SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001983
Gene Symbol: ERCC1
Description: Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ERCC1), transcript variant 3, mRNA.
Gene Location: chr19(-):45910590-45927177
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr19:g.45408924T>C ICGC_1440095 TCGA-AP-A0LM-01A-11D-A122-09 UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1275 atggctTCCCCCAgtggct
 0 GUGGGGGA m7b Created -0.061 -0.148 No effect
hsa-miR-3928 atggcTTCCTCCagtggct
 0 GGAGGAAC m7a Disrupted -0.368 -0.368 1.8
hsa-miR-4271 atggCTTCCCCCagtggct
 0 GGGGGAAG m8a Created no TS -0.015 No effect
hsa-miR-4525 atggctTCCCCCagtggct
 0 GGGGGGAU m6b Created no TS -0.088 No effect
hsa-miR-4665-5p atggctTCCCCCAGtggct
 0 CUGGGGGA m8a Created -0.061 -0.139 No effect
hsa-miR-4725-3p atggCTTCCCCcagtggct
 0 UGGGGAAG m7b Created no TS -0.015 No effect
hsa-miR-5010-5p atggctTCCCCCagtggct
 0 AGGGGGAU m6b Created no TS -0.078 0.01
hsa-miR-625-5p atggcTTCCCCCagtggct
 0 AGGGGGAA m7b Created no TS -0.138 No effect
hsa-miR-637 atggcttCCCCCAGTggct
 0 ACUGGGGG m8a Created -0.435 -0.583 No effect
hsa-miR-671-5p atGGCTTCCTccagtggct
 0 AGGAAGCC m8a (m8a->m7b) -0.093 -0.066 No effect
hsa-miR-766-5p atggcTTCCTCCagtggct
 0 AGGAGGAA m7b Disrupted -0.065 no TS 0.02

Mutation Mutation ID Sample Name Cancer Type
chr19:g.45409063C>T ICGC_1440096 TCGA-AX-A0J1-01A-11W-A062-09 UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-183-5p ctgttgagGTGCCATggtc
 0 UAUGGCAC m7b Created no TS -0.039 -0.01
hsa-miR-566 ctgttgAGGCGCCatggtc
 0 GGGCGCCU m7b Disrupted -0.409 no TS 0.01
hsa-miR-593-5p ctgttgaGGTGCCatggtc
 0 AGGCACCA m6b Created no TS -0.116 -7.62
hsa-miR-652-3p ctgttgagGCGCCATggtc
 0 AAUGGCGC m7b Disrupted -0.159 no TS 0.12

Mutation Mutation ID Sample Name Cancer Type
chr19:g.45409255G>G ICGC_64548 TCGA-GV-A3JX-01A-11D-A20D-08 BladderUrothelialCarcinoma(TCGA,US)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4257 gtgACCTCTGtctttcttc
 0 CCAGAGGU m7b (m6c->m7b) -0.061 -0.226 -0.06
hsa-miR-4311 gtgacctcTCTCTTTCttc
 0 GAAAGAGA m8a Disrupted 0 0.006 0.07

Mutation Mutation ID Sample Name Cancer Type
chr19:g.45409420C>T ICGC_1440097 TCGA-AX-A0J1-01A-11W-A062-09 UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-181a-2-3p atTCAGTGGTggccctggc
 0 ACCACUGA m8a (m7b->m8a) -0.124 -0.151 -0.36
hsa-miR-4252 attCAGTGGCggccctggc
 0 GGCCACUG m7b (m7b->m6c) -0.494 -0.314 1.87

Mutation Mutation ID Sample Name Cancer Type
chr19:g.45409460G>A ICGC_1440098 TCGA-AP-A0LE-01A-11D-A127-09 UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1302 tctTGTCCCAgcctgtggg
 0 UUGGGACA m7b (m6c->m7b) no TS -0.124 -0.14
hsa-miR-4298 tctTGTCCCAGcctgtggg
 0 CUGGGACA m8a Created no TS -0.152 -0.39
hsa-miR-4438 tcttgtcccAGCCTGTGgg
 0 CACAGGCU m8a (m7a->m8a) no TS -0.083 0.15
hsa-miR-4505 tcttgtCCCAGCCTgtggg
 0 AGGCUGGG m8a Created -0.377 -0.6 -0.33

Mutation Mutation ID Sample Name Cancer Type
chr19:g.45409554G>C COSN8973610 AOCS-166-1-2 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4726-5p cttctggTGGCCCaggtgg
 6
 AGGGCCAG m6b Disrupted -0.155000 no TS No effect
hsa-miR-486-3p cttctggTGCCCCaggtgg
 0 CGGGGCAG m6b Created no TS -0.148000 No effect
hsa-miR-593-5p cttcTGGTGCCccaggtgg
 0 AGGCACCA m7b Created no TS -0.182000 -0.130000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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