SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001122659
Gene Symbol: EDNRB
Description: Homo sapiens endothelin receptor type B (EDNRB), transcript variant 1, mRNA.
Gene Location: chr13(-):78469615-78492966
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr13:g.77896139G>A COSN7418428 8033471 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4495 agcatacTTACATTattta
4
AAUGUAAA m7a Created 0.002000 0.002000 -2.180000

Mutation Mutation ID Sample Name Cancer Type
chr13:g.77896433C>T COSN5264697 SNUH_G26_S1 [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1272 attcacaCATCATatggat
0 GAUGAUGA m6b Created no TS -0.009000 -0.020000
hsa-miR-1322 attcacaCATCATatggat
0 GAUGAUGC m6b Created no TS -0.022000 -0.360000
hsa-miR-3650 attcACACACCatatggat
1
AGGUGUGU m7b Disrupted -0.220000 no TS 2.010000

Mutation Mutation ID Sample Name Cancer Type
chr13:g.77896630T>C COSN8587837 3093_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5705 ctttCGAAACAaattgggc
0 UGUUUCGG m7a Created no TS -0.079000 -8.770000

Mutation Mutation ID Sample Name Cancer Type
chr13:g.77896856A>T COSN6633873 CHC197T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3185 aatttttatTTCTTCTaag
2
AGAAGAAG m7a (m6a->m7a) -0.095000 -0.095000 -0.130000
hsa-miR-4699-5p aatttttatATCTTCTaag
2
AGAAGAUU m7a (m7a->m6a) -0.109000 -0.109000 0.380000

Mutation Mutation ID Sample Name Cancer Type
chr13:g.77897009C>A COSN9471017 C0086T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5095 taacagctaCCTGTAAagc
7
UUACAGGC m7a (m7a->m6a) -0.006000 no TS No effect
hsa-miR-552 taacagctACCTGTaaagc
7
AACAGGUG m6b Disrupted -0.045000 no TS No effect
hsa-miR-582-5p taacagctAACTGTAAagc
8
UUACAGUU m8a Created -0.078000 -0.081000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr13:g.77897045T>A COSN1626461 RK024_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5585-3p aatactatTATTCAaaatc
2
CUGAAUAG m6b Created -0.166000 -0.144000 -0.030000
hsa-miR-633 aatACTATTAttcaaaatc
1
CUAAUAGU m7b (m6c->m7b) -0.275000 -0.328000 -0.050000
hsa-miR-5585-3p aatactatTATTCAaaatc
2
CUGAAUAG m6b Created -0.166000 -0.144000 -0.030000
hsa-miR-633 aatACTATTAttcaaaatc
1
CUAAUAGU m7b (m6c->m7b) -0.275000 -0.328000 -0.050000
hsa-miR-5585-3p aatactatTATTCAaaatc
0 CUGAAUAG m6b Created -0.166 -0.144 -0.03
hsa-miR-633 aatACTATTAttcaaaatc
0 CUAAUAGU m7b (m6c->m7b) -0.275 -0.328 -0.05

Mutation Mutation ID Sample Name Cancer Type
chr13:g.77897228A>T COSN1626462 RK023_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5696 agatgatTAAATGAGggca
6
CUCAUUUA m8a Disrupted -0.042000 -0.141000 No effect
hsa-miR-5696 agatgatTAAATGAGggca
0 CUCAUUUA m8a Disrupted -0.042 -0.141 No effect

Mutation Mutation ID Sample Name Cancer Type
chr13:g.77897539G>T COSN8421176 AOCS-060-1-5 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-203 aaccaaCATTTCACaaaca
0 GUGAAAUG m8a Created no TS -0.030000 -0.320000
hsa-miR-3611 aaccaacatTTCACAAaca
0 UUGUGAAG m7a (m6a->m7a) no TS -0.022000 No effect
hsa-miR-409-3p aacCAACATTtcacaaaca
0 GAAUGUUG m7b (m6c->m7b) no TS 0.004000 -0.860000
hsa-miR-4504 aaccaacaTGTCACAaaca
1
UGUGACAA m7a Disrupted -0.069000 no TS No effect
hsa-miR-4781-3p aaCCAACATTtcacaaaca
2
AAUGUUGG m8a (m7b->m8a) -0.148000 -0.175000 -0.010000
hsa-miR-489 aaccaacATGTCACaaaca
0 GUGACAUC m7a Disrupted NA NA 0.280000
hsa-miR-542-3p aaccaacaTGTCACAaaca
1
UGUGACAG m7a Disrupted -0.061000 no TS 0.010000
hsa-miR-758 aaccaacatGTCACAAAca
7
UUUGUGAC m8a (m8a->m7a) -0.213000 -0.053000 0.320000

Mutation Mutation ID Sample Name Cancer Type
chr13:g.77897989A>G COSN1626463 RK001_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1245b-5p aattaagAAGGCCTcgtcg
0 UAGGCCUU m7b Created no TS -0.199000 -0.120000
hsa-miR-1248 aattAAGAAGGcctcgtcg
0 ACCUUCUU m7b Created no TS -0.148000 -11.550000
hsa-miR-3142 aattaagAAGGCCTcgtcg
0 AAGGCCUU m7b Created no TS -0.189000 -0.370000
hsa-miR-3160-5p aattaAGAAAGCCtcgtcg
14
GGCUUUCU m8a Disrupted -0.230000 -0.072000 1.770000
hsa-miR-3188 aattaagaAAGCCTCgtcg
9
AGAGGCUU m7b Disrupted -0.201000 no TS 2.140000
hsa-miR-1245b-5p aattaagAAGGCCTcgtcg
0 UAGGCCUU m7b Created no TS -0.199 -0.12
hsa-miR-1248 aattAAGAAGGcctcgtcg
0 ACCUUCUU m7b Created no TS -0.148 -11.55
hsa-miR-3142 aattaagAAGGCCTcgtcg
0 AAGGCCUU m7b Created no TS -0.189 -0.37
hsa-miR-3160-5p aattaAGAAAGCCtcgtcg
0 GGCUUUCU m8a Disrupted -0.23 -0.072 1.77
hsa-miR-3188 aattaagaAAGCCTCgtcg
0 AGAGGCUU m7b Disrupted -0.201 no TS 2.14

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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