTGTATAatctggaa |
2 |
CUAUACAG | m6b | Created | -0.067000 | -0.143000 |
-0.810000 |
| hsa-let-7g-3p |
ctttaTGTACAatctggaa |
2 |
CUGUACAG | m6b | Disrupted | -0.112000 | no TS |
0.510000 |
| hsa-miR-1185-1-3p |
ctttaTGTATAatctggaa |
2 |
AUAUACAG | m6b | Created | -0.080000 | -0.156000 |
-0.260000 |
| hsa-miR-1185-2-3p |
ctttaTGTATAatctggaa |
2 |
AUAUACAG | m6b | Created | -0.080000 | -0.149000 |
-0.150000 |
| hsa-miR-4789-5p |
ctttaTGTATAatctggaa |
2 |
GUAUACAC | m6b | Created | -0.287000 | -0.358000 |
-0.340000 |
| hsa-miR-493-5p |
ctttATGTACAAtctggaa |
2 |
UUGUACAU | m8a | Disrupted | -0.339000 | no TS |
0.100000 |
| hsa-miR-508-3p |
ctttatgTACAATCtggaa |
5 |
UGAUUGUA | m7b | Disrupted | -0.179000 | no TS |
0.140000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 38945236 | rs192759984 | T | T |
hsa-miR-1272 hsa-miR-3145-3p hsa-miR-3682-3p |
1 1 1 |
caaataTCATCAT cAAATATCAtcat caaaTATCATCAt |
Disrupted Disrupted Disrupted |
N N N |
-0.094 0.043 -0.186 |
| C |
hsa-miR-5681b hsa-miR-8069 |
1 1 |
caAATACCAtcat caaatACCATCAt |
Created Created |
N N |
-0.033 -0.099 |
|||
| 38945328 | rs146024101 | - | C |
hsa-miR-221-5p hsa-miR-8073 |
6 6 |
ctgcgGCCAGGAg ctgcgGCCAGGAg |
Unknown Unknown |
N N |
-0.091 -0.105 |
| - |
hsa-miR-1976 hsa-miR-4722-3p hsa-miR-6727-3p hsa-miR-6747-3p |
6 2 2 2 |
ctgcgGCAGGAG ctgcGGCAGGAg ctgcGGCAGGAg ctgcGGCAGGAg |
Unknown Unknown Unknown Unknown |
N N N N |
-0.043 -0.09 -0.09 -0.088 |
|||
| 38945334 | rs74483769 | G | G |
hsa-miR-210-5p hsa-miR-4667-3p hsa-miR-4749-3p hsa-miR-660-3p hsa-miR-6887-3p |
1 3 1 3 2 |
ccaggAGGGGCAt ccAGGAGGGgcat ccagGAGGGGCAt cCAGGAGGggcat ccaGGAGGGGcat |
Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N |
-0.16 -0.058 -0.359 -0.047 -0.173 |
| A |
hsa-miR-1343-3p hsa-miR-3667-3p hsa-miR-6783-3p hsa-miR-6886-3p hsa-miR-938 |
4 3 4 1 1 |
CCAGGAAgggcat ccAGGAAGGgcat CCAGGAAgggcat ccagGAAGGGCAt ccaggAAGGGCAt |
Created Created Created Created Created |
N N N N N |
-0.053 -0.063 -0.043 -0.292 -0.11 |