| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_012074 |
|---|---|
| Gene Symbol: | DPF3 |
| Description: | Homo sapiens D4, zinc and double PHD fingers, family 3 (DPF3), mRNA. |
| Gene Location: | chr14(-):73136659-73360809 |
| Browse Associations | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr14:g.72669983A>T | COSN14942424 | LP6005409-DNA_G03 | [oesophagus][NS][carcinoma][adenocarcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3122 |
acaGTCCCAAgaatgaccg |
10 |
GUUGGGAC | m7b | (m7b->m6c) | -0.179000 | no TS |
15.190000 |
|
| hsa-miR-3913-5p |
acaGTCCCAAgaatgaccg |
10 |
UUUGGGAC | m7b | (m7b->m6c) | -0.189000 | no TS |
1.060000 |
|
| hsa-miR-635 |
acagtCCCAAGaatgaccg |
10 |
ACUUGGGC | m6b | Disrupted | -0.129000 | no TS |
7.080000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr14:g.72670018G>A | COSN7025994 | 8013222 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-136-5p |
ccctggggcAATGGAGaag |
11 |
ACUCCAUU | m7b | (m6b->m7b) | -0.045000 | -0.147000 |
0.060000 |
|
| hsa-miR-181a-3p |
ccctggggCGATGGagaag |
5 |
ACCAUCGA | m6b | Disrupted | -0.173000 | no TS |
1.150000 |
|
| hsa-miR-3189-5p |
cccTGGGGCAatggagaag |
0 | UGCCCCAU | m7a | (m6b->m7a) | no TS | -0.197000 |
-0.430000 |
|
| hsa-miR-4317 |
ccctggGGCAATGgagaag |
0 | ACAUUGCC | m7b | Created | no TS | -0.114000 |
-0.310000 |
|
| hsa-miR-4758-3p |
cccTGGGGCAatggagaag |
0 | UGCCCCAC | m7a | (m6b->m7a) | no TS | -0.191000 |
-0.050000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr14:g.72670126C>A | COSN7025995 | 8034061 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1183 |
caaggCTACAGTatttctt |
0 | CACUGUAG | m7b | Created | no TS | -0.315000 | No effect | |
| hsa-miR-200b-3p |
caaggctaCAGTATTtctt |
0 | UAAUACUG | m7b | Created | no TS | -0.134000 |
-6.480000 |
|
| hsa-miR-200c-3p |
caaggctaCAGTATTtctt |
0 | UAAUACUG | m7b | Created | no TS | -0.134000 |
-8.060000 |
|
| hsa-miR-20b-3p |
caaggCTACAGTatttctt |
0 | ACUGUAGU | m7a | Created | NA | NA |
-10.620000 |
|
| hsa-miR-3137 |
caagGCTACAGtatttctt |
0 | UCUGUAGC | m7b | Created | no TS | -0.255000 |
-4.510000 |
|
| hsa-miR-429 |
caaggctaCAGTATTtctt |
0 | UAAUACUG | m7b | Created | no TS | -0.107000 |
-4.000000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr14:g.72670517G>C | COSN8588918 | J74_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-3648 |
cggctccCCGCGGCagacc |
0 | AGCCGCGG | m7b | Disrupted | -0.501000 | no TS |
3.780000 |
| hsa-miR-4706 |
cggcTCCCCGCggcagacc |
1 |
AGCGGGGA | m7b | Disrupted | -0.110000 | no TS |
1.020000 |
| hsa-miR-4723-5p |
cggCTCCCCCcggcagacc |
1 |
UGGGGGAG | m7b | (m6c->m7b) | -0.191000 | -0.240000 | No effect |
| hsa-miR-4749-5p |
cggcTCCCCGCggcagacc |
1 |
UGCGGGGA | m7b | Disrupted | -0.128000 | no TS |
0.020000 |
| hsa-miR-5698 |
cggCTCCCCCcggcagacc |
1 |
UGGGGGAG | m7b | (m6c->m7b) | -0.172000 | -0.239000 | No effect |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 72670980 | rs144929103 | C | C |
hsa-miR-149-3p hsa-miR-4723-5p hsa-miR-4728-5p hsa-miR-5698 hsa-miR-6757-5p hsa-miR-6785-5p hsa-miR-6797-5p hsa-miR-6825-5p hsa-miR-6870-5p hsa-miR-6883-5p hsa-miR-7111-5p |
1 1 1 1 2 1 2 1 1 1 1 |
ccatCCCTCCCcc ccatccCTCCCCC ccatCCCTCCCcc ccatccCTCCCCC cCATCCCTccccc ccatCCCTCCCcc ccaTCCCTCCccc ccatcCCTCCCCc ccatccCTCCCCC ccatCCCTCCCcc ccatccCTCCCCC |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N N N N |
-0.194 -0.191 -0.194 -0.172 -0.093 -0.194 -0.131 -0.195 -0.182 -0.175 -0.191 |
| T |
hsa-miR-2392 hsa-miR-4271 hsa-miR-4533 hsa-miR-4725-3p hsa-miR-4747-5p hsa-miR-5196-5p hsa-miR-625-5p hsa-miR-6780b-5p |
2 1 2 1 1 1 1 1 |
CCATCCTtccccc ccatcCTTCCCCc ccaTCCTTCCccc ccatcCTTCCCCc ccatCCTTCCCcc ccatCCTTCCCcc ccatccTTCCCCC ccatcCTTCCCCc |
Created Created Created Created Created Created Created Created |
N N N N N N N N |
-0.132 -0.127 -0.102 -0.117 -0.143 -0.19 -0.119 -0.136 |