SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_001142615
Gene Symbol:	EHBP1
Description:	Homo sapiens EH domain binding protein 1 (EHBP1), transcript variant 2, mRNA.
Gene Location:	chr2(+):62900985-63273621
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.63045589T>C			COSN166115		GC8_T		[stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-548at-5p	ttaaAACTTTTaacatttt	0	AAAAGUUA	m7a	Disrupted	NA	NA	No effect
hsa-miR-548n	ttaaaACTTTTaacatttt	7	CAAAAGUA	m6b	Disrupted	-0.021000	no TS	0.020000
hsa-miR-548t-5p	ttaaaACTTTTaacatttt	7	CAAAAGUG	m6b	Disrupted	-0.026000	no TS	No effect
hsa-miR-561-3p	ttaAAACTTTtaacatttt	8	CAAAGUUU	m7b	(m7b->m6b)	-0.211000	-0.071000	No effect
hsa-miR-548at-5p	ttaaAACTTTTaacatttt	0	AAAAGUUA	m7a	Disrupted	NA	NA	No effect
hsa-miR-548n	ttaaaACTTTTaacatttt	7	CAAAAGUA	m6b	Disrupted	-0.021	no TS	0.02
hsa-miR-548t-5p	ttaaaACTTTTaacatttt	7	CAAAAGUG	m6b	Disrupted	-0.026	no TS	No effect
hsa-miR-561-3p	ttaAAACTTTtaacatttt	8	CAAAGUUU	m7b	(m7b->m6b)	-0.211	-0.071	No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
63045589	rs2018650	T	T	hsa-miR-548az-5p hsa-miR-548n hsa-miR-548t-5p hsa-miR-561-3p	7 7 7 8	aaACTTTTAacat aaACTTTTAacat aaACTTTTAacat AAACTTTtaacat	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.026 -0.021 -0.026 -0.14

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