SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_000110
Gene Symbol: DPYD
Description: Homo sapiens dihydropyrimidine dehydrogenase (DPYD), transcript variant 1, mRNA.
Gene Location: chr1(-):97543299-98386615
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr1:g.97078115A>C COSN10057062 C0054T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr1:g.97078138A>G COSN5380068 RK076_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-26b-3p gtttGAACAGagctcaaag
 0 CCUGUUCU m6b Created no TS -0.089000 -0.290000
hsa-miR-27b-5p gtttgaacaAAGCTCaaag
 0 AGAGCUUA m6b Disrupted -0.131000 no TS 0.160000
hsa-miR-3670 gtttgaacaGAGCTCaaag
 0 AGAGCUCA m6b Created no TS -0.147000 -0.010000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.97078560C>G COSN14523745 8034061 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1261 aaaatgTATCCAaggaaac
 2
 AUGGAUAA m6b Disrupted -0.115000 no TS 0.120000
hsa-miR-1915-5p aaaatgtatGCAAGGaaac
 0 ACCUUGCC m6b Created no TS -0.168000 -1.600000
hsa-miR-212-5p aaaatgtatCCAAGGaaac
 12
 ACCUUGGC m6b Disrupted -0.159000 no TS 4.890000
hsa-miR-3189-3p aaaatgtatCCAAGGaaac
 12
 CCCUUGGG m6b Disrupted -0.161000 no TS 4.680000
hsa-miR-502-5p aaaatgtatGCAAGGAaac
 13
 AUCCUUGC m7b (m6b->m7b) -0.126000 -0.387000 -3.290000
hsa-miR-5689 aaaaTGTATGCaaggaaac
 2
 AGCAUACA m7b Created -0.142000 -0.509000 -0.680000
hsa-miR-1261 aaaatgTATCCAaggaaac
 2
 AUGGAUAA m6b Disrupted -0.115000 no TS 0.120000
hsa-miR-1915-5p aaaatgtatGCAAGGaaac
 0 ACCUUGCC m6b Created no TS -0.168000 -1.600000
hsa-miR-212-5p aaaatgtatCCAAGGaaac
 12
 ACCUUGGC m6b Disrupted -0.159000 no TS 4.890000
hsa-miR-3189-3p aaaatgtatCCAAGGaaac
 12
 CCCUUGGG m6b Disrupted -0.161000 no TS 4.680000
hsa-miR-502-5p aaaatgtatGCAAGGAaac
 13
 AUCCUUGC m7b (m6b->m7b) -0.126000 -0.387000 -3.290000
hsa-miR-5689 aaaaTGTATGCaaggaaac
 2
 AGCAUACA m7b Created -0.142000 -0.509000 -0.680000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.97078847A>G COSN5745752 HCC162 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-551b-5p aaaatatgTGATTTCaaaa
 13
 GAAAUCAA m7a Created -0.075000 -0.075000 No effect
hsa-miR-5580-3p aaaATATGTGatttcaaaa
 0 CACAUAUG m7a (m6b->m7a) -0.092000 no TS 0.060000
hsa-miR-551b-5p aaaatatgTGATTTCaaaa
 13
 GAAAUCAA m7a Created -0.075000 -0.075000 No effect
hsa-miR-5580-3p aaaATATGTGatttcaaaa
 0 CACAUAUG m7a (m6b->m7a) -0.092000 no TS 0.060000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.97078896A>G COSN4892539 PCSI_0083_Pa_X [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3160-3p cttgtgtTCAGCTCTttcc
 5
 AGAGCUGA m8a Disrupted -0.276000 no TS 0.270000
hsa-miR-4537 cttgtgtTCGGCTCtttcc
 0 UGAGCCGA m7b Created no TS -0.369000 -15.530000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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