SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_000124 |
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Gene Symbol: | ERCC6 |
Description: | Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 6 (ERCC6), mRNA. |
Gene Location: | chr10(-):50664490-50747147 |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr10:g.49457119G>A | COSN5875651 | RK187_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1295b-3p |
taatcattaGCCTATaagg |
4 |
AAUAGGCC | m6b | Disrupted | -0.142000 | no TS |
1.510000 |
|
hsa-miR-569 |
taatCATTAACctataagg |
0 | AGUUAAUG | m7b | Created | no TS | -0.104000 |
-0.500000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr10:g.49457844C>G | COSN5875652 | RK220_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-921 |
tgtttgtatCTCACTActg |
1 |
CUAGUGAG | m7b | (m7b->m6b) | -0.108000 | no TS |
3.010000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr10:g.49458407A>G | COSN1490992 | RK007_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4724-5p |
acctGTTCAGTaagttcat |
0 | AACUGAAC | m7b | Created | no TS | -0.255000 | No effect | |
hsa-miR-4724-5p |
acctGTTCAGTaagttcat |
0 | AACUGAAC | m7b | Created | no TS | -0.255 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr10:g.49458583T>- | ICGC_ssm_v3_24605 | HCC100T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-192-3p |
ttttttttTTGGCAatcta |
0 | CUGCCAAU | m6b | Disrupted | -0.179000 | -0.178000 |
-0.270000 |
hsa-miR-3613-3p |
ttttTTTTTTGgcaatcta |
0 | ACAAAAAA | m7b | Disrupted | 0.174000 | 0.176000 |
-0.410000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
49457119 | rs192300032 | G | G |
hsa-miR-1295b-3p |
4 |
tcattaGCCTATA |
Disrupted |
N |
-0.142 |