SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_021937
Gene Symbol: EEFSEC
Description: Homo sapiens eukaryotic elongation factor, selenocysteine-tRNA-specific (EEFSEC), mRNA.
Gene Location: chr3(+):127872312-128127489
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr3:g.128408443G>A EEFSEC_E7_UTR_3 SJHYPO029_D Hypodiploid_ALL
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-221-5p ctgggGCCAGGagggtctc
 4
 ACCUGGCA m6b Disrupted -0.11 no TS -11.45
hsa-miR-4667-3p ctggggccAGGAGGGtctc
 0 UCCCUCCU m7b Disrupted -0.126 no TS 3.02
hsa-miR-660-3p ctggggcCAGGAGGgtctc
 5
 ACCUCCUG m7b Disrupted -0.072 no TS -8.61

Mutation Mutation ID Sample Name Cancer Type
chr3:g.128408546G>T COSN7816736 8069321 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2110 tcttccacTTCCCCAtctg
 0 UUGGGGAA m7b Created no TS -0.128000 -11.160000
hsa-miR-34a-5p tcttcCACTGCCccatctg
 2
 UGGCAGUG m7b Disrupted -0.185000 no TS 5.420000
hsa-miR-34c-5p tcttcCACTGCCccatctg
 2
 AGGCAGUG m7b Disrupted -0.166000 no TS 3.540000
hsa-miR-3675-5p tcttccactGCCCCATctg
 2
 UAUGGGGC m7b (m7b->m6c) -0.246000 no TS -2.740000
hsa-miR-4271 tcttccaCTTCCCCatctg
 0 GGGGGAAG m7b Created no TS -0.369000 No effect
hsa-miR-449a tcttcCACTGCCccatctg
 2
 UGGCAGUG m7b Disrupted -0.166000 no TS 3.420000
hsa-miR-449b-5p tcttcCACTGCCccatctg
 2
 AGGCAGUG m7b Disrupted -0.176000 no TS 4.900000
hsa-miR-4725-3p tcttccaCTTCCCCAtctg
 0 UGGGGAAG m8a Created no TS -0.369000 No effect
hsa-miR-4795-5p tcttCCACTTCcccatctg
 0 AGAAGUGG m7b Created no TS -0.167000 0.260000
hsa-miR-486-3p tcttccaCTGCCCCatctg
 2
 CGGGGCAG m7b Disrupted -0.471000 no TS -0.100000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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